Presurgical Language Mapping

ABSTRACT— Neurosurgical procedures for tumors or intractable epilepsy are often accompanied by risk to postoperative cognitive function; surgery in the left temporal or frontal lobes, for example, can place language functions at risk. Hence, prior to tissue extraction, one common surgical goal is to attempt to identify frontal and temporal regions that should be spared in order to preserve language function. We describe how basic research on false memory for word lists has led to a novel approach for identifying such language-related regions in healthy controls. That is, rapid presentation of semantically related words (e.g., bed , rest , awake ) and phonologically related words (e.g., peep , weep , heap ) with instructions to attend to relations among the words elicits activity in underlying language networks. Furthermore, it is often possible to identify the neural underpinnings of these networks in an individual person in about an hour of functional magnetic resonance imaging (fMRI) scanning. We conclude by suggesting directions for future research with this lexical-processing protocol, the overarching goal being to link basic cognitive science and clinical practice.     

Charting the Road of Inquiry: Deleuze's Humean Pragmatics and the Challenge of Badiou

This essay responds to Badiou's charge that Deleuze fails to set forth a philosophy that is “beyond Gategorical oppositions.” It is argued that this criticism of Deleuze is founded upon a misreading of the Deleuzean distinction between the virtual and the actual, a reading that carries forward Badiou's misreading of Spinoza and, hence, of Deleuze's Spinozism. With this corrected, we show how the virtual‐actual distinction operates within the experimental philosophy, or pragmatics, that Deleuze, and later Deleuze and Guattari, sets forth. It is this pragmatics that is precisely the philosophy of difference that is beyond categorical oppositions. Through a comparison of Deleuzean pragmatics with the work of Hume and Peirce, we are able to respond to Badiou's further criticism that Deleuze's philosophy fails to understand the conditions for creativity in thought and culture. This criticism is itself resolved once one corrects for Badiou's misreading of Deleuze's virtual‐actual distinction.     

An association between the DAT1 polymorphism and smoking behavior in young adults from the National Longitudinal Study of Adolescent Health.

Associations between smoking behavior and polymorphisms in the dopaminergic genes (DAT1 and DRD2) were tested by using within- and between-family measures of allelic transmission in 2,448 young adults from the National Longitudinal Study of Adolescent Health. The 9-repeat allele of the dopamine transporter gene polymorphism (DAT1) was inversely associated with smoking in samples that included all subjects and only those who had initiated smoking, accounting for approximately 1% of the variance. Never smokers and current nonsmokers had an excess transmission of the 9-repeat allele compared with regular smokers, suggesting a protective effect of the 9-repeat allele, which is hypothesized to alter synaptic dopamine levels.     

Cognitive Behavioral Treatment of Panic Disorder and Agoraphobia in a Multiethnic Urban Outpatient Clinic: Initial Presentation and Treatment Outcome

Few studies examine the effectiveness of panic control treatment across diverse ethnic groups. In this paper we present data on 40 patients (African American, n = 24; Caucasian, n = 16) with panic disorder and comorbid agoraphobia who presented at an anxiety disorder clinic in an inner-city area. On initial assessment both groups were similar on psychometric measures, and both groups moderately improved with treatment though significant residual symptoms remained. We illustrate, through case examples, a variety of clinical issues that need to be addressed when providing treatment to multiethnic African American clients with panic disorder and agoraphobia.     

The Role of Maternal Employment, Role-Altering Strategies, and Gender in College Students’ Expectations of Work–Family Conflict

We examined the relationship between maternal employment and college students’ expected work–family conflict as well as the relationship between expected conflict and the anticipated use of family-altering and career-altering strategies. Results indicated a positive relationship between the extensiveness of maternal employment and expected work–family conflict only for men. In addition, students who expected extensive work–family conflict anticipated delaying marriage, limiting the number of children they will have, and, in the case of men, intending not to have children. There was no relationship between expected work–family conflict and the anticipated use of career-altering strategies. Implications of the findings and directions for future research are discussed.     

Why inflammation and the activities of the immune system matter for social and personality psychology (and not only for those who study health)

A growing body of research finds that the activities of the immune system—in addition to protecting the body from infection and injury—also influence how we think, feel, and behave. Although research on the relationship between the immune system and psychological and behavioral outcomes has most commonly focused on the experiences of those who are ill or experiencing an acute immune response, we propose that the immune system may also play a key role in influencing such outcomes in those who are healthy. Here, we review theory and research suggesting that inflammation—a key component of the immune response to pathogens and stressors—may play an important modulatory role in shaping emotions, motivation, cognition, and behavior, even among those without symptoms of illness. Moreover, because inflammation occurs in response to a number of everyday social experiences (e.g., loneliness and stress), we propose that it may be an important mediator of many psychological and behavioral outcomes that are of interest to social and personality psychologists. We close by discussing potential opportunities for researchers looking to incorporate psychoneuroimmunology (PNI) into their area of inquiry.     

Video Games can Increase Creativity,but with Caveats

Although many studies have focused on aggression or visual-spatial cognition effects of video games, the problem-solving aspects have been largely ignored. This study sought to expand the existing literature on video game effects by focusing on a rarely-tested outcome: creative production. As a game with few rules and a high amount of player freedom, Minecraft exemplifies a game that fosters players’ abilities for creative expression. This experimental study included 352 undergraduates and it compared the effect of playing Minecraft on creativity measures compared to watching a TV show (passive control), a driving game (game control), and playing Minecraft with specific instructions (an instructional control). A within-subjects analysis found a significant correlation between trait creativity and game play habits. Between-groups experimental analyses showed that players randomly assigned to play Minecraft without instruction demonstrated significantly higher scores on post-game creativity measures compared to those who played Minecraft with instructions to “be creative,” those who played a driving game, or those who watched a television show. Results indicate that effects are not solely predicted by game mechanics, but also by the way the player plays.     

Stress and inflammation among older adults: The moderating role of religiosity

Chronic stress weakens the immune system and leads to heightened bodily inflammation, which in turn is linked with serious health conditions. This study examined whether religiosity moderates the relationship between stress and inflammation (measured by C-reactive Protein (CRP)). A sample of 4,734 community-dwelling older adults was drawn from the 2006 wave of the Health and Retirement Study. Logistic regression was used to analyze the relationship between chronic stress (8-item index), inflammation (high CRP level), and religiosity (organizational, nonorganizational, and intrinsic), controlling for other factors. Higher levels of stress were significantly associated with high inflammation/CRP (p = .039). Further, intrinsic religiosity acted as a moderator of this relationship (p = .024), such that the relationship between stress and inflammation is lessened for persons with higher levels of intrinsic religiosity. Higher intrinsic religiosity attenuated the effects of stress on inflammation, suggesting that individuals with stronger religious commitment/motivation may better cope with stress.