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291.
    
We have interpreted the literature showing left anterior hypoactivation in depression as reflecting a decrease in approach-related motivation and behaviour among depressed subjects. In support of this model, we have previously demonstrated a decreased responsiveness to reward in subclinically depressed dysphoric subjects. The current study was designed to replicate and extend those findings. Clinically depressed subjects who met DSM-IV criteria for major depression were compared to a group of nondepressed control subjects on a verbal memory task under three monetary payoff conditions: neutral, reward, and punishment. Although control subjects changed their pattern of responding in both the reward and punishment conditions, relative to the neutral condition, so as to maximise their earnings, depressed subjects did not do so during reward. The two groups did not differ during the punishment condition. These findings provide additional evidence of a decreased responsiveness to reward in depressed individuals, and are consistent with the hypothesis that the left prefrontal hypoactivation observed in depression reflects a deficit in approach-related behaviour.  相似文献   
292.
The act of observation can appear to affect the results of certain scientific experiments. Research has shown that the mind is much more than the brain. The perception of an observer may be significantly affected by the local and non-local environment, and is dependant on the time of the day, month, or year on which those measurements are made. This research has led toward a greater understanding of the structure of the universe, including its connection to consciousness and information. For example, it is demonstrated that the mind's ability to communicate information from across the solar system is much faster than the speed of light.  相似文献   
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Abstract

Neurobiological research with animals strongly suggests that the brain systems which mediate emotion overlap with those that mediate cognition to such a degree that it is difficult, if not impossible, to maintain any clear distinction between them. Possible reasons for this overlap are discussed; and a model of brain systems that simultaneously subserve emotion and cognition is presented. The model postulates the existence of three fundamental systems of this kind in the mammalian brain: a behavioural approach system, a fight/flight system, and a behavioural inhibition system. The neuropsychology of each of these systems is briefly presented.  相似文献   
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A balanced time perspective (BTP) is defined as a frequent and equal tendency to think positively about both one's past and future. A BTP is related to greater psychological well-being, such as life satisfaction and wisdom, and these BTP associations may vary cross-culturally, although few studies of BTP in non-Western countries exist. In order to advance cross-cultural comparisons of BTP, an important methodological step is to validate BTP measures in different cultures. This study aimed to develop and validate a Japanese version of the modified Balanced Time Perspective Scale (mBTPS). Japanese participants (N = 1,020, aged 18–79 years) completed the mBTPS-J, along with Japanese versions of the Zimbardo Time Perspective Inventory (ZTPI-J) and measures of well-being (life satisfaction and wisdom scales). Factor analysis of the mBTPS-J resulted in a 27-item mBTPS-J consisting of Past, Present, and Future subscales. Correlations between the relevant mBTPS-J and ZTPI-J subscales, and with the well-being measures, supported both convergent and predictive validity, respectively. The demonstrated psychometric strengths of the mBTPS-J will allow for specific testing of important cross-cultural questions.  相似文献   
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Evidence for proximal risk factors for suicide is based on case–control psychological autopsy studies, with these reports showing that mood and substance use disorders are the most prevalent mental disorders among suicide decedents worldwide and are associated with marked risk. However, moderators of risk and the degree of risk associated with (nonalcohol) drug use disorder are unknown. A comprehensive search was used to identify 35 case–control psychological autopsy studies published worldwide over a 30‐year period that were metaanalyzed using random effects models. Major depression, odds ratio (95% confidence interval) = 9.14 (5.53, 15.09), and drug use disorder, OR (95% CI) = 7.18 (3.22, 16.01), had large effect sizes, among other results. Risk estimates associated with major depression were greater in studies with a larger proportion of women and those conducted in Asia compared with other regions. There was no evidence of publication bias or that any one study had a disproportionate impact on findings. Risk for suicide associated with major depression appears to be moderated by sex and/or world region. Drug use disorder is a potent risk factor, illustrating the importance of assessing drug use in clinical risk assessment.  相似文献   
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This article aims to explore the attitudes and behaviors of persons with intellectual and developmental disabilities (IDD) related to their information privacy when using information technology (IT). Six persons with IDD were recruited to participate to a series of 3 semistructured focus groups. Data were analyzed following a hybrid thematic analysis approach. Only 2 participants reported using IT every day. However, they all perceived IT use benefits, such as an increased autonomy. Participants demonstrated awareness of privacy concerns, but not in situations involving the use of technology; their awareness is not transferred to the abstract context of IT use. Privacy breaches were revealed to be a major risk for persons with IDD, who did not seem to understand how their personal information was used. Most protection mechanisms and tools reported were those suggested and implemented by caregivers and close relatives who had a great influence on the participants’ attitudes and behaviors toward IT and privacy. Our findings suggest that when using IT, persons with IDD often experience the consequences of a trade-off between autonomy and privacy. Further research and action is needed to support persons with IDD to understand and balance the benefits of IT use and the inherent threats to information privacy.  相似文献   
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