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41.
Electrical activity was recorded from single neurons in the medial prefrontal cortex of rabbits during differential Pavlovian heart rate (HR) conditioning. A heterogeneous population of cells were found, some of which showed CS-evoked increases and others CS-evoked decreases in discharge, while some cells were biphasic. A subset of cells also showed trial-related changes in discharge that were related to acquisition of the HR discrimination between the reinforced CS+ and non-reinforced CS-. Administration of the peripheral cholinergic antagonist, methylscopolamine, and the andrenergic antagonist, atenolol, either increased or decreased maintained baseline activity of many cells, but had little or no effect on the CS-evoked activity of these cells. Waveform changes also did not result from administration of these drugs. This finding suggests that CS-evoked mPFC activity is not being driven by cardiac afferent input to CNS cardiac control centers. Previous studies have shown that ibotenic acid lesions of this area greatly decreases the magnitude of decelerative heart rate conditioned responses; the latter finding, plus the results of the present study, suggest that processing of CS/US contingencies by the prefrontal cortex contributes to the acquisition of autonomic changes during Pavlovian conditioning. 相似文献
42.
How rapidly can attention move from one object to the next? Previous studies in which the dwell time paradigm was used have estimated attentional switch times of 200–500 msec, results incompatible with the search rate estimates of 25–50 msec shown in numerous visual search studies. It has been argued that dwell times are so long in the dwell time paradigm because the attentional shifts measured are unlike those used in visual search. In the present experiment, a variation of a visual search task was used, in which serial endogenous (volitional) deployments of attention were measured directly by means of a probe reaction time task. The experiment revealed a dwell time of about 250 msec, consistent with the faster estimates from other dwell time studies. This result suggests that endogenous shifts of attention may be relatively slow and that the faster attentional shifts estimated from visual search tasks may be due to the involvement of bottom-up processes. 相似文献
43.
The present experiment examined the one-target advantage (OTA) with regard to saccadic eye movements. The OTA, previously found with manual pointing responses, refers to the finding that movements are executed faster when the limb is allowed to stop on the target compared to the situation where it has to proceed and hit a second target. Using an adapted limb movement OTA task, saccades of 5 degrees and 15 degrees were made to (a) a single target (one-target), (b) one target and immediately to another target without a change in direction (two-target-extension), and (c) one target and immediately back to the start location (two-target-reversal). Unlike manual movements, the movement times for the initial saccade in the two-target-extension condition were not prolonged compared to either of the other two conditions. Moreover, this pattern of results was found for both the shorter and longer amplitude saccades. The results indicate that the OTA does not occur in the oculomotor system and therefore is not a general motor control phenomenon. 相似文献
44.
Symbolic control of visual attention: The role of working memory and attentional control settings 总被引:4,自引:0,他引:4
Pratt J Hommel B 《Journal of experimental psychology. Human perception and performance》2003,29(5):835-845
This study examined how 1 symbol is selected to control the allocation of attention when several symbols appear in the visual field. In Experiments 1-3, the critical target feature was color, and it was found that uninformative central arrows that matched the color of the target were selected and produced unintentional shifts of attention (i.e., involuntary, initiated slowly, producing long-lasting facilitatory effects). Experiment 4 tested whether such selection is the result of an attentional filter or of a competition bias due to a match of incoming information against integrated object representations stored in working memory. Here, the critical feature was shape and color was irrelevant, but matching color arrows were still selected. Thus, features of objects in working memory will bias the selection of symbols in the visual field, and such selected symbols are capable of producing unintentional shifts of attention. ((c) 2003 APA, all rights reserved) 相似文献
45.
Serotonin (5-HT) modulates numerous processes in the central nervous system that are relevant to neuropsychiatric function and dysfunction. It exerts significant effects on anxiety, mood, impulsivity, sleep, ingestive behavior, reward systems, and psychosis. Serotonergic dysfunction has been implicated in several psychiatric conditions but efforts to more clearly understand the mechanisms of this influence have been hampered by the complexity of this system at the receptor level. There are at least 14 distinct receptors that mediate the effects of 5-HT as well as several enzymes that control its synthesis and metabolism. Pharmacologic agents that target specific receptors have provided clues regarding the function of these receptors in the human brain. 5-HT is also an important modulator of neural development and several groups have employed a genetic strategy relevant to behavior. Several inactivation mutations of specific 5-HT receptors have been generated producing interesting behavioral phenotypes related to anxiety, depression, drug abuse, psychosis, and cognition. In many cases, knockout mice have been used to confirm what has already been suspected based on pharmacologic studies. In other instances, mutations have demonstrated new functions of serotonergic genes in development and behavior. 相似文献
46.
Ronald Jay Werner-Wilson Toni Schindler Zimmerman Kathrine Daniels Stephanie M. Bowling 《Contemporary Family Therapy》1999,21(4):545-550
Although the feminist critique of marriage and family therapy has been a significant part of the literature for many years, its impact has been blunted by two criticisms. The first suggests that the feminist critique lacks empirical support. The second suggests that the feminist critique promotes an alliance with women clients at the expense of men. The first criticism has been addressed in recent years. The present study examined the relationship between feminist principles and therapeutic alliance. Results suggest that feminist principles actually enhance therapeutic relationship for men clients but has no effect on therapeutic relationship for women clients.of the Marriage and Family Therapy Program 相似文献
47.
The Effect of Inhibition of Return on Lexical Access 总被引:1,自引:0,他引:1
Abstract—Inhibition of return refers to a bias against returning attention to a location or object that has been recently attended. Recent research has shown that inhibition of return can be found not only in simple detection tasks, but also in tasks requiring relatively simple discrimination judgments. The present experiments examined whether inhibition of return occurs in tasks that require complex discriminations such as lexical decision and categorization tasks. Not only was inhibition of return found in both experiments, but a greater amount of inhibition was found for low-frequency words than for high-frequency words. These findings suggest that inhibition of return not only inhibits returning attention to previously attended locations, but can also affect the processing that is required for lexical access. 相似文献
48.
Kent C. Berridge Jay Schulkin 《The Quarterly Journal of Experimental Psychology Section B: Comparative and Physiological Psychology》1989,41(2):121-138
Previous studies of natural palatability-sensitive reactions, elicited from rats by tastes, have indicated that the taste of concentrated NaCl becomes more palatable during states of body sodium depletion. A training procedure based upon “sensory preconditioning” or “irrelevant incentive” designs was used here to establish gustatory conditioned labels (quinine or citric acid) for either NaCl or fructose while rats were in a normal physiological state. Experiment 1 replicated demonstrations by others that gustatory conditioned labels for salt can attract and act as independent incentives during the salt appetite induced by sodium depletion. Experiment 2 used the taste reactivity measure to show that the enhanced palatability of the taste of NaCl transfers to produce enhanced palatability of the taste of the isolated conditioned label for salt in a state-dependent fashion. These results offer further support for the proposition that conditioned incentives not only predict hedonic events to follow, but themselves become attributed with the hedonic properties of their reinforcers. 相似文献
49.
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