Eating Disorders Inventory: Assessment of its Construct Validity in a Nonclinical French Sample of Adolescents

Recent studies have questioned the appropriateness of the original Eating Disorders Inventory (EDI) in nonclinical samples of adolescents. The main objective of the present series of studies is to systematically test the construct validity of the EDI (i.e. content, factorial, convergent, discriminant and discriminative) in a nonclinical sample of French adolescents. A total sample of 1,323 adolescents was involved in these five studies. The factorial validity and the measurement invariance of the EDI were verified through confirmatory factorial analyses. Correlation and student t-tests were also used to test the convergent and discriminative validity of the EDI. Results from the first study confirmed the unsuitability of the French original EDI for young adolescents. Items were re-worded and an adaptation for adolescents was developed (EDI-A). The following four studies provided support for the factorial validity, measurement invariance, reliability, convergent validity and discriminant validity for a short form (i.e. 24 items) of the EDI-A. The present results thus provide preliminary evidence regarding the construct validity of the 24-item EDI-A for French nonclinical adolescents. Recommendations for future uses and research activities with this instrument in French speaking adolescents are outlined.     

Automatic analysis of altered gait in arylsulphatase A-deficient mice in the open field

In current research with laboratory animals, observing their dynamic behavior or locomotion is a laborintensive task. Automatic continuous monitoring can provide quantitative data on each animal’s condition and coordination ability. The objective of the present work is to develop an automated mouse observation system integrated with a conventional open-field test for motor function evaluation. Data were acquired from 86 mice having a targeted disruption of the arylsulphatase A (ASA) gene and having lowered coordinated locomotion abilities as a symptom. The mice used were 36 heterozygotes (12 females) and 50 knockout mice (30 females) at the age of 6 months. The mice were placed one at a time into the test setup, which consisted of a Plexiglas cage (53× 34.5 × 26 cm) and two fluorescent bulbs for proper illumination. The transparent cage allowed images to be captured from underneath the cage, so image information could be obtained about the dynamic variation of the positions of the limbs of the mice for gait reconstruction. Every mouse was recorded for 10 min. Background subtraction and color filtering were used to measure and calculate image features, which are variables that contain crucial information, such as the mouse’s position, orientation, body outline, and poßible locations for the mouse’s paws. A set of heuristic rules was used to prune implausible paw features and label the remaining ones as front/hind and left/right. After we had pruned the implausible paw features, the paw features that were consistent over subsequent images were matched to footprints. Finally, from the measured footprint sequence, eight parameters were calculated in order to quantify the gait of the mouse. This automatic observation technique can be integrated with a regular open-field test, where the trajectory and motor function of a free-moving mouse are measured simultaneously.     

The right parahippocampal gyrus contributes to the formation and maintenance of bound information in working memory

Working memory is devoted to the temporary storage and on-line manipulation of information. Recently, an integrative system termed the episodic buffer has been proposed to integrate and hold information being entered or retrieved from episodic memory. Although the brain system supporting such an integrative buffer is still in debate, the medial temporal lobe appears to be a promising candidate for the maintenance of bound information. In the current work, binding was assessed by comparing two conditions in which participants had to retain three letters and three spatial locations presented either bound or separate. At the behavioral level, lower performance was found for bound information than for separate information. When contrasting the two conditions, activation in the right parahippocampal gyrus was greater for the encoding and maintenance of bound information. No activation was observed in the medial temporal lobe during the retrieval of bound information. Together, our results suggest that the parahippocampal gyrus may underlie the integrative and maintenance functions of the episodic buffer.     

Conscious recollection in autobiographical memory: an investigation in schizophrenia

Whether or not conscious recollection in autobiographical memory is affected in schizophrenia is unknown. The aim of this study was to address this issue using an experiential approach. An autobiographical memory enquiry was used in combination with the Remember/Know procedure. Twenty-two patients with schizophrenia and 22 normal subjects were asked to recall specific autobiographical memories from four lifetime periods and to indicate the subjective states of awareness associated with the recall of what happened, when and where. They gave Remember, Know or Guess responses according to whether they recalled these aspects of the event on the basis of conscious recollection, simply knowing, or guessing. Results showed that the frequency and consistency of Remember responses was significantly lower in patients than in comparison subjects. In contrast, the frequency of Know responses was not significantly different, whereas the frequency of patients' Guess responses was significantly enhanced. It is concluded that the frequency and consistency of conscious recollection in autobiographical memory is reduced in patients with schizophrenia.     

Which processes are involved in cognitive procedural learning?

Procedural memory is characterised by a relative resistance to pathology, making its assessment of the utmost importance. However, few studies have looked at the cognitive processes involved in cognitive procedural learning. In an initial experiment, we studied the role of different cognitive functions in massed cognitive procedural learning. Our results confirmed the existence of three separate learning phases and, for the first time, demonstrated the involvement of episodic memory and executive functions in the first learning phase. In a second experiment, we studied the effect of distributed learning conditions on the dynamics of procedural learning. This second study confirmed our results but showed that these conditions slow down the process of cognitive procedural learning. Our overall findings call into question the status of functionally autonomous memory system that is currently allotted to procedural memory, and suggest that the role of nonprocedural cognitive components should be taken into account in patient rehabilitation.     

A Measure to Target Antipoverty Policies in the European Union Regions

The reformed cohesion policy (CP), which is the major investment tool in the European Union (EU) for delivering the Europe 2020 targets, will soon make available substantial funds to improve the quality of life of the EU citizens through supporting the economic and social development of the EU’s regions and cities. Because the reformed CP has intensified the emphasis on measuring results, also with respect to reducing poverty and social exclusion, this paper is about measuring poverty to better target EU local policies. We propose a measurement of poverty at the sub-national level in the EU by means of three poverty components describing absolute poverty, relative poverty and earnings and incomes. The core data source is the cross-sectional European Statistics on Income and Living Conditions (EU-SILC) micro-data, waves 2007–2009. Data reliability at the sub-national level is statistically assessed and the regional level is described whenever possible. To calculate the poverty components, an inequality-adverse type of aggregation is applied in order to limit compensability across indicators populating a component. No aggregation is, however, performed across the three components. In the computations of income-related indicators, individual disposable income adjusted for housing costs, used as a proxy for the costs of living, is used. Poverty is confirmed to be a multi-faceted phenomenon with clear within-country variability. This variation depends on the type of region likely linked to the urbanisation level and, consequently, to the costs of living. The proposed measure may serve to better target anti-poverty measures at the local, sub-national level in the EU.