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861.
Michael H. Mesches Marino Bianchin James L. McGaugh 《Neurobiology of learning and memory》1996,66(3):324-340
The aim of these experiments was to determine whether impaired retention performance in aversively motivated tasks, induced by blockade of amygdala AMPA receptors, is due to influences on mechanisms underlying memory retrieval or to other influences on performance. Rats received either footshock escape training (1 or 10 trials), or no foot shock, in a two-compartment straight alley and bilateral intra-amygdala infusions of the AMPA receptor antagonist CNQX (0.5 μg) were subsequently administered prior to inhibitory avoidance retention testing 8 days later. The CNQX impaired, but did not block, inhibitory avoidance retention performance as indicated by the initial latencies to enter the shock compartment. The animals were then retained in the alley until they remained in the starting compartment for 100 consecutive s and entries into the shock compartment were recorded as errors. In both the controls and CNQX-treated groups, increases in amount of original training resulted in fewer errors, indicating memory for the escape training. Furthermore, regardless of the amount of original training (i.e., 0, 1, or 10 trials), CNQX-treated groups made more errors. Other experiments examined intra-amygdala CNQX effects on reactivity to footshock, locomotor activity, and anxiety. CNQX decreased reactivity to footshock, blocked shock-induced decreases in locomotor activity, and had an anxiolytic effect in an elevated plus maze comparable to that induced by midazolam (0.5 μg). These findings suggest that intra-amygdala infusions of CNQX prior to retention testing affect inhibitory avoidance retention performance following aversive training by altering locomotor activity, reducing sensitivity to footshock, and reducing anxiety. The implications of these findings for hypotheses concerning amygdala function in aversively motivated learning and memory is discussed. 相似文献
862.
863.
C. L. M. Carnrike Jr. Lance M. McCracken James E. Aikens 《Journal of clinical psychology in medical settings》1996,3(1):57-67
Some aspect of psychosocial criteria is commonly utilized by most transplant programs in assessing candidates' acceptability for transplantation. However, regardless of the assessment methodology, information obtained in pretransplant assessments may be limited given the evaluative nature of the assessment as well as the sensitive nature of the contents. Indeed, transplant candidates may present themselves in a favorable fashion, minimizing any negative traits or psychological dysfunction which they perceive might prevent transplantation. Unfortunately, there are limited data addressing the extent to which transplant candidates may present themselves in an overly positive light. This investigation surveys the prevalence of social desirability in lung transplant candidates as well as its association with self-reports of perceived stress. Further, the relationship between social desirability and interviewer ratings of transplant candidacy is examined. Subjects included 24 patients in end-stage organ failure being evaluated for lung transplant candidacy. Subjects completed the Perceived Stress Scale and a brief version of the Marlowe-Crowne Social Desirability Scale. Additionally, subjects were interviewer-rated on the Psychosocial Assessment of Candidates for Transplantation. Results indicate social desirability is a prevalent phenomenon in lung transplant candidates, with more than half of the sample scoring at or above the 84th percentile on the social desirability measure. Further, self-reports of perceived stress are moderately and inversely associated with social desirability (r=–.55,p .01). Social desirability was unrelated to interviewer-ratings of transplant candidates acceptability (r=.13,p .56). Future research might include larger samples of subjects, other organ transplant candidates, and more detailed assessments of symptom distress. 相似文献
864.
Lynn Hasher Rose T. Zacks Ellen R. Stoltzfus Michael J. Kane S. Lisa Connelly 《Psychonomic bulletin & review》1996,3(2):231-237
In two experiments, the pattern of persistence of negative priming effects across delay intervals of 500 and 2,500 msec was assessed using a within-subjects, random sequencing of delays. Neill and Valdes (1992; Neill, Valdes, Terry, & Gorfein, 1992) have argued that a within-subject experimental design is required for decay of negative priming to be seen, in contrast to results reported elsewhere (e.g., Tipper, Weaver, Cameron, Brehaut, & Bastedo, 1991) showing stable negative priming effects across delays. In neither experiment was substantial evidence of decay detected, raising questions for the notion that suppression necessarily declines across brief temporal intervals and for the assertion that episodic retrieval is the sole source of negative priming. 相似文献
865.
