The influence of relative frequencies of pure and mixed stimuli on mixture suppression in taste

In experiments on saltiness suppression in NaCL-sucrose mixtures, the amount of suppression depends not only on the suppressing sucrose component in the mixture, but also on the relative frequencies of pure NaCL stimuli and mixed stimuli in the series. The observed variation of mixture suppression as a function of these frequencies can be explained by Helson’s adaptation level theory.     

The relationship of estimated comprehensibility to the rate of connected speech

The relationship between subjective estimates of the comprehensibility of connected, freerunning speech and rate of speech was investigated for each of two types of time-compressed speech: pitch-varying speeded speech and pitch-normalized compressed speech. The midpoints of the resulting functions approximated the values obtained by a previously described speechrate tracking method. For equivalent degrees of comprehensibility, rates were higher for compressed speech than for speeded speech, indicating that estimates are sensitive to the intelligibility of speech. Subjective estimates of comprehensibility of time-compressed speech provide a means of assessing the itelligibility of connected speech.     

A study of orientation errors in response to Kohs-type figures(1)

In order to elucidate the nature of the orientation errors encountered when subjects are required to reproduce Kohs-type figures, subjects drawn from a culture where such errors are reported to be relatively common were required to reproduce orientation of simple figures. It was found that the responses made in the case of square figures showed a definite drift towards a “stable” orientation; the drift observed in the case of circular stimuli was too weak to permit an unambiguous interpretation. The relevance of these data to previous data on cross-cultural differences in responses to Kohs-type stimuli is briefly examined.     

Signalled free-operant avoidance of shock by pigeons pecking a key

Two pigeons were trained to peck a key under a free-operant avoidance schedule. Then, changes in key color signalled the beginning (safe period) and the end (warning period) of the response-shock interval, with a response required to change the key color. Finally, a change in key color signalled the warning period and either a response or a shock reinstated the safe stimulus. During signalled avoidance, response rate was higher during the warning stimulus than during the safe stimulus. More responding tended to occur in the warning stimulus when it was terminated by either a response or a shock than by only a response. In either procedure, response latency during the warning stimulus was a function of the duration of the warning stimulus. In general, response and shock rate were higher during unsignalled than during signalled avoidance. When the warning stimulus was brief, the results were similar to those of unsignalled avoidance. These results confirm previous findings with pigeons, are in general agreement with data provided by other species in studies of signalled avoidance, and thereby indicate the transituationality of the key-pecking operant.     

Correctness of Kruskal's algorithms for monotone regression with ties

Kruskal has proposed two modifications of monotone regression that can be applied if there are ties in nonmetric scaling data. In this note we prove Kruskal's conjecture that his algorithms give the optimal least squares solution of these modified monotone regression problems. We also propose another (third) approach for dealing with ties.Comments by Dr. J. B. Kruskal have been most helpful.     

The role of anionic, imidic and amidic forms in structure-activity relationships. Conjugation and bacteriostatic activity in sulphonamides.

The electronic structures of anionic, imidic and amidic forms of sulphonamides were investigated and compared by means of I.R., Raman and U.V. spectroscopy. Indices reflecting the electronic situation of the common moiety p-H2N-C6H4-SO2 was a whole, although not necessarily related, physically, to any event taking place in the biological processes, were found to correlate with the in vitro bacteriostatic activity of the specific individual forms. The influence of N1-substituents both on the SO2 electronic features and on the coupling between the para amino group and the phenyl ring was discussed. It resulted that the most active chemical species, in this class of compounds, are characterized, electronically, by the most electron-rich common moiety and, in particular, by the most negative oxygens in the SO2 group and the most available (less engaged) lone-pair in the rho-amino group. These conclusions give a new settlement both to the problem of resonance and to the relation between resonance effects and bacteriostatic activity in this class of compounds.