Heart rate--QT relationships during baroreceptor stimulation with diminished autonomic influence on the ventricles. Ventricular autonomic tone and QT interval.

The shortening of the QT interval of the electrocardiogram coincident with acceleration of heart rate and vice versa has been accepted for many years as evidence that the action potential duration and hence QT are necessarily dependent on heart rate. Exceptions to this rule have been attributed to the intervention of counteracting autonomic effects. In order to test this assumption, 26 conscious dogs divided into three groups were tested during baroreceptor stimulation by a bolus injection of phenylephrine. Seventeen dogs had been used in earlier studies in which they had undergone an experimental anterior myocardial infarction with apparent full recovery. A group of those dogs underwent beta-adrenergic blockade by intravenous atenolol 30 min prior to the baroreceptor activation. To test the intactness of the baroreceptor responses in the previously infarcted dogs, a third group of nine dogs that had had no prior myocardial infarction was included. All dogs were adapted to the laboratory environment and were not sedated during experiments. Simultaneous recordings of RR, QT interval, and phasic arterial pressure were made in all dogs before and during baroreceptor stimulation. In the normal group, and the previously infarcted group that received no atenolol, baroreceptor stimulation elicited a small (8/msec), but significant prolongation of the QT associated with a nearly 50% reduction in heart rate. The QT interval of the atenolol-treated dogs, although significantly more prolonged before stimulation, remained unchanged during the reflex. The data indicate that withdrawal of ventricular sympathetic tone may prolong the QT interval, thereby confirming the role of sympathetic innervation in the control of QT.(ABSTRACT TRUNCATED AT 250 WORDS)     

Extinction instead of incubation following classical aversive conditioning in dogs.

Two dogs received a single paired classical conditioning trial, with tone CS and 12 mA shock US. Both dogs then showed a conditioned blood pressure increase in response to the nonreinforced CS, which extinguished with additional nonreinforced presentations. The CR showed spontaneous recovery four days later, but reextinguished with additional nonreinforced presentations. The results were interpreted as not supporting Eysenck's theory of "incubation" following one-trial aversive conditioning.     

Assessing the acceptability of staff management procedures to direct care and supervisory staff

Direct care and supervisory staff in five residential training programs for persons with mental retardation in North Dakota rated the acceptability of six staff management procedures. Overall, staff rated “Instructions”, “Instructions and Modeling”, “Feedback and Praise”, and “Instructions, Feedback, and Praise”, as significantly more acceptable than “Self-Management” and “Self-Management, Feedback and Praise”. There was a significant group by treatment interaction in which supervisors and direct care staff had significantly different acceptability rating for four of the six procedures. The results were further analyzed by group and implications and future research are discuessed.     

Multilevel models in developmental psychological research: Rationales and applications

The armoury of statistical techniques has recently been enhanced with the multilevel model for longitudinal data. The present article explains the multilevel model for longitudinal data to the statistically non-sophisticated reader. It shows how the model relates to the five rationales of longitudinal research, as they were put forward by Baltes and Nesselroade (1979). In addition, it shows how the model matches Wohlwill's methodology of developmental functions. To elucidate the model further, three applications are given. The applications pertain to the development of children's sleeping duration during the first 18 months of life, the effects of early hospitalization on the daily frequency of crying, and the developmental relationship between social and solitary play.     

A simple and sensitive method for monitoring running-wheel movement

A running-wheel movement-detection method is described for use with a modified 1350 Commodore mouse and a Commodore 64, is described. The movement-detection method allows for the detection of partial revolutions and direction of movement, but requires no interface equipment. The modified running wheel is discussed as a new technique that may be useful for bridging empirical and theoretical differences between free-operant and discrete-trial runway procedures.     

Perceptual restoration of a “missing” speech sound: Auditory induction or illusion?

This study investigated whether the apparent completeness of the acoustic speech signal during phonemic restoration derives from a process of auditory induction (Warren, 1984) or segregation, or whether it is an auditory illusion that accompanies the completion of an abstract phonological representation. Specifically, five experiments tested the prediction of the auditory induction (segregation) hypothesis that active perceptual restoration of an [s] noise that has been replaced with an extraneous noise would use up a portion of that noise’s high-frequency energy and consequently change the perceived pitch (timbre, brightness) of the extraneous noise. Listeners were required to compare the pitch of a target noise, which replaced a fricative noise in a sentence, with that of a probe noise preceding or following the speech. In the first two experiments, a significant tendency was found in favor of the auditory induction hypothesis, although the effect was small and may have been caused by variations in acoustic context. In the following three experiments, a larger variety of stimuli were used and context was controlled more carefully; this yielded negative results. Phoneme identification responses collected in the same experiments, as well as informal observations about the quality of the restored phoneme, suggested that restoration of a fricative phone distinct from the extraneous noise did not occur; rather, the spectrum of the extraneous noise itself influenced phoneme identification. These results suggest that the apparent auditory restoration which accompanies phonemic restoration is illusory, and that the schema-guided process of phoneme restoration does not interact with auditory processing.     

Three-space inference from two-space stimulation

Oblique contours sloping at 30° with respect to the horizontal were presented alone, in combination to form chevrons, or with a vertical line to form arrowhead or Y patterns; they were projected onto a screen in the frontal parallel plane and viewed from positions that gave viewing angles of 90° (normal to the screen’s surface), 53°, or 34°. The perceived orientation of the contours, as assessed by a movable arm that the subjects set to be parallel to the obliques, changed monotonically as a function of viewing angle. The change was as great for single obliques as for combinations of obliques within the chevron, arrowhead, and Y patterns. The results of Experiment 1 were extended in Experiment 2, in which obliques at 30° and 50° with respect to the horizontal were presented singly or in combination as chevron patterns. It is argued that the results of both experiments indicate that single two-space oblique lines are immediately interpreted as lying in three-space and that the changes in perceived orientation are a consequence of this perceptual inference.     

Perceptual selectivity for color and form

Three visual-search experiments tested whether the preattentive parallel stage can-selectively guide the attentive stage to a particular known-to-be-relevant target feature. Subjects searched multielement displays for a salient green circle that had a unique form when surrounded by green nontarget squares or had a unique color when surrounded by red nontarget circles. In the distractor conditions, a salient item in the other dimension was present as well. As an extension of earlier findings (Theeuwes, 1991), the results showed that complete top-down selectivity toward a particular feature was not possible, not even after extended and consistent practice. The results reveal that selectivity depends on the relative discriminability of the stimulus dimensions: the presence of an irrelevant item with a unique color interferes with parallel search for a unique form, and vice versa.