Failure of acute and chronic administration of Δ9-tetrahydrocannabinol to affect the repeated acquisition of serial position responses in pigeons

Pigeons were trained to acquire a new four-response position sequence each day by pecking three response keys in a predetermined order. The key color varied after each correct response prior to food delivery. Acute administration of Γ⁹-tetrahydrocannabinol (Δ⁹-THC) up to a dose that completely eliminated responding, had no effect on total acquisition errors, or on within session patterns of error elimination. Chronic administration of Δ⁹-THC (3–10 mg/kg/day), either before or after the session for 4–7 weeks, also did not affect these error measures, although rates of responding were markedly suppressed and at times no responding occurred Discontinuation of Δ⁹-THC administration for periods of 4–6 weeks also was without effect on errors. These experiments suggest that neither acute nor chronic Δ⁹-THC produce specific effects on the repeated acquisition of serial position responses in pigeons.     

Clinical Effectiveness of the LE<Superscript>3</Superscript>AN Program: A Military Healthy Lifestyle Program

For several decades, obesity has been a major health concern within the general population of the United States as well as within the unique military population. Unlike the civilian sector, military service requires individuals to meet weight and body fat standards. In order to assist overweight military personnel return to standards, Tripler Army Medical Center initiated the LE³AN Program. LE³AN is a one-week, day-treatment, cognitive-behavioral weight management program coupled with 12 months of weekly follow-up. Baseline data was collected on 387 consecutive participants. Despite physical fitness training and required standards in each military service, the average BMIs for men and women were in the obese range, with male participants’ BMIs significantly higher than women’s (34.3 vs 31.9, p<.005). One year outcome data was collected from 167 participants, i.e. 43.2% of treatment initiators. Among participants who completed treatment, men maintained a 6.56% loss of their initial weight while women maintained a 7.35% loss. Over a quarter, 26.6%, of those who started the program (but did not complete it) maintained at least a 5% weight loss at one year, while 61.6% of treatment completers maintained 5% weight losses. The opinions expressed in this article reflect the views of the authors and not those of the Department of Defense or the U.S. Army.     

Curt Richter: psychobiology and the concept of instinct

Curt Richter is at the origins of psychobiology in the United States. For Richter the concept of instinct was central to his research. While he had diverse interests that traversed a great range of psychobiology, the concept of instinct was fundamental to his research on specific hungers and the regulation of the internal milieu. Debates about the concept of instinct would last the bulk of Richter's experimental career, culminating in an international conference a decade after the Second World War.     

The relation of patients' treatment preferences to outcome in a randomized clinical trial

Randomization procedures are performed in order to maximize the internal validity of treatment outcome studies. Objections have been made that this practice undermines the external validity of these studies because it ignores patients' treatment preferences, thereby precluding the self-selection of treatment that can occur in the community. This study used data from a multisite, double-blind, randomized, placebo-controlled trial comparing antidepressant medication to cognitive therapy for moderately to severely depressed outpatients. It compared the treatment outcomes of patients who, via randomization, received their preferred treatment versus those who did not. Although the majority of patients stated a preference for one treatment over the other, there was no significant difference in the magnitude of reduction in symptoms of depression between those who received their treatment of choice versus those who did not. These results do not provide support for the claim that the external validity of randomized controlled trials suffers from this aspect of the randomization procedure.     

A taxometric study of the Adult Attachment Interview

This study is the first to examine the latent structure of individual differences reflected in the Adult Attachment Interview (AAI; C. George, N. Kaplan, & M. Main, 1985), a commonly used and well-validated measure designed to assess an adult's current state of mind regarding childhood experiences with caregivers. P. E. Meehl's (1995) taxometric methods (i.e., MAXCOV-HITMAX) were applied to data from 504 AAIs. Analyses revealed that the variation underlying secure versus dismissing states of mind was more consistent with a dimensional than a taxonic model. (Taxometric analyses of preoccupation were indeterminate.) In addition, variation in secure adults' (n=278) reports about their early experiences revealed little evidence for qualitative groups of earned- and continuous-secures. Rather, the inferred life experiences of secure adults appeared to be distributed continuously. Findings are discussed in terms of their theoretical implications regarding the phenomenon of earned-security specifically and variation underlying secure and insecure states of mind more generally. The consequences of these analyses for AAI reliability training and coding are also explored.     

