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351.
Mothers (N = 168, M age = 37.0 yr., SD = 4.6) responded to a questionnaire of scales measuring sources of stress and symptoms of stress within themselves, and symptoms of stress in their 5-8-yr.-old children (61 girls, 98 boys; M age = 7.3 yr., SD = 1.0). Scores on all scales intercorrelated significantly, indicating a relationship between maternal stress and stress of the child. Both types of stress also correlated with the frequency of punishment of the child. Both maternal stress and frequency of punishment predicted stress symptoms in the children, maternal stress being a somewhat stronger predictor.  相似文献   
352.
Like many other professions, careers guidance is currently undergoing rapid and radical change. But the Careers Service is still operating to nationally agreed 'core training objectives' which determine both initial training (Diploma in Careers Guidance Part I) and supervisory training (Diploma in Careers Guidance Part II). Recent changes influencing guidance practice and training are outlined, and the predominant mode of current supervision within the Careers Service is identified as 'managerial' in character. This is explained in terms of both the historical development of the service and its funding mechanisms. A model for supervisory practice for the future is presented, identifying three essential elements: organisational commitment, contractual agreement and an explicit framework.  相似文献   
353.
Although past-life regression therapy has not been shown to be the re-experiencing of a verifiable previous biological existence, therapists have noted similarities between the phenomenology of post-death awareness reported by regressed subjects and the phenomenology of near-death experiences (NDEs). This paper reports the results of a pilot study exploring those similarities as far as the therapeutic modality normally accommodates post-death phenomena. Similarities and differences between NDEs and post-death regression phenomena suggest new avenues of research.  相似文献   
354.
The implications of the quest for scientific credibility in relation to clinically based paediatric liaison research are considered. Some of the problems arising from particular research strategies and their relationship to clinical issues are discussed. In particular, both recognition that ambivalence about research may occur in patients and their families, clinicians and researchers, and awareness that the research process may mirror the clinical process, may be helpful in facilitating both the continuation of research and increased cohesion in the multidisciplinary team.  相似文献   
355.
Nerve injury, tissue damage, and inflammation all cause hyperalgesia. A factor contributing to this increased sensitivity is a long-term (>24 hr) hyperexcitability (LTH) in the sensory neurons that mediate the responses. Using the cluster of nociceptive sensory neurons in Aplysia californica as a model, we are examining how inflammation induces LTH. A general inflammatory response was induced by inserting a gauze pad into the animal. Within 4 days, the gauze is enmeshed in an amorphous material that contains hemocytes, which comprise a cellular immune system. Concurrently, LTH appears in both ipsilateral and contralateral sensory neurons. The LTH is manifest as increased action potential discharge to a normalized stimulus. Immunocytochemistry revealed that hemocytes have antigens recognized by antibodies to TGFβ1, IL-6, and 5HT. When a localized inflammation was elicited on a nerve, hemocytes containing the TGFβ1 antigen were present near axons within the nerve and those containing the IL-6 were on the surface. Western blots of hemocytes, or of gauze that had induced a foreign body response, contained a 28-kD polypeptide recognized by the anti-TGFβ1 antibody. Exposure of the nervous system to recombinant human TGFβ1 elicited increased firing of the nociceptive neurons and a decrease in threshold. The TGFβ1 also caused an activation of protein kinase C (PKC) in axons but did not affect a kinase that is activated in axons after injury. Our findings, in conjunction with previous results, indicate that a TGFβ1-homolog can modulate the activity of neurons that respond to noxious stimuli. This system could also contribute to interactions between the immune and nervous systems via regulation of PKC.  相似文献   
356.
Genetic testing for inherited deafness is now available within some genetics centres. This study used a structured questionnaire to assess the potential uptake of prenatal diagnosis (PND) for inherited deafness, and document the opinions of deaf and hearing individuals toward PND and termination of pregnancy (TOP) for hearing status. Participants were self-selected from the whole of the UK, of whom 644 were deaf, 143 were hard of hearing or deafened, and 527 were hearing individuals who had either a deaf parent or child. The results showed that 21% of deaf, 39% of hard of hearing and deafened, and 49% of hearing participants said they would consider PND for deafness. Six percent of deaf, 11% of hard of hearing and deafened, and 16% of hearing participants said they would consider a TOP if the fetus was found to be deaf. Two percent of deaf participants said they would prefer to have deaf children and would consider a TOP if the fetus was found to be hearing.  相似文献   
357.
Previous research has shown that interpretation biases can be experimentally induced and endure for 24 hours. In two experiments, we show that induced biases not only persist but survive changes in environmental context, including transferring to different rooms with different experimenters. In one experiment, training and testing materials were also presented in different sensory modalities without significantly reducing the magnitude of the induced bias. Furthermore, we found evidence of changes in emotional vulnerability, congruent with the direction of induced bias, which also persisted for 24 hours. Together with earlier results, these findings show that induced biases generalize over contexts and have persisting emotional consequences, suggesting that appropriately adapted training methods may contribute to developing therapeutic techniques within clinical settings.  相似文献   
358.
The current study examined the persistence and phenotypic presentation of inattention/overactivity (I/O) into early adolescence, in a sample of institution reared (IR) children adopted from Romania before the age of 43 months. Total sample comprised 144 IR and 21 non-IR Romanian adoptees, and a comparison group of 52 within-UK adoptees, assessed at ages 6 and 11 years. I/O was rated using Rutter Scales completed by parents and teachers. I/O continued to be strongly associated with institutional deprivation, with continuities between ages 6 and 11 outcomes. There were higher rates of deprivation-related I/O in boys than girls, and I/O was strongly associated with conduct problems, disinhibited attachment and executive function but not IQ more generally, independently of gender. Deprivation-related I/O shares many common features with ADHD, despite its different etiology and putative developmental mechanisms. I/O is a persistent domain of impairment following early institutional deprivation of 6 months or more, suggesting there may be a possible pathway to impairment through some form of neuro-developmental programming during critical periods of early development.  相似文献   
359.
Here we report evidence from a new eye‐tracking measure of relational memory that suggests that 9‐month‐old infants can encode memories in terms of the relations among items, a function putatively subserved by the hippocampus. Infants learned about the association between faces that were superimposed on unique scenic backgrounds. During test trials, infants were shown three faces presented on a familiar scene. All three faces were equally familiar; however, one had been presented with the test background earlier. Visual behavior was recorded continuously using a TOBII eye tracker. Infants looked preferentially at the face that matched the test background very early in the trial; however, the time course of this preferential looking effect varied as a function of delay. These results suggest that by 9 months of age infants can form memories that represent the relations among items and maintain them over short delays.  相似文献   
360.
This article reviews the position of women in the UK labour market and the increasing complexity of their employment patterns. It criticises current career theory for girls and women and examines enhancers and inhibitors of women's career development. Finally, some promising developments in theory-building for girls and women are briefly discussed, together with some implications for practice.  相似文献   
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