Knowledge of and Interest in Genetic Results Among Parkinson Disease Patients and Caregivers

The purpose of the study is to investigate Parkinson disease (PD) patients’ and caregivers’ knowledge of and interest in genetic testing. Gaucher disease (GD) results from recessive mutations in glucocerebrosidase (GBA). Both heterozygote GBA carriers and GD patients are at greater risk for PD. Studies regarding knowledge of and interest in genetic testing have been limited and have not offered genetic results to participants. In this study, 353 PD patients and 180 caregivers were recruited to a PD genetic study. The association between GD, GBA mutations and PD was described to participants who reported their familiarity with genetic terms, answered questions on genetic concepts, and indicated their interest in knowing if they may have GD (two GBA mutations) and other genetic information that could impact their health. Ninety-three-percent of participants were interested in receiving GBA results; however, only 51.6 % of PD participants and 55.6 % of caregivers knew that “scientists have identified genes associated with a higher risk of developing PD.” PD patients may benefit from education and genetic counseling on the implications of genetic testing.     

Use of Genetic Tests among Neurologists and Psychiatrists: Knowledge,Attitudes, Behaviors,and Needs for Training

This study explores neurologists’ and psychiatrists’ knowledge, attitudes, and practices concerning genetic tests. Psychiatrists (n?=?5,316) and neurologists (n?=?2,167) on the American Medical Association master list who had agreed to receive surveys were sent an email link to a survey about their attitudes and practices regarding genetic testing; 372 psychiatrists and 163 neurologists responded. A higher proportion of neurologists (74 %) than psychiatrists (14 %) who responded to the survey had ordered genetic testing in the past 6 months. Overall, most respondents thought that genetic tests should be performed more frequently, but almost half believed genetic tests could harm patients psychologically and considered legal protections inadequate. Almost half of neurologists (49 %) and over 75 % of psychiatrists did not have a genetics professional to whom to refer patients; those who had ordered genetic tests were more likely than those who did not do so to have access to a genetic counselor. Of respondents, 10 % had received patient requests not to document genetic information and 15 % had received inquiries about direct-to-consumer genetic testing. Neurologists reported themselves to be relatively more experienced and knowledgeable about genetics than psychiatrists. These data, the first to examine several important issues concerning knowledge, attitudes and behaviors of neurologists and psychiatrists regarding genetic tests, have important implications for future practice, research, and education.     

The Effects of Income and Skill Utilization on the Underemployed's Self‐Esteem,Mental Health,and Life Satisfaction

This longitudinal study examined the effects of underemployment on psychological well‐being (i.e., self‐esteem, mental health, and life satisfaction) using a sample of 99 unemployed and 153 reemployed individuals in South Korea. Underemployment was determined by wage and skill utilization. The results indicated that when underemployment was determined by wage change, the underemployed showed a more favorable mental health level and more life satisfaction than the unemployed. However, when determined by wage difference, the underemployed were similar to the unemployed. For skill utilization‐based underemployment, no difference was observed between the underemployed and the unemployed. The implications for future research are discussed.     

An Investigation of Religion and Spirituality of Sexual Minorities in the United States: Exploring Perceptions,Intrinsic Religiosity,and Outness to Religious Communities

We investigated how sexual minority participants in the United States (N = 217; M age = 36.36 years) viewed organized religion and their relationships with a higher power. In addition, we examined the associations between levels of outness in religious communities, internalized heterosexism (IH), intrinsic religiosity, and depression. Open-ended responses revealed that views of organized religion fell into three categories—negative (57.9%), positive (9.1%), and ambivalent (33%)—and participants reported a variety of relationships to a higher power—existing relationship (61.5%), no relationship (19%), fractured relationship (4.6%), and some who felt unsure (10.8%). Participants with greater outness to a religious community reported less IH and higher intrinsic religiosity. Also, outness to a religious community moderated the association between IH and depression, such that there was not a significant association between IH and depression for individuals with low levels of outness. However, at average to high levels of outness, there was a significant association between IH and depression.     