Modeling the word recognition data of Vitevitch and Luce (1998): Is it ARTful?

Vitevitch and Luce (1998) showed that the probability with which phonemes co-occur in the language (phonotactic probability) affects the speed with which words and nonwords are named. Words with high phonotactic probabilities between phonemes were named more slowly than words with low probabilities, whereas with nonwords, just the opposite was found. To reproduce this reversal in performance, a model would seem to require not merely sublexical representations, but sublexical representations that are relatively independent of lexical representations. ARTphone (Grossberg, Boardman, & Cohen, 1997) is designed to meet these requirements. In this study, we used a technique called parameter space partitioning to analyze ARTphone’s behavior and to learn if it can mimic human behavior and, if so, to understand how. To perform best, differences in sublexical node probabilities must be amplified relative to lexical node probabilities to offset the additional source of inhibition (from top-down masking) that is found at the sublexical level.     

The self-narrative and acute psychosis

The aim of this study was to apply the narrative approach in analyzing family therapy meetings in cases of acute psychosis. The self-narrative is essential in acute psychosis since it is either collapsed or not coherent enough. The results indicate that it is important to create concrete practices that produce stories concerning the patient in relation to others. The self-narrative must be re-authored by the patient even though it is socially constructed. This is achieved by creating multiple perspectives of self-narratives in so-called therapy meetings with the patient, family members, and staff members representing different professionals.     

The time course of recognition of novel melodies

Seven experiments explored the time course of recognition of brief novel melodies. In a continuous-running-memory task, subjects recognized melodic transpositions following delays up to 2.0 min. The delays were either empty or filled with other melodies. Test items included exact transpositions (T), same-contour lures (SC) with altered pitch intervals, and different-contour lures (DC). DCs differed from Ts in the pattern of ups and downs of pitch. With this design, we assessed subjects’ discrimination of detailed changes in pitch intervals (T/SC discrimination) as well as their discrimination of contour changes (T/DC). We used both artificial and “real” melodies. Artificial melodies differed in conformity to a musical key, being tonal or atonal. After empty delays, T/DC discrimination was superior to T/SC discrimination. Surprisingly, after filled delays, T/SC discrimination was superior to T/DC. When only filled delays were tested, T/SC discrimination did not decline over the longest delays. T/DC performance declined more than did T/SC performance across both empty and filled delays. Tonality was an important factor only for T/SC discrimination after filled delays. T/DC performance was better with rhythmically intact folk melodies than with artificial isochronous melodies. Although T/SC performance improved over filled delays, it did not overtake T/DC performance. These results suggest that (1) contour and pitch-interval information make different contributions to recognition, with contour dominating performance after brief empty delays and pitch intervals dominating after longer filled delays; (2) a coherent tonality facilitates the encoding of pitch-interval patterns of melodies; and (3) the rich melodic—rhythmic contours of real melodies facilitate T/DC discrimination. These results are discussed in terms of automatic and controlled processing of melodic information.     

Forest lights: Notes on the conceptualization of the unconscious

Using the metaphor of lights appearing unexplained in the night, the author argues for a conceptualization of the unconscious based on a posture of trust and acceptance rather than one of fear and explanation.His last book,Idea and Experience, dealt with Husserl's project of phenomenology inIdeas I. He has recently completed another book,The Embers and the Stars: A Philosophical Inquiry into the Moral Sense of Nature.     

Balancing the ledger: An application of Nagy's theories to the study of continuity and change among generations

This study uses an interpretive interview method to examine the micro-processes of generational continuity and change among a group of social activists. Boszormenyi-Nagy's theory of responsibility between generations, alternative models outside the family, and choice are used to explain the instances of change. Implications for research and practice are addressed.