Gender differences in memory for the appearance of others

Five studies investigated gender differences in the accurate recall of the appearance of others. The greater interpersonal orientation and interpersonal sensitivity of women were predicted to give women an advantage over men in appearance accuracy. Under both directed- and incidental-learning conditions, women more accurately recalled information concerning the appearance of their social targets than did men, participants' memory for the appearance of female targets was more accurate than it was for male targets, and neither gender was found to be a relative advantage in recalling the appearance of same-gender targets. The motivational and knowledge-based factors that might underlie a gender difference in appearance accuracy are discussed.     

Gender moderates the effects of independence and dependence desires during the social support process

This investigation examined the roles of gender and desires for independence and dependence in the support process. We assessed 118 older adults who reported needing help with at least 1 activity of daily living as a result of illness or health problems. Men with a high desire to be independent responded negatively to receiving support from their social network. Women's outcomes were generally unaffected by their independence and dependence desires. These results indicate that gender and desires for independence and dependence should be taken into account when examining the social support process, especially in men with health problems.     

Criterion-related validity of the three-factor model of psychopathy: personality, behavior, and adaptive functioning

The Psychopathy Checklist-Revised (PCL-R) has been conceptualized as indexing two distinct but correlated factors. Previous research has established that these factors demonstrate distinct patterns of relations with external criteria. However, more recent findings suggest that the PCL-R psychopathy construct may encompass three distinguishable factors, reflecting affective, interpersonal, and behavioral symptoms. Here, we evaluated the validity of this newer three-factor model of the PCL-R factors with reference to external criteria from the domains of personality, antisocial behavior; and adaptive functioning in a sample of 310 incarcerated offenders. The interpersonal factor was related to social dominance, low stress reactivity, and higher adaptive functioning; the affective factor was correlated with low social closeness and violent offending; and the behavioral factor was associated with negative emotionality, disinhibition, reactive aggression, and poor adaptive functioning. These findings provide support for the convergent and discriminant validity of these psychopathy facets.     

An analysis of independence and interactions of brain substrates that subserve multiple attributes, memory systems, and underlying processes

It is proposed that memory is organized into event-based, knowledge-based, and rule-based memory systems. Furthermore, each system is composed of the same set of multiple attributes and characterized by a set of process oriented operating characteristics that are mapped onto multiple neural regions and interconnected neural circuits. Based on this theoretical model of memory, it is possible to investigate the independence and interaction among brain regions between any two systems for any of the proposed attributes or processes. This applies also to the investigation of independence and interactions between any two attributes within a system and between processes associated with a system for any of the proposed attributes. In this article, research evidence is presented to suggest that there are both dissociations and interactions between the hippocampus and caudate nucleus in mediating spatial and response attributes within the event-based memory system, between the hippocampus and the parietal cortex in subserving the spatial attribute within the event-based and knowledge-based memory systems, and between the hippocampus and the prefrontal cortex in subserving the spatial attribute within the event-based and rule-based memory systems.     

The fragile X syndrome: from molecular genetics to neurobiology

Since the identification of the FMR1 gene basic research has been focused on the molecular characterization of the FMR1 gene product, the fragile X mental retardation protein (FMRP). Recent developments in fragile X research have provided new insights and knowledge about the physiological function of FMRP in the cell and the nerve cell in particular. Currently, compelling evidence suggests a role for FMRP in the transport/translation of dendritically localized mRNAs. In addition, the identification of some of the target mRNAs of FMRP have led to an increased interest in the neurobiology of the syndrome. This review highlights the role of FMRP in dendritic mRNA transport/translation in relation to synaptic plasticity, a molecular mechanism implicated in learning and memory.     

