The Burden of Dementia: A Medical and Research Perspective

Alzheimer's disease remains the most common form of dementia. Dementia symptoms vary depending on individual personality, life experience, and social and cultural influences. As dementia progresses, involvement of multi-disciplinary health care professionals is needed to manage the disease. Alzheimer research is progressing rapidly. While 5% of all Alzheimer's disease may be genetically determined, the majority is not. Susceptibility genes can reveal the risk of contracting Alzheimer's disease. Early life risk factors such as education, nutrition, and vascular disease may increase the likelihood of dementia in later life. In the United States, two acetylcholinesterase inhibitors have been approved as cognitive enhancers. Possible prevention and symptomatic treatment interventions have focused on estrogen replacement therapy, antioxidants, and anti-inflammatory medications. Research advances have improved the clinical management of dementia. Ethical implications to the patient, family, and society are multiple and remain challenging.     

Personality and Dutch Emigrants' Reactions to Acculturation Strategies

This experimental questionnaire study examined individual differences in affective and normative reactions to acculturation strategies. A sample of 265 Dutch emigrants with a dual cultural background read scenarios describing the experiences of an emigrant. Eight (4 × 2) different scenario versions were developed, each referring to 1 of 4 acculturation strategies ( Berry, 1997 ) and representing either the Frisian or the Dutch native culture. Participants reacted most positively to the integration strategy. There were no differences in reactions to Frisian or Dutch original culture. With respect to the influence of personality, as measured with the Multicultural Personality Questionnaire ( van der Zee & van Oudenhoven, 2000 ), individuals high in flexibility responded more positively to the assimilation strategy than did individuals who scored low on this dimension.