To obtain insight into the control of fixation duration during visual search, we had 4 subjects perform simple search tasks in which we systematically varied the discriminability of the target. The experiment was carried out under two conditions. Under the first condition (blocked), the discriminability of the target was kept constant during a session. Under the second condition (mixed), the discriminability of the target varied per trial. Under the blocked condition, fixation duration increased with decreasing discriminability. For 2 subjects, we found much shorter fixation durations in difficult trials with the mixed condition than in difficult trials with the blocked condition. Overall, the subjects fixated the target, continued to search, and then went back to the target in 5%–55% of the correct trials. In these trials, the result of the analysis of the foveal target was not used for preparing the next saccade. The results support a preprogramming model of the control of fixation duration. In a simple search task, control of fixation duration appears to be indirect. 相似文献
866.
Victor J. Perotti James T. Todd J. Farley Norman 《Attention, perception & psychophysics》1996,58(5):666-679
Four experiments investigated observers’ judgments of rigidity for different types of optical motion. The depicted structural deformations were of two types: (1) those with nonparallel image trajectories that are detectable from the first-order spatiotemporal relations between pairs of views; and (2) those with parallel image trajectories that can only be detected from higher order relations among three or more views. Patterns were composed of smooth flow fields in Experiments 1 and 3, and of wire frame figures in Experiments 2 and 4. For both types of display, the nonrigidity detectable from the first-order spatiotemporal structure of the motion sequence was much more salient than the deformation detectable only from the higher order spatiotemporal structure. These results indicate that observers’ judgments of rigidity are based primarily on a two-view analysis, but that some useful information can be obtained under appropriate circumstances from higher order spatiotemporal relations among three or more views. 相似文献
867.
Active and passive avoidance following the administration of systemic DSP4, xylamine, or p-chloroamphetamine 总被引:3,自引:0,他引:3
Groups of rats were administered either DSP4 (50 mg/kg, ip), xylamine (50 mg/kg, ip), or p-chloroamphetamine (2 X 10 mg/kg, ip), either 2 weeks or 1 week before the testing of two-way active avoidance. DSP4 and xylamine, the selective noradrenaline (NA) neurotoxins, caused a two-way avoidance impairment but p-chloroamphetamine, the selective 5-hydroxytryptamine (5-HT) neurotoxin, did not do so. Pretreatment with desipramine (20 mg/kg, ip) blocked the avoidance impairment caused by DSP4 and xylamine treatment. Neither DSP4 nor xylamine caused any alteration of passive avoidance retention. The biochemical analyses indicated severe NA, but not 5-HT, depletions in the DSP4 and xylamine conditions and drastic 5-HT, but not NA, depletions in the p-chloroamphetamine conditions. These results confirm and extend earlier findings concerning the role of NA in avoidance behavior. 相似文献
868.
869.
The purpose of this paper is to review the necessary components of a comprehensive group therapy program. The balancing between the didactic and the experiential portions, and an analysis of the selection criteria, along with the rationale for a particular sequencing of elements in the curriculum, are discussed. A line between supervision and personal therapy is drawn. The author describes the milieu necessary for a successful training program to evolve and makes suggestions for improvements. The various experiential aspects of training are presented and critically evaluated. The training situation is examined from the point of view of the faculty, the trainee and the patients involved. The author marshalls evidence indicating that personal group psychotherapy in a patient group is the preferred form for most trainees for the experiential part of the program. The paper concludes that the sharing and cohesiveness of training philosophies and methods by the faculty is a prerequisite to the success of any training program. 相似文献
870.
Sara M. Freedman James S. Phillips 《Organizational behavior and human decision processes》1985,35(3):397-416
Situational performance constraints, task interest, and pay contingencies were manipulated in a laboratory study in order to investigate the cognitive mechanisms associated with the previously observed detrimental effects of constraints on affective task reactions. It was hypothesized that feelings of task competence and self-determination would account for both the direct and the interactive effects of constraints on motivation and satisfaction. The results of the study indicated that despite the fact that participants' performance was being constrained and they were aware of these constraints, the mere presence of the constraints alone failed to result in lower levels of satisfaction or motivation on a proofreading task. Post hoc analyses suggested that the constraints, in fact, led to negative affective task reactions when they also reduced participants' feelings of competence and self-determination. Interestingly, participants' generalized locus of control was associated with such effects. Internals tended to maintain stronger feelings of competence and self-determination than externals in the presence of constraints, thereby also maintaining greater motivation and satisfaction. 相似文献