Glucose effects on memory: behavioral and pharmacological characteristics

Recent findings indicate that post-training glucose injections can modulate memory storage for inhibitory (passive) avoidance training. Experiment I extended these findings to determine whether glucose, like other memory modulating treatments, enhances memory storage when administered after training with low footshock and impairs memory storage after high footshock training. In Experiment I, male Sprague-Dawley rats were trained in a one-trial inhibitory avoidance task using either a brief footshock (0.5 mA, 0.7 s) or slightly more intense footshock kept on until escape (0.7 mA, mean escape latency = 3.4 s). Immediately after training, each rat received a subcutaneous injection of glucose (100 mg/kg). When tested for retention performance 24 h later, the glucose-injected animals exhibited enhanced retention performance for low footshock training and impaired retention for high footshock training. Experiment II determined whether pretreatment with adrenergic antagonists blocked the effects of glucose on memory. Pretreatment with the alpha- or beta-adrenergic receptor antagonists, phenoxybenzamine, or propranolol, respectively, had no effect on acquisition or retention in animals trained with the brief footshock and did not affect glucose facilitation of that memory. In animals trained to escape footshock, phenoxybenzamine did not attenuate the amnesia produced by glucose. Propranolol-pretreated animals had impaired retention whether or not they received post-training amnestic injections of glucose; glucose had no effect on retention in these amnestic animals. These findings add further support to the view that glucose release after training and treatment may represent a physiological response subsequent to epinephrine release in modulating memory storage processing.     

The effect of subject's gender on judgments of similarity and choice of a comparison other

This study examined the implications for social comparison theory of the proposition that women have lower self-confidence than men when there is a socially defined standard of performance. To this end, it was hypothesized that women would judge themselves to be similar to a lower ranked person, whereas men would judge themselves to be similar to a higher ranked person. Furthermore, it was hypothesized that women would choose to see a score lower than their own, whereas men would choose to see a score higher than their own. The results on the measure of similarity indicated that men did judge themselves to be similar to a higher ranked person, whereas women showed no consistent preferences in their judgments of similarity. The results on the choice of a comparison other were not as clear-cut.     

Postnatal development of respiratory and vocal responses during aversive classical conditioning in cats

Respiratory rate, respiration amplitude, and vocal responses were recorded in cats of different ages during classic conditioning. Vocal responses to the conditional stimulus (CS) appeared first in 8-week-old kittens, and became prominent at older ages. An increase in respiration rate occurred after the onset of the CS in cats of all ages. Similarly, the decrease of respiration amplitude was observed at all ages, but only in 8-week-old and older subjects did this response resemble an adult pattern. In 4-week-old kittens the response was characterized by an early and brief peak, suggesting an alpha conditional response (CR). Clear and significant discrimination between a warning and a safety signal was present in both respiratory and vocal responses after the age of 8 weeks.     

Achieving sex education program outcomes: points of view from students and alumni

Several inherent limitations to secondary school sex education program evaluations are: limited generalizability, lack of longitudinal research, and no clear consensus of program outcomes. With a Bureau of Health Education, Center for Disease Control study as the criterion for program outcomes, a study was undertaken to examine the immediate and long-term impact of sex education upon program participants. Two of the 20 schools in the CDC study identified as having exemplary sex education programs provided access to their students and alumni. Inventories which measured perceived achievement of 33 sex education outcomes were piloted for reliability and validity. Each inventory examined participant changes in knowledge, understanding of self, values, interaction skills, self-esteem, and fear of sex-related activities. Students were surveyed in school; alumni were surveyed through the mail. Response rates ranged from 30 to 100 percent for students and alumni at both schools. Overall there was no statistically significant difference between the perceptions of students and alumni as to achievement of investigated outcomes. Alumni responses at one school did, however, indicate some potentially weak areas of their school's program with respect to values and interaction skills outcomes. It appears that program impact may decrease with time. Thus, isolating and addressing the factors involved may be necessary. This would assist program planners and instructors to strengthen curricula and program activities in order to enhance the overall impact of sex education. The present study supports the notion that positive gains are achieved as a result of each school's sex education program, and these gains remained over time.     

Science as a justification for psychology as a social institution

Psychology seeks to justify its claims to privilege as a social institution largely on the basis of its scientific knowledge claims. These knowledge claims tend to be based on, and to reflect a particular view about the nature of science which is under increasing challenge. This situation is discussed and some of its implications examined.     

A word’s meaning affects the decision in lexical decision

The influence of an isolated word’s meaning on lexical decision reaction time (RT) was demonstrated through four experiments. Subjects in two experiments made lexical decision judgments, those in a third experiment pronounced the words used in the lexical decision task, and those in a fourth experiment quickly pronounced their first associative response to the words. Differences in lexical access time for the words were measured with the pronunciation task, and differences in meaning were assessed with the association task. Multiple regression analyses of lexical decision RT were conducted using associative RT, pronunciation RT, and other target word properties (printed frequency, length, instance dominance, and number of dictionary meanings) as predictor variables. These analyses revealed a relationship between lexical decision RT and associative RT after the effects of other variables had been partialed out. In addition, word frequency continued to have a significant relationship to lexical decision RT beyond that shared with pronunciation RT and the other variables. The results of these experiments indicate that at least some of the effect of word meaning and word frequency in lexical decision is attributable to a decision stage following lexical access.     

Postsurgical enrichment aids adult hemidecorticate rats on a spatial navigation task

The effect of environmental enrichment on normal rats, rats that received hemidecortication at birth, and rats that received hemidecortication when adult was studied in the Morris water task, which is a spatial navigation task requiring the use of distal cues for successful performance. Enrichment was achieved by housing the rats for 90 days in a large outdoor compound that was designed to model a natural environment. Adult hemidecorticated lab-raised rats were severely impaired in the acquisition of the task but neonatally hemidecorticated rats, although also impaired, showed significant sparing. Postsurgical, but not presurgical, enrichment of adult hemidecorticated rats significantly enhanced their recovery. Enrichment had little effect on neonatally decorticated rats or on normal rats. Although there were no gross anatomical changes associated with enrichment, the paradigm provides both a robust phenomena and a cortically dependent task that is ideal for investigating the processes in the remaining intact hemisphere that must support recovery.