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101.
Although subchronic phencyclidine (PCP) administration is recognized as a probative method to model schizophrenia-like symptoms in animals, only a few sets of data support the hypothesis of a cognitive prefrontal cortex (PFc) dysfunction in PCP-treated monkeys and rodents. Two experiments were here conducted to further test the integrity of prefrontal function in two versions of a memory for temporal order (MTO) task administered to rats. Original versions of this task elaborated by Kesner repeatedly yielded moderate to severe performance deficits in PFc lesioned rats. MTO assessment in an eight-arm radial maze consisted in a recency discrimination between two arms previously explored in the context of sequential forced choices. In Experiment 1, 16 naive Long-Evans rats were pre-trained on a variable version of the MTO task involving randomly re-mixed sequences until they reached a group criterion. Then, rats were treated daily for 21 days with PCP (10mg/kg) or saline vehicle and were tested on the same task approximately 20 h after an injection. The performance of the groups did not differ. In Experiment 2, 16 naive Long-Evans rats untrained prior to treatment received 27 daily injections of either PCP (10mg/kg) or saline vehicle and were tested, 20 h after each injection, on a constant version of the MTO task. This time, a fixed set of four sequences of successive arm entries was repeated within each daily session as well as across days. Again, prolonged PCP exposure failed to impair discrimination of temporal order despite the stability of sequential information over time. These negative results are not consistent with long-lasting hypofrontality, a major landmark of human schizophrenia, in the PCP rat model.  相似文献   
102.
Brooks and colleagues (S. W. Allen & L. R. Brooks, 1991; G. Regehr & L. R. Brooks, 1993) have shown that the classification of transfer stimuli is influenced by their similarity to training stimuli, even when a perfect classification rule is available. It is argued that the original effect obtained by Brooks and colleagues might have resulted from two potential confounding variables. Once these confounds were controlled, the current authors did not replicate Brooks and colleagues' results in Experiment 1. Exemplar effects appeared in Experiment 2 when transfer stimuli were perceptually more similar to training stimuli than in Experiment 1. In Experiment 3, the authors obtained exemplar effects with separated stimuli, a finding that was not predicted by Brooks and colleagues' model. The authors suggest that a close perceptual match between training and transfer stimuli is necessary for the effect to occur, for both integrated and separated stimuli. The nature of this perceptual match, holistic or featural, is discussed.  相似文献   
103.
We tested the ability of the mature visual system for discrimination between types of elliptic biological motion on the basis of event kinematics. Healthy adult volunteers were presented with point-light displays depicting elliptic motion when only a single dot, a moving point-light arm, or a whole point-light human figure was visible. The displays were created in accordance with the two-thirds power kinematic law (natural motion), whereas the control displays violated this principle (unnatural motion). On each trial, participants judged whether the display represented natural or unnatural motion. The findings indicate that adults are highly sensitive to violation of the two-thirds power kinematic law. Notably, participants can easily discriminate between natural and unnatural motions without recognising the stimuli, which suggests that people implicitly use kinematic information. Most intriguing, event recognition seems to diminish the capacity to judge whether event kinematics is unnatural. We discuss possible ways for a cross-talk between perception and production of biological movement, and the brain mechanisms involved in biological motion processing.  相似文献   
104.
A dissociation between categorization and similarity was found by Rips (1989). In one experiment, Rips found that a stimulus halfway between a pizza and a quarter was categorized as a pizza but was rated as more similar to a quarter. Smith and Sloman (1994) discussed these results in terms of the role of necessary and characteristic features. In two experiments, participants had to learn to categorize novel artificial shapes composed of a nonsalient necessary feature combined with a salient characteristic feature. Participants categorized stimuli on the basis of a necessary feature, whereas their similarity judgments relied on characteristic features. The role of deep (essential) features in dissociations is considered. Results are discussed in terms of the differences between requirements of categorization and similarity judgments.  相似文献   
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The connectionist network corresponding to the nonlinear integration dynamical system associated with Kintsch's construction-integration (CI) model is analysed with linear algebra tools. This addresses some theoretical questions raised and left unanswered by Rodenhausen (1992, Psychological Review 99, 547-549). A mathematical characterization for equilibrium points, which allows an a priori enumeration of all possible asymptotic states for the integration dynamical system, given a connectivity matrix, is given. The dynamics of convergence of the integration dynamical system is characterized in some detail as well. This provides a tool for understanding CI simulations and helps in particular to let us know to what extent the outcome will depend on the initial conditions. The criteria also provide a new mathematical analysis which allows for the explicit calculation of asymptotic states of the integration process without requiring computer simulation experiments. The new mathematical analysis should facilitate comparisons of the model's predictions with behavioural data. Copyright 2001 Academic Press.  相似文献   
107.
Speeding is a preventable risky behavior that contributes to risk of accident. Readiness to change reflects an individual's recognition of and desire to change behavior. No measure to identify readiness to change has yet been validated for speeding. The Readiness to Change Questionnaire appraises readiness to change drinking behavior. The questionnaire was adapted to speeding and its psychometric properties examined. Participants (N = 112) completed the questionnaire and reported their usual driving speed. A clear component structure and acceptable internal consistency and test-retest reliability were found. Convergent validity was indicated by an association between higher readiness to change and lower driving speed. Results support the questionnaire's potential as a measure of readiness to change speeding, and advance research into the role of motivation in speeding behavior.  相似文献   
108.
Previous epidemiological studies of correlates of child and adolescent mental disorders in the general population have focused more on child/adolescent and socioeconomic/sociodemographic characteristics than on family characteristics. Moreover, there are no generally accepted methods to analyze and interpret correlates. The purpose of the Quebec Child Mental Health Survey in this regard was twofold: (1) to identify correlates of DSM-III-R internalizing and externalizing disorders according to informant (youth, parent, teacher), for three age groups (6–8, 9–11, and 12–14 years), including relevant family characteristics not considered in previous studies; and (2) to interpret the relative importance of risk indicators by ranking correlates according to strength and consistency of association across age groups. Logistic regression models suggest the inconsistency of correlates across informants. The ranking of correlates reveals that individual and family characteristics make a more important contribution than do socioeconomic characteristics, thereby supporting the relevance of proximal variables in the development of psychopathology.  相似文献   
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