Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat

Adenosine A1 and A2A receptor agonists and antagonists have been reported to alter learning and memory. The aim of our study was to investigate the involvement of adenosinergic system in memory retrieval into posterior cingulate cortex (PCC) of Wistar rats. To clarify this question, we tested specifics agonist and antagonists of adenosine A1 and A2A receptors in rats submitted to a one-trial inhibitory avoidance task. The stimulation of adenosine A1 and A2A receptors by CPA and CGS21680, respectively, impaired memory retrieval for inhibitory avoidance task, into PCC. These findings provide behavioral evidence for the role of adenosinergic system in the memory retrieval into PCC.     

Universal sex differences in the desire for sexual variety: tests from 52 nations, 6 continents,and 13 islands

Evolutionary psychologists have hypothesized that men and women possess both long-term and short-term mating strategies, with men's short-term strategy differentially rooted in the desire for sexual variety. In this article, findings from a cross-cultural survey of 16,288 people across 10 major world regions (including North America, South America, Western Europe, Eastern Europe, Southern Europe, Middle East, Africa, Oceania, South/Southeast Asia, and East Asia) demonstrate that sex differences in the desire for sexual variety are culturally universal throughout these world regions. Sex differences were evident regardless of whether mean, median, distributional, or categorical indexes of sexual differentiation were evaluated. Sex differences were evident regardless of the measures used to evaluate them. Among contemporary theories of human mating, pluralistic approaches that hypothesize sex differences in the evolved design of short-term mating provide the most compelling account of these robust empirical findings.     

Aging and judgments of duration: Effects of task complexity and method of estimation

The effects of aging on judgments of short temporal durations were explored using the prospective paradigm and the methods of verbal estimation and production. Younger and older adults performed a perceptual judgment task at five levels of complexity for periods of 30, 60, and 120 sec. Participants either continued to perform the task for a specified interval (production) or were stopped and then verbally estimated the interval. Older adults gave shorter verbal estimates and longer productions than did younger adults. The methods of verbal estimation and production yielded approximately equal duration judgment ratios once range effects were taken into account. Task complexity had little effect. The major conclusion is that duration judgment ratios decrease from younger to older adults when the intervals are filled with a mental task.     

From chaos to new life: Ritual enactment in the passage from illness to health

Illness irreversibly alters our lives and our relationships. More than a physical or psychological experience, the passage of illness is an existential crisis that is potentially transformative for an individual and his or her loved ones. It is through ritual enactment that we can most fully experience the transformative potential of illness. Rituals are common during illness, but are underutilized for the critically-important reintegration period following acute illness, when personal, interpersonal, and communal healing must occur. Pastoral counselors and others who comfort and counsel the sick and their loved ones should encourage religious and secular ritual enactment to ease this passage.     

Gender Differences in Parent–Child Emotion Narratives

Early parent–child conversations about past emotional experiences provide a rich environment for the socialization of emotions. This study explored the role of parent and child gender in this process. Participants were 21 White, middle-class, 40- to 45-month-old children and their mothers and fathers. At separate home visits, each parent discussed with their child four specific past events during which the child experienced happiness, anger, sadness, and fear, respectively. Mothers conversed more overall, talked more about emotional aspects of the experience, and used more emotion words than did fathers. Similarly, girls talked more about emotional aspects of their experiences than did boys. Further, girls used more emotion words when discussing scary events than did boys. Most intriguingly, both mothers and fathers used more emotional utterances when discussing sad events with daughters than with sons. Parent–daughter dyads also placed emotional experiences in a more interpersonal context than did parent–son dyads. Implications for the development of gender, emotional understanding, and clinical repercussions are discussed.     

