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21.
Fragile X syndrome (FXS) is a well-recognized cause of mental retardation and developmental delay in males. Alongside the well-documented clinical characteristics of the condition, recent advances in technology and methodology have begun to define FXS at a number of different levels: genetic, brain structure and function, cognition, and behavior. This article suggests that the FXS phenotype is not merely a juxtaposition of spared and impaired functions but rather may be characterized by an inhibitory control deficit that interferes with the individual's ability to modulate output causing perseverative responding across various skill areas. It is further suggested that an inability to modulate arousal may be at least one cause for the inhibitory control deficit that typifies the FXS phenotype. The approach to understanding atypical development outlined here holds exciting promise for future research in FXS and other developmental disorders.  相似文献   
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How do observers search through familiar scenes? A novel panoramic search method is used to study the interaction of memory and vision in natural search behavior. In panoramic search, observers see part of an unchanging scene larger than their current field of view. A target object can be visible, present in the display but hidden from view, or absent. Visual search efficiency does not change after hundreds of trials through an unchanging scene (Experiment 1). Memory search, in contrast, begins inefficiently but becomes efficient with practice. Given a choice between vision and memory, observers choose vision (Experiments 2 and 3). However, if forced to use their memory on some trials, they learn to use memory on all trials, even when reliable visual information remains available (Experiment 4). The results suggest that observers make a pragmatic choice between vision and memory, with a strong bias toward visual search even for memorized stimuli.  相似文献   
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Arata CM  Stafford J  Tims MS 《Adolescence》2003,38(151):567-579
The present study surveyed 930 high school students regarding self-reported alcohol use, their perceptions of parents and peers, and the negative consequences of drinking. Two-fifths of males and one-fifth of females reported frequent problem (binge) drinking. Problem drinkers reported more negative consequences associated with drinking. In addition, problem drinkers reported greater susceptibility to peer pressure, perceived their peers as drinking more, and reported less parental monitoring and more use of alcohol by parents. The results demonstrate the importance of both parent and peer variables in adolescent substance use and highlight the negative consequences of drinking reported by high school students.  相似文献   
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The present study explored the possibility that notetaking would help accuracy-minded interviewers to avoid cognitive expectation biases. Interviewers in simulated employment interviews were given bogus pre-interview expectations about their applicants and were either encouraged or not encouraged to take extensive notes. Consistent with past research on accuracy-motivated interviewers, both notetaking and non-notetaking interviewers avoided creating self-fulfilling prophecies. Of central interest, notetaking reduced the cognitive biasing effect of negative expectations on interviewers' overall impressions of their applicants, but failed to reduce cognitive bias in interviewers' evaluations of expectation-specific applicant characteristics. In conjunction with the motivation to form accurate impressions, notetaking can help to reduce the impact of erroneous pre-interview expectations in interviewer final evaluations.  相似文献   
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Argument about euthanasia in Australia intensified following the world's first legal euthanasia death of Bob Dent under the Northern Territory's short-lived Rights of the Terminally Ill Act 1995. This paper takes stock of the implacably opposed positions on euthanasia following Bob Dent's death, which provides a focus for the controversy, and identifies the key doctrines which separate adversaries in the euthanasia debate and their associated incommensurable intuitions.  相似文献   
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The purpose of the current study was to develop and evaluate a measure of maternal reward responsivity in parenting. Deficits in reward responsivity, a common feature of depression, may contribute to maladaptive parenting behaviors. Reward responsivity is an individual difference in reactivity to pleasurable stimuli and represents a key motivational component that could contribute to the frequency and quality of mothers’ interactions with their infants. However, there is currently no measure of reward responsivity in parenting, which would be necessary to evaluate the link between mother reward responsivity, behaviors towards their infant, and infant behavior. Therefore, the current study reports on the development and initial evaluation of a self-report measure of reward responsivity in parenting, the Mother Inventory of Reward Experience (MIRE). We evaluated the MIRE among 200 mothers (M?=?28.45, SD?=?5.50) recruited from a pediatric primary care center. After item analysis, 22 items were retained and displayed high internal consistency reliability and test re-test reliability. Convergent validity was established via a significant correlation with global reward responsivity. Concurrent validity was established via significant correlations with depressive symptoms, parenting stress, and child behavior problems. Incremental validity of the MIRE over a measure of global reward responsivity was supported. These results support the reliability and validity of the MIRE as a measure of reward responsivity in parenting.  相似文献   
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Research evidence has been accumulating for the efficacy of dialectical behaviour therapy (DBT) for binge eating. However, support for its effectiveness and transportability beyond efficacy trials is lacking. The current study evaluated the feasibility of group-based DBT for binge eating within the context of an operating community clinic. Women ages 24-49 (M?=?39.60, SD?=?9.53) with either subthreshold and full-threshold binge eating disorder or bulimia nervosa formed the group and comprised the sample (n?=?5 treatment completers). Positive outcomes included significant improvement in both binge eating and secondary outcomes with the Eating Disorder Inventory subscales of Bulimia, Ineffectiveness, Perfectionism and Interpersonal Distrust. Attrition was elevated compared with previous efficacy trials, suggesting the need for increased attention to how to improve retention within routine practice settings. Given our limited sample size, these findings are viewed as promising but preliminary.  相似文献   
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