Failure to replicate a QTL association between a DNA marker identified by EST00083 and IQ

In a paper published in this journal, a possible QTL association was reported between general cognitive ability and a marker, identified by an expressed sequence tag, EST00083 (Skuder et al., 1995). In two small samples, the frequency of the common allele of this DNA marker, which was shown to be in the threonine transfer RNA gene in mitochondrial DNA, was significantly greater in a high-IQ group than in a low-IQ group. As part of the ongoing IQ QTL Project (Plomin et al., 1995), we have attempted to replicate this QTL association. First, we found that the QTL association remained significant when we compared 51 high- and 51 -average IQ subjects, drawn in part from the samples used in the previous report. However, when we examined the association in new samples of 40 extremely high-IQ subjects and 50 average-IQ subjects, the association did not replicate. This underlies the need for replication in case-control studies of allelic association.     

Longitudinal Correlates of Arrest Status Among At-Risk Males

We examined the longitudinal adjustment, from grade 4 to grade 11, of a sample (n = 76) of boys judged to be at-risk for developing antisocial behavior patterns. We also examined subgroups of the sample differentiated by risk status and arrest records at grade 11. Antisocial behavior patterns exhibited by these boys demonstrated considerable stability over time. Differences were noted among high and lower-risk groups who were and were not arrested. In particular, measures of academic and social skills dimensions were related to better overall adjustment as indicated by lower arrest rates. Implications of these results for intervention are presented.     

Studies on pain and analgesia

The Psychological Record -     

The Impact of Resource Loss and Critical Incidents on Psychological Functioning in Fire-Emergency Workers: A Pilot Study

The relationship between critical incident exposure and resource loss, as conceptualized by Conservation of Resources (COR) theory, in predicting later psychological outcome (e.g., depressive symptoms, anger expression, and state anger) was examined in a sample of 150 fire-emergency workers from a Fire Department in a mid-sized, midwestern city. Additionally, a measure of critical incidents (Critical Incidents Inventory) was developed, and preliminary data on its validity are presented. Results from multiple regression analyses indicated that fire-emergency workers' exposure to critical incidents was directly related to their report of depressive symptoms, outward expression of anger, and state anger. Additionally, results indicated that fire-emergency workers' resource loss was strongly related to their psychological outcome. Results also suggest that resource loss may mediate the impact of critical incident stress exposure on depressive symptoms and the outward expression of anger. These results offer support to applying COR theory to populations under extreme stress.     

The effectiveness of counselling with older people: Results of a systematic review

In 2003 the British Association for Counselling and Psychotherapy (BACP) commissioned a systematic review of the research evidence relating to counselling older people. This paper reports on some of the findings of this review, particularly those which address the effectiveness of counselling with this population. Electronic searches of the research literature spanned six databases and were supplemented by hand‐searches of reference lists and key journals, along with an extensive search of the “grey” literature. The location of papers testing interventions which fall within a definition of counselling set out by the BACP, with samples aged 50 years of age or above resulted in the inclusion of 47 relevant studies. Studies investigated a variety of mental health problems in older people, particularly depression, anxiety, dementia and the psychological impact of physical conditions such as chronic obstructive pulmonary disease. Of the 47 studies, eight tested counselling as a generic treatment, 15 tested cognitive behavioural therapy, 13 tested reminiscence therapy, and 11 tested various other specific approaches. The review concluded that counselling is efficacious with older people, particularly in the treatment of anxiety and depression and outcomes are consistent with those found in younger populations. Evidence as to the efficacy of counselling interventions in the treatment of dementia is weak.