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161.
Whole genome sequencing (WGS) is being used for evaluation of individuals with undiagnosed disease of suspected genetic origin. Implementing WGS into clinical practice will place an increased burden upon care teams with regard to pre-test patient education and counseling about results. To quantitate the time needed for appropriate pre-test evaluation of participants in WGS testing, we documented the time spent by our clinical research group on various activities related to program preparation, participant screening, and consent prior to WGS. Participants were children or young adults with autism, intellectual or developmental disability, and/or congenital anomalies, who have remained undiagnosed despite previous evaluation, and their biologic parents. Results showed that significant time was spent in securing allocation of clinical research space to counsel participants and families, and in acquisition and review of participant’s medical records. Pre-enrollment chart review identified two individuals with existing diagnoses resulting in savings of $30,000 for the genome sequencing alone, as well as saving hours of personnel time for genome interpretation and communication of WGS results. New WGS programs should plan for costs associated with additional pre-test administrative planning and patient evaluation time that will be required to provide high quality care.  相似文献   
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The present study investigated the role of different types of movement in affordance perception, as well as the influence of sports experience. Perception of another actor’s maximum vertical jumping height and horizontal long-jumping distance was evaluated for basketball players, soccer players, and nonplayer controls after viewing point-light representations of the actors’ movements. Perceptual reports were more accurate after jumping-related movements (walking and squatting) were viewed than after nonrelated movements (standing and twisting). Vertical jump reports were more accurate than horizontal jump reports. Basketball and soccer players demonstrated higher accuracy than did controls. This research establishes that point-light displays contain essential kinematic information sufficient to support accurate affordance perception, and athletes appear better attuned to kinematic information specifying affordances for others as a result of their sports experience.  相似文献   
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The Australian population is experiencing a rapid ageing of the population, and as such, an increased need for gerontological practitioners in the helping professions will continue to grow. Terror management theory (TMT), which was used to frame this study, posits that because of the fact that humans are aware of their own mortality, they are compelled to avoid the anxiety associated with it. Personal ageing and interaction with older adults may be reminders of the unavoidable decline and death that faces us all. The purpose of this study is to examine comfort in spending time with older adults amongst students, academic teaching staff, and practitioners in the fields of psychology and social work. We sought to determine if TMT helped predict fear of being with older adults. Ageism, contact with older adults, and known demographic factors associated with attitudes towards older adults were also examined. Hierarchical multiple regression explained nearly 46% of the variance in comfort with older adults and indicated that fear of ageing, positive ageism, negative ageism, contact with older adults, and sex were significant predictors. Educational efforts aimed at addressing beliefs about ageing and older adults may contribute to further comfort in working with older adults.  相似文献   
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The Hidden Markov Modeling approach for eye-movement data analysis is able to quantitatively assess differences and similarities among individual patterns. Here we applied this approach to examine the relationships between eye-movement patterns in face recognition and age-related cognitive decline. We found that significantly more older than young adults adopted “holistic” patterns, in which most eye fixations landed around the face center, as opposed to “analytic” patterns, in which eye movements switched among the two eyes and the face center. Participants showing analytic patterns had better performance than those with holistic patterns regardless of age. Interestingly, older adults with lower cognitive status (as assessed by the Montreal Cognitive Assessment), particularly in executive and visual attention functioning (as assessed by Tower of London and Trail Making Tests) were associated with a higher likelihood of holistic patterns. This result suggests the possibility of using eye movements as an easily deployable screening assessment for cognitive decline in older adults.  相似文献   
166.
The Rotter Incomplete Sentences Blank (RISB; Rotter, Lah, & Rafferty, 1992) is a sentence completion test intended to detect psychological maladjustment. To investigate the construct validity of the measure, we investigated what aspects of personality and psychopathology are correlated with the RISB and also tested the incremental validity of the RISB in a combined sample of clinical (n = 72) and undergraduate participants (n = 69). Interrater reliability of the RISB was good (intraclass correlation > .80). The RISB overall adjustment score discriminated between clinical and undergraduate participants, and high scores on the RISB were associated with higher negative affect, more anxiety and depression, irrational thinking, and interpersonal problems. The incremental validity of the RISB was modest, but it did explain variance in satisfaction with life and personality disorder symptoms above and beyond an extracted measure of general psychological distress. Our findings support the construct validity of the RISB.  相似文献   
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