Fragile X syndrome (FXS) is a well-recognized cause of mental retardation and developmental delay in males. Alongside the well-documented clinical characteristics of the condition, recent advances in technology and methodology have begun to define FXS at a number of different levels: genetic, brain structure and function, cognition, and behavior. This article suggests that the FXS phenotype is not merely a juxtaposition of spared and impaired functions but rather may be characterized by an inhibitory control deficit that interferes with the individual's ability to modulate output causing perseverative responding across various skill areas. It is further suggested that an inability to modulate arousal may be at least one cause for the inhibitory control deficit that typifies the FXS phenotype. The approach to understanding atypical development outlined here holds exciting promise for future research in FXS and other developmental disorders. 相似文献
Cognitive behaviour therapy is effective for obsessive-compulsive disorder and for obsessive-compulsive spectrum disorders such as trichotillomania. Unfortunately, many people with these disorders, especially those living in rural areas, have limited access to treatment. Telephone-administered cognitive behaviour therapy may help address this problem. In a recent study of telephone treatment for obsessive-compulsive disorder, we found that such treatment was often effective (42% in remission at post-treatment, and 47% in remission at 12-week follow-up). This article presents 2 case reports of the same treatment, applied to obsessive-compulsive spectrum disorders (trichotillomania and compulsive skin picking). Treatment was associated with symptom reduction for both participants, although one subsequently relapsed. Possible reasons for relapse are discussed. The findings encourage further studies to identify the characteristics of people most likely to benefit from telephone treatment for spectrum disorders. 相似文献
In this article I review the history and publication trends of the behavioral assessment (BA) section of the journal, outline future directions for the BA section and suggest avenues for future assessment research. BA began as a stand-alone journal in 1978 and was incorporated as a regular section of Behaviour Research and Therapy (BRT) in 1992. Throughout this article I will use 'BA' to refer to both the stand-alone assessment journal and the assessment section of BRT. Since its inception, the scope of BA has been broad, with behavioral assessment defined to include the assessment of motoric, cognitive, emotional and physiological responses. Several publication trends are identified, including a declining frequency in the number of submitted and published articles on behavioural assessment. This parallels the declining number of assessment articles published elsewhere. Despite these trends, assessment research continues to form a vital foundation for other types of psychological research (e.g. treatment outcome studies), and there is a continued need for assessment-related research. A number of potentially fruitful directions for assessment research are suggested. 相似文献
One hundred sixty-six pregnant or parenting adolescent females completed a survey regarding early sexual experiences (wanted and unwanted), family dysfunction and violence, and health-risky behaviors occurring prior to age 18. Fifty-three percent had at least one unwanted sexual experience. Younger age at first unwanted sexual experience was associated with younger age at first wanted sexual experience. Adolescent females with an unwanted sexual experience, as compared to those without, were more likely to be victims of physical violence, to have run away, to be substance abusers, and to have family members with drug or alcohol problems. Four factors explained 39% of the variance in age at first pregnancy: presence of a family member with a drinking problem, age first got hit with a belt or other object by a family member, age first got drunk, and age at first wanted sexual experience. It was concluded that the prevention of teenage pregnancy entails a multifaceted approach that addresses family life, early sexual experiences, and health-risky behaviors. 相似文献
Introduced the Pediatric Emotional Distress Scale (PEDS), which was developed to quickly assess behaviors identified in empirical and theoretical literature as significantly elevated in children after experiencing traumatic events. The 21-item parent-report rating scale includes 17 general behavior items and 4 trauma-specific items. Factor analyses on the 17 items, with 475 two- to ten-year-olds (traumatic event exposure and nontraumatic event exposure), yielded 3 reliable factors labeled Anxious/Withdrawn, Fearful, and Acting Out. Factor and total scores were shown to have good internal consistency, and both test-retest and interrater reliability were at acceptable levels. Discriminant analyses demonstrated the PEDS could distinguish traumatic event exposure and nonexposure groups, although maternal education should be a significant consideration in interpretation. Future research with diverse populations who have documented trauma is needed to enhance the utility of the full PEDS scale. 相似文献
Classical Probability in the Enlightenment. LORRAINE DASTON, 1988. Princeton, Princeton University Press. xviii + 423 pp., US$19.95 (paperback). ISBN 0–691–08497–1, 0–691–00644‐X (paperback)
Following Form and Function: a Philosophical Archaeology of Life Science. STEPHEN T. ASMA, 1996. Evanston, IL, Northwestern University Press. xiii + 232 pp., price not available
Concepts and Methods in Evolutionary Biology. ROBERT N. BRANDON, 1996. Cambridge, Cambridge University Press. xiv+221 pp., $US59.95 (hardback), $Can 27.50 (paperback). ISBN 0–521–49545–9 (hardback), 0–521–49888–0 (paperback)
The Completeness of Scientific Theories: on the Derivation of Empirical Indicators within a Theoretical Framework: the Case of Physical Geometry. The University of Western Ontario Series in Philosophy of Science, Volume 53. MARTIN CARRIER, 1994. Dordrecht, Kluwer. xviii + 248 pp., price not available. ISBN 0–7923–24757 (hardback)
The Philosophy and History of Molecular Biology: New Perspectives. Boston Studies in the Philosophy of Science, Volume 183. SAHOTRA SARKAR (Ed.), 1996. Dordrecht, Kluwer. 264 pp., $US127. ISBN 0–7923–3947–9
Awareness: What it is, What it does. CHRIS NUNN, 1996. London and New York, Routledge. price not available. ISBN 0–415–13227–4 相似文献