A virtual psychiatric ward for orientating patients admitted for the first time

Misconceptions about psychiatric wards frequently cause newly admitted mental patients to stay away from these wards despite their need for treatment. Although ward orientation is typically conducted by nurses in an attempt to help patients to adapt to the new environment, it is considered time-consuming, and the method of orientation and the explanations given may vary among different nurses. This situation calls for a more effective and standardized approach to orientating mental patients on their first admission. To this end, a computer-based interactive virtual environment was developed based on a real psychiatric ward by using virtual reality (VR) technologies. It enables the patient to navigate around to gain understanding about the ward through a virtual guided tour. The effectiveness of this VR orientation approach was investigated by a randomized controlled trial with consecutive sampling. Fifty-four Chinese participants were randomly assigned to undergo ward orientation by either using the VR-based approach or reading text-based electronic information sheets about the ward with a computer. Subjective and objective measures were obtained respectively using the Chinese version of the State-Trait Anxiety Inventory questionnaire and the heart-rate variability measurement before and after the intervention. In addition, a test on the level of understanding about the ward was administered at the end of the session. The results showed that the VR orientation approach is helpful in reducing patients' anxiety while also improving their level of understanding about the ward.     

The interaction of attention and action: From seeing action to acting on perception

We discuss evidence indicating that human visual attention is strongly modulated by the potential of objects for action. The possibility of action between multiple objects enables the objects to be attended as a single group, and the fit between individual objects in a group and the action that can be performed influences responses to group members. In addition, having a goal state to perform a particular action affects the stimuli that are selected along with the features and area of space that is attended. These effects of action may reflect statistical learning between environmental cues that are linked by action and/or the coupling between perception and action systems in the brain. The data support the argument that visual selection is a flexible process that emerges as a need to prioritize objects for action.     

Holistic versus analytic processing: Evidence for a different approach to processing of Chinese at the word and character levels in Chinese children

Among 30 Hong Kong Chinese fourth graders, sensitivities to character and word constructions were examined in judgment tasks at each level. There were three conditions across both tasks: the real condition, consisting of either actual two-character compound Chinese words or real Chinese compound characters; the reversed condition, with either the order of the two morphemes in the word or the order of the semantic and phonetic radicals in the character reversed; and the random condition, with either two morphemes randomly combined to create arbitrary nonwords or a semantic radical and a phonetic radical randomly combined using correct orthographic rules to create noncharacters. On the word level, children performed worst in the reversed condition and best with real words, whereas on the character level, children performed worst in the random condition and best in the reversed condition. Findings imply a holistic tendency toward word-level processing and an analytic approach to character-level processing in these Chinese children.     

Early maturation of frequency-following responses to voice pitch in infants with normal hearing

Neural plasticity of pitch processing mechanisms at the human brainstem, as reflected by the scalp-recorded frequency-following response (FFR) to voice pitch, has been reported for normal-hearing adults. Characteristics and maturation of such a response during the first year of life have remained unclear. The purpose of this study was to examine the characteristics of FFR to voice pitch in normal-hearing infants and to make a direct comparison with adults using the same stimulus and recording parameters. 9 infants and 9 adults were recruited. A Chinese monosyllable that mimics the English vowel /i/ with a rising pitch was used to elicit the FFR to voice pitch. The results demonstrated that infant FFRs showed slightly larger Pitch Strength but comparable Frequency Error, Slope Error, and Tracking Accuracy to those obtained from adults. Early maturation of FFRs was also observed in the infants starting from 1 to 3 mo. of age.     

Two models of unawareness: comparing the object-based and the subjective-state-space approaches

This article attempts to motivate a new approach to anti-realism (or nominalism) in the philosophy of mathematics. I will explore the strongest challenges to anti-realism, based on sympathetic interpretations of our intuitions that appear to support realism. I will argue that the current anti-realistic philosophies have not yet met these challenges, and that is why they cannot convince realists. Then, I will introduce a research project for a new, truly naturalistic, and completely scientific approach to philosophy of mathematics. It belongs to anti-realism, but can meet those challenges and can perhaps convince some realists, at least those who are also naturalists.     

A job-seeking competency model for North Korean defectors who are college students in South Korea

The purpose of this study was to develop a job-seeking competency model for North Korean defectors (NKDs) who are college students in South Korea. This study adopted the Delphi method with a panel of 17 experts, comprising of NKDs who secured their jobs successfully and South Korean field experts who have hired NKDs or assisted them with their employment. Through three Delphi rounds, 18 job-seeking competencies were identified with the definition, behavioural indicators, and competency significance. In addition, the preliminary utility of the competency model was examined. Implications of the study results and future directions for enhancing the validity and utility of the competency model are discussed.