Individual differences in neonatal “imitation” fail to predict early social cognitive behaviour

The influential hypothesis that humans imitate from birth – and that this capacity is foundational to social cognition – is currently being challenged from several angles. Most prominently, the largest and most comprehensive longitudinal study of neonatal imitation to date failed to find evidence that neonates copied any of nine actions at any of four time points (Oostenbroek et al., [2016] Current Biology, 26, 1334–1338). The authors of an alternative and statistically liberal post‐hoc analysis of these same data (Meltzoff et al., [2017] Developmental Science, 21, e12609), however, concluded that the infants actually did imitate one of the nine actions: tongue protrusion. In line with the original intentions of this longitudinal study, we here report on whether individual differences in neonatal “imitation” predict later‐developing social cognitive behaviours. We measured a variety of social cognitive behaviours in a subset of the original sample of infants (N = 71) during the first 18 months: object‐directed imitation, joint attention, synchronous imitation and mirror self‐recognition. Results show that, even using the liberal operationalization, individual scores for neonatal “imitation” of tongue protrusion failed to predict any of the later‐developing social cognitive behaviours. The average Spearman correlation was close to zero, mean r_s = 0.027, 95% CI [?0.020, 0.075], with all Bonferroni adjusted p values > .999. These results run counter to Meltzoff et al.'s rebuttal, and to the existence of a “like me” mechanism in neonates that is foundational to human social cognition.     

Suppression,Repressive‐Defensiveness,Restraint, and Distress in Metastatic Breast Cancer: Separable or Inseparable Constructs?

A longstanding hypothesis links affective and behavioral inhibition with cancer incidence and progression though it does not clarify psychometric distinctions among related constructs. We hypothesized that repressive-defensiveness, suppression, restraint, and distress would be separable factors in our sample of metastatic breast cancer patients. Our results support the discriminant validity of these constructs in our total sample, and the stability over 1 year in our control group. Using factor analysis, we found 4 separate factors at our prerandomization baseline corresponding closely to hypothesized constructs. Additionally, associations in a multi-trait, multi-occasion (baseline and 1 year) matrix met each of the 3 Campbell and Fiske (1959) criteria of convergent and discriminant validity. Future research testing the links between psychological, physiological, and survival outcomes with affective inhibition in cancer patients will be clearer when informed by these distinctions.     

Trauma,personality disorders and chronic depression – the role of the conversational model of psychodynamic psychotherapy in treatment resistant depression

Objective: To report preliminary data describing the interim treatment outcome of 44 patients referred with treatment-resistant depression (TRD), comorbid personality disorders and histories of early childhood trauma using the Conversational Model (CM) of psychodynamic psychotherapy. Method: Patients (N = 44), 13 males and 31 females with long histories of depression ranging from 2 to 30 years, resistant to multiple trials of treatment, were referred by mental health practitioners, including psychiatrists. They were treated with twice weekly CM psychotherapy by multidisciplinary trainees and supervised by experienced trained clinicians. Questionnaires were administered at assessment and at 12 months to assess symptoms, functioning, self-esteem, history of trauma, personality functioning and suicidality. In this preliminary study, there was no separate control group, and patients served as their own controls. Results: Patients with TRD were found to have comorbid severe personality disorders and histories of early childhood trauma. Significant improvement in symptoms, self-esteem, functioning and suicidality was noted after 12 months. Conclusion: Patients responded with symptomatic and functional improvement to twice weekly CM therapy.     

Psychological Predictors of Neurobehavioral Symptoms in a Polytrauma Veteran Sample

Given the high prevalence of comorbid conditions found in polytrauma settings, effective screening measures are needed. Several screening tools are commonly used in polytrauma clinics within the Department of Veterans Affairs (VA). This study examined the use of three screening measures—the Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), and PTSD Checklist–Civilian Version (PCL-C)—to predict scores on the Neurobehavioral Symptom Inventory (NSI). Research suggests that the presence of mental health conditions, such as PTSD, shares a significant amount of variance with postconcussive symptoms. The investigators hypothesized that the PCL-C would be the best predictor of scores on the NSI. All subjects were administered the screening measures as part of an evaluation in an outpatient Level III polytrauma clinic. Regression analysis was used to determine which instrument might serve as the best predictor of NSI total scores. Regression analysis revealed that BAI, BDI-II, and PCL-C total scores were good predictors of NSI total scores, with the BAI accounting for the majority of the variance. Mental health conditions can account for higher scores on the NSI, and screening of other mental health conditions should be taken into account when reviewing the NSI for individuals in polytrauma settings.