Overt naming fMRI pre- and post-TMS: Two nonfluent aphasia patients, with and without improved naming post-TMS

Two chronic, nonfluent aphasia patients participated in overt naming fMRI scans, pre- and post-a series of repetitive transcranial magnetic stimulation (rTMS) treatments as part of a TMS study to improve naming. Each patient received 10, 1-Hz rTMS treatments to suppress a part of R pars triangularis. P1 was a ‘good responder’ with improved naming and phrase length; P2 was a ‘poor responder’ without improved naming.Pre-TMS (10 years poststroke), P1 had significant activation in R and L sensorimotor cortex, R IFG, and in both L and R SMA during overt naming fMRI (28% pictures named). At 3 mo. post-TMS (42% named), P1 showed continued activation in R and L sensorimotor cortex, R IFG, and in R and L SMA. At 16 mo. post-TMS (58% named), he also showed significant activation in R and L sensorimotor cortex mouth and R IFG. He now showed a significant increase in activation in the L SMA compared to pre-TMS and at 3 mo. post-TMS (p < .02; p < .05, respectively). At 16 mo. there was also greater activation in L than R SMA (p < .08). At 46 mo. post-TMS (42% named), this new LH pattern of activation continued. He improved on the Boston Naming Test from 11 pictures named pre-TMS, to scores ranging from 14 to 18 pictures, post-TMS (2–43 mo. post-TMS). His longest phrase length (Cookie Theft picture) improved from three words pre-TMS, to 5–6 words post-TMS.Pre-TMS (1.5 years poststroke), P2 had significant activation in R IFG (3% pictures named). At 3 and 6 mo. post-TMS, there was no longer significant activation in R IFG, but significant activation was present in R sensorimotor cortex. On all three fMRI scans, P2 had significant activation in both the L and R SMA. There was no new, lasting perilesional LH activation across sessions for this patient. Over time, there was little or no change in his activation. His naming remained only at 1–2 pictures during all three fMRI scans. His BNT score and longest phrase length remained at one word, post-TMS.Lesion site may play a role in each patient’s fMRI activation pattern and response to TMS treatment. P2, the poor responder, had an atypical frontal lesion in the L motor and premotor cortex that extended high, near brain vertex, with deep white matter lesion near L SMA. P2 also had frontal lesion in the posterior middle frontal gyrus, an area important for naming (Duffau et al., 2003); P1 did not. Additionally, P2 had lesion inferior and posterior to Wernicke’s area, in parts of BA 21 and 37, whereas P1 did not.The fMRI data of our patient who had good response following TMS support the notion that restoration of the LH language network is linked in part, to better recovery of naming and phrase length in nonfluent aphasia.     

I thought we could be friends, but ...: systematic miscommunication and defensive distancing as obstacles to cross-group friendship formation

This study examined the precursors and consequences of systematic miscommunications regarding relationship interest during intergroup interaction. Pairs of previously unacquainted same-sex students (White-White, White-Chinese, or Chinese-Chinese) engaged in a relatively intimate controlled interaction. White participants who had had little prior contact with Chinese persons were more apt to exhibit a signal-amplification bias (i.e., to perceive that their overtures had conveyed more interest than was actually the case) in intergroup as compared with intragroup exchanges. In contrast, White participants with high levels of prior contact with Chinese persons and Chinese participants did not show enhanced signal amplification in intergroup relative to intragroup exchanges. These results support our hypothesis that lack of intergroup contact experience sets the stage for miscommunications regarding friendship interest. White participants' tendency to feel that they had initially communicated more interest in being friends than their Chinese partner mediated a downward shift in their actual friendship interest over time, suggesting that signal amplification triggers defensive distancing and ultimately lowers the likelihood of cross-group friendship formation.     

In need of liberation or constraint? How intergroup attitudes moderate the behavioral implications of intergroup ideologies

This study examined how behavioral responses to ideologies prompting other- or self-focus during intergroup exchanges depend on what individuals see when they look out at an outgroup interaction partner or in toward themselves. Specifically, we predicted that the outward focus on learning about and from outgroup members encouraged by multiculturalism would benefit lower-prejudice individuals (LPs) but instead amplify the implications of negative perceptions for higher-prejudice individuals (HPs). In contrast, we predicted that the evaluative concerns and self-focus induced by anti-racism would harm LPs’ behavior by leading them to second-guess acting on positive impulses but improve HPs’ behavior by leading them to rein in unfavorable reactions. Results were generally consistent with these predictions. Color-blindness had a negative effect not moderated by prejudice. These results suggest that tailoring the ideology promoted in a specific setting to the particular individuals who will be exposed to it might enhance the effectiveness of intervention efforts.     

