Magnitude and duration of the effects of cocaine on conditioned and adjunctive behaviors in the chimpanzee.

Characteristic patterns of conditioned key-pressing were maintained in the chimpanzee under a multiple 30-response fixed-ratio, 10-minute fixed-interval schedule of food presentation. Adjunctive drinking occurred with regularity during the fixed-interval schedule and, with less frequency, during 1-minute timeout periods that followed each food presentation; drinking seldom occurred during the fixed-ratio schedule. Cocaine increased key pressing under the fixed-interval schedule at doses between .1 and 3.0 mg/kg, but adjunctive drinking and key pressing under the fixed-ratio schedule did not increase at any dose. Conditioned and adjunctive behaviors were disrupted and suppressed for different durations at 10,0 mg/kg, a dose which induced convulsive seizures within 10 minutes after intramuscular injection. A time-course analysis showed the magnitude and duration of the effects of cocaine on key pressing under the fixed-interval schedule and on adjunctive drinking to be dose-related. Moreover, a given dose of cocaine had diverse effects, depending on the behavior and the time since drug administration.     

Effects of d-amphetamine on self-aggression and posturing in stumptail macaques

The behavioral effects of d-amphetamine sulfate were studied in adult male stumptail macaques living within a large heterogeneous group in an outdoor enclosure. Among five subjects that received a range of doses (.01 to .3 mg/kg), d-amphetamine increased self-aggressive behavior and abnormal posturing in subjects that exhibited these types of behavior prior to drug administration, but it had no effect in subjects not exhibiting those activities in the absence of the drug. For the former subjects, the dose-effect curves for self-aggression were of an inverted U-shape analogous to the effect of d-amphetamine on schedule-controlled behavior. Over the range of doses studied, the curve for abnormal posturing was monotonic. The data indicate that d-amphetamine can have effects on untrained behavior in individual animals in a quasinatural environment that are qualitatively and quantitatively similar to the behavioral effects observed in other laboratory environments, and that d-amphetamine does not evoke or increase a behavioral response in individual subjects that do not exhibit the response in the absence of the drug.     

Adult age differences in letter-level and word-level processing

Older and young adults' letter detection and lexical decision performance were examined as word frequency varied to determine whether there were age differences in word recognition. Allen and Madden (1989) found that older adults' pattern of reaction time (RT) across word frequency categories was different from young adults' pattern for a letter detection task. In this study, for both letter detection and lexical decision tasks, older adults exhibited a monotonically decreasing RT function as word frequency increased. However, young adults exhibited a nonmonotonic RT function across word frequency for the letter detection task but a monotonically decreasing RT function as word frequency increased for the lexical decision task. An expanded parallel input serial analysis model of word processing was hypothesized.     

VideoNoter: A productivity tool for video data analysis

The software described in this paper, VideoNoter, addresses the need for tools that support annotation and retrieval of video data and organize the presentation of multiple analyses of the same data. Video is widely perceived as an important medium for psychological research, because video recording makes the fleeting particulars of human interaction available as data for detailed analysis, while retaining much of the context of the event. Though the benefits of using video data are high, the process can be prohibitively time-consuming. We have developed a prototype computer-based video analysis tool that can enhance the productivity of the video analysis process. In this paper, we report on the design and implementation of VideoNoter, and we discuss how it facilitates video data analysis.     

RITALIN VS. RESPONSE COST IN THE CONTROL OF HYPERACTIVE CHILDREN: A WITHIN-SUBJECT COMPARISON

A within-subject comparison was made of the effects of methylphenidate (Ritalin) and response cost in reducing the off-task behavior of two boys, 7 and 8 years of age, who had been diagnosed as having an attentional deficit disorder with hyperactivity. Several dosages of Ritalin (5 to 20 mg/day) were evaluated with the results indicating varying effects of the drug for both children. Response cost (with free-time as the reinforcer) was superior to Ritalin in raising levels of on-task behavior and in improving academic performance.     

Strategies in cross-modality matching

Subjects were tested on cross-and within-modality matching conditions with either a 5-sec or a 20-sec delay imposed between standard and comparison stimuli. Half the subjects were informed before the trial of what the comparison modality would be, while the others were not. There was a strong effect of instructions on the cross-modality conditions, but little on the within-modality conditions. The informed subjects showed better performance in the haptic-visual condition, while for the uninformed subjects, visual-haptic performance was better. The results suggest the importance of subjects’ processing strategies in cross-modality performance.     

Counting eliminates the repetition effect in judgments of temporal duration.

College student subjects estimated the duration of time intervals (8–54 sec) by counting or not (N=35 per group). Counting eliminated the repetition effect (a decline in the magnitude of estimations across trials), and resulted in a truncation of the psychophysical function. The former result was interpreted as contrary to Treisman's (1963) model. The latter result was attributed to the effortfulness of counting, which was established in a subsequent experiment.     

Operant conditioning of epileptic neurons in monkeys and its theoretical application to EEG operant conditioning in humans

This paper reviews a series of previous reports which summarize the physiology of chronic experimental epileptic foci in monkeys. It is shown that such monkeys can be trained to bidirectionally control the firing rates of normal and epileptic neurons which comprise the epileptic focus. As a result of this acquired operant performance, the monkeys show both a decrease in clinical seizures as well as a decrease in single unit epileptic activity. The EEC correlate of this change in single unit epileptic actvity is generalized EEG desynchronization. The conclusion from these data would indicate epileptic neurons can be operantly controlled and this control is not correlated with any specific EEG pattern. This brings to question the specificity of the SMR in EEG biofeedback paradigms which treat human epilepsy. This author feels that the result from such biofeedback studies are the result of the patient learning to manipulate electrical events within the CNS pathways through which the seizure propagates and is not contingent upon specific EEG frequencies.