Evaluating Attributions for an Illness Based Upon the Name: Chronic Fatigue Syndrome, Myalgic Encephalopathy and Florence Nightingale Disease

In recent years, considerable discussion has occurred about stigma surrounding the name given to an illness currently known as chronic fatigue syndrome (CFS). Although patients and medical personnel have expressed varying opinions on this issue, no studies have evaluated how beliefs about the illness change based upon the type of name used for diagnostic purposes. Proposals have been put forth to rename the illness with an eponym (a famous patient's or researcher's name) or with a less trivial sounding, more medically based type of name. In this study, attributions about CFS were measured in three groups of medical trainees. All groups read the same case study of a person with classic symptoms of chronic fatigue syndrome, with the only difference being in the type of name given. Trainees then were asked to provide attributions about certain aspects of the illness, including its cause, severity, and prognosis. Results suggested that, across name conditions, most trainees appeared to consider the symptom complex of CFS a serious illness resulting in poor quality of life. In addition, findings indicated that the name, chronic fatigue syndrome, may be regarded less seriously than the Myalgic Encephalopathy name with respect to some important aspects of the illness. In this study, specialty of medical trainee also played a role in how the illness was perceived.     

Local synthesis of proteins at synaptic sites on dendrites: role in synaptic plasticity and memory consolidation?

Long-lasting forms of memory are thought to be mediated by modifications in synapses that are induced by particular patterns of activity, take time to be established (consolidated), and involve new gene expression. The molecular mechanisms underlying such long-lasting synaptic modifications remain to be defined. Here, we focus on new findings regarding synapse-specific gene expression and especially the intracellular transport and synaptic targeting of the mRNA for a recently identified immediate early gene called activity-regulated cytoskeleton-associated protein (Arc). Arc mRNA is transported into dendrites after episodes of neuronal activation. The newly synthesized Arc mRNA localizes selectively at synapses that have experienced particular patterns of activity, and this targeting depends on NMDA receptor activation. Arc protein is assembled into the postsynaptic junction, and Arc expression is strongly induced by brief behavioral experiences in select populations of neurons. These features of Arc induction and trafficking reveal novel cellular mechanisms that are well suited to mediate long-term synapse-specific modifications. We will review findings from other laboratories that both LTP and memory are disrupted when Arc induction is blocked, and we will discuss the possibility that Arc protein may play a key role in activity-dependent synaptic modification.     

Incremental validity of the MMPI-A content scales in the prediction of self-reported symptoms

The incremental contribution of the MMPI-A (Butcher et al., 1992) content scales to the prediction of scores on self-report measures of psychopathology was examined in a sample of 62 adolescents in inpatient treatment and 59 adolescents from the community. All participants completed the MMPI-A and a battery of criterion measures. A series of hierarchical regression analyses was conducted in which the MMPI-A clinical and content scales served as the independent variables and the criterion measures as the dependent variables. The content scales were found to have incremental validity beyond the clinical scales in predicting variance in the criterion measures. Similarly, the clinical scales also demonstrated incremental validity over the content scales in making these predictions. Both sets of scales made independent contributions to the prediction of sample membership (clinical vs. nonclinical). Findings suggest that both the clinical and content scales of the MMPI-A make significant contributions to the assessment of adolescents' psychological functioning.     

Interference to ongoing activities covaries with the characteristics of an event-based intention

Previous studies of event-based prospective memory have demonstrated that the character of an ongoing task can affect cue detection. By contrast, this study demonstrated that there is a reciprocal relationship insofar as cue-verification and response-retrieval processes interfered with making a response in the ongoing task. The amount of interference was determined by the type of intention, which was manipulated to affect the complexity of verification and retrospective response retrieval. These relationships were true even when the interference caused by cue detection was separated from a more general effect to ongoing-task performance caused by shifts in attentional allocation policies. The results have theoretical implications for models that attempt to specify the cognitive microstructure of event-based prospective memory.     

Cognitive aspects of chronic depression

Previous research on chronic depression has focused on its link with other mood disorders and Axis II personality disorders. However, there are few data examining whether the cognitive perspective applies to this condition. In this cross-sectional study, 42 outpatients with chronic depression were compared with 27 outpatients with nonchronic major depressive disorder and 24 never psychiatrically ill controls on cognitive variables thought to be related to vulnerability to depression (e.g., dysfunctional attitudes, attributional style, a ruminative response style, and maladaptive core beliefs). Both depressed groups were more elevated than a never-ill comparison group. However, chronically depressed individuals were generally more elevated on measures of cognitive variables than those with major depressive disorders even after controlling for mood state and personality disorder symptoms.