Improved picture naming in chronic aphasia after TMS to part of right Broca's area: an open-protocol study

Functional imaging studies with nonfluent aphasia patients have observed "over-activation" in right (R) language homologues. This may represent a maladaptive strategy; suppression may result in language improvement. We applied slow, 1 Hz repetitive transcranial magnetic stimulation (rTMS) to an anterior portion of R Broca's homologue daily, for 10 days in four aphasia patients who were 5-11 years poststroke. Significant improvement was observed in picture naming at 2 months post-rTMS, with lasting benefit at 8 months in three patients. This preliminary, open trial suggests that rTMS may provide a novel treatment approach for aphasia by possibly modulating the distributed, bi-hemispheric language network.     

Increasing well-being through teaching goal-setting and planning skills: results of a brief intervention

Many factors are known to be associated with psychological well-being. However, it is much less clear whether those factors actually cause well-being and, hence, whether there is any practical value in trying to manipulate those factors to increase well-being. The proposed study addresses both the theoretical and practical issues by testing the effectiveness of an empirically-derived, brief psychological intervention to increase well-being in a non-clinical, unselected sample. The intervention focused on developing goal setting and planning (GAP) skills, which are known to be linked to well-being, potentially have widespread effects, and are amenable to intervention. Within a quasi-experimental design, participants received three, 1-h, group sessions (Study 1) or completed the programme individually in their own time (Study 2). Those taking part in the intervention, both individually and in a group, showed significant increases in subjective well-being, compared to their respective control groups not receiving the intervention. The results provide preliminary support for the view that (a) goal setting and planning skills have a causal link to subjective well-being and (b) that such skills can be learned to enhance well-being.

Feeling Transparent: On Metaperceptions and Miscommunications

Individuals’ metaperceptions regarding how another person views them tend to be egocentrically biased by their own private self‐knowledge: They overestimate the extent to which their traits, feelings, and intentions are ‘transparent’, perceiving more congruence between their inner self and the other person's impressions than actually exists. In the present article, we examine the factors, such as self‐awareness and feelings of closeness, that increase individuals’ propensity to exaggerate their transparency to others. We also examine the interpersonal consequences of transparency overestimation and the related signal amplification bias, considering how they can reduce the likelihood of relationship formation, derail the seeking and provision of social support in ongoing relationships, and more generally lead to relational conflict. Lastly, we discuss the interventions available to reduce these biases.     

Disruptive effects of vigilance on dominant group members' treatment of outgroup members: choking versus shining under pressure

Three studies examined the hypothesis that evaluative concerns exert a disruptive effect on intimacy-building behaviors exhibited by dominant group members in intergroup interaction. The authors predicted that although evaluative concerns would lead individuals with a negative baseline response to outgroup members to shine (i.e., to exhibit warmer, more friendly behavior), such concerns would have a contrary, choking, effect on individuals with a more positive baseline response. Results were generally consistent with these hypotheses across 3 different operationalizations of evaluative concerns and regardless of whether individuals' orientation toward outgroup members was assessed in terms of prejudiced racial attitudes or racial ingroup identification. Implications for lower status group members' experience of intergroup interaction and for the prejudice-reduction process are considered.     

The extent and nature of imagery during worry and positive thinking in generalized anxiety disorder

Clients in treatment for Generalized Anxiety Disorder (GAD) were compared to a control group to assess the extent and nature of imagery during worry or while thinking about a personally relevant positive future event. Two methods were used to assess mentation and were completed in counter balanced order within the worry and positive conditions. One method assessed the occurrence of imagery by requiring participants to categorize their mentation as verbal thoughts or images every 10 s. The other method involved participants estimating the duration of any imagery that occurred in the previous 10 s. Imagery during worry occurred less often than while thinking about a positive event for both groups, but GAD clients had a more pronounced deficit of imagery during worry than the control group. Images that occurred were briefer during worry than while thinking about a positive future event and were briefer in the GAD than the control group for both worry and positive conditions. The results thus confirmed that imagery is less common during worry in clients with GAD but also demonstrated that the imagery that does occur in GAD is briefer.     

Threatened identities and interethnic interactions

This chapter adopts a social identity threat perspective to examine dynamics of interethnic interactions. We first review relevant literature regarding the conditions under which both White and ethnic minority individuals are likely to experience social identity threat within the specific context of interethnic interactions. We focus on the threat of being perceived as stereotypical of one's ethnic group, considering situation- and person-level factors that trigger the experience of such threat during interethnic interactions. Next, we offer a framework for understanding how individuals cope with social identity threat during interethnic interactions, proposing three main classes of responses: avoidance, outgroup devaluation/derogation, and behaviour modulation/regulation. We review factors that are likely to influence the adoption of one of these responses, and then consider potential implications that each type of response may have for individuals' experiences during interactions, the development of interethnic friendships, and the attenuation of prejudice.