Effects of Aging on Functional Connectivity of the Amygdala for Subsequent Memory of Negative Pictures: A Network Analysis of Functional Magnetic Resonance Imaging Data

ABSTRACT— Aging is associated with preserved enhancement of emotional memory, as well as with age-related reductions in memory for negative stimuli, but the neural networks underlying such alterations are not clear. We used a subsequent-memory paradigm to identify brain activity predicting enhanced emotional memory in young and older adults. Activity in the amygdala predicted enhanced emotional memory, with subsequent-memory activity greater for negative stimuli than for neutral stimuli, across age groups, a finding consistent with an overall enhancement of emotional memory. However, older adults recruited greater activity in anterior regions and less activity in posterior regions in general for negative stimuli that were subsequently remembered. Functional connectivity of the amygdala with the rest of the brain was consistent with age-related reductions in memory for negative stimuli: Older adults showed decreased functional connectivity between the amygdala and the hippocampus, but increased functional connectivity between the amygdala and dorsolateral prefrontal cortices. These findings suggest that age-related differences in the enhancement of emotional memory might reflect decreased connectivity between the amygdala and typical subsequent-memory regions, as well as the engagement of regulatory processes that inhibit emotional responses.     

Gaze following and gaze priming in lemurs

Although primates have often been found to co-orient visually with other individuals, members of these same species have usually failed to use co-orientation to find hidden food in object-choice experiments. This presents an evolutionary puzzle: what is the function of co-orientation if it is not used for a function as basic as locating resources? Co-orientation responses have not been systematically investigated in object-choice experiments, and requiring co-orientation with humans (as is typical in object-choice tasks) may underestimate other species’ abilities. Using an object-choice task with conspecific models depicted in photographs, we provide experimental evidence that two lemur species (Eulemur fulvus, n = 4, and Eulemur macaco, n = 2) co-orient with conspecifics. Secondly, by analysing together two measures that have traditionally been examined separately, we show that lemurs’ gaze following behaviour and ultimate choice are closely linked. Individuals were more likely to choose correctly after having looked in the same direction as the model, and thus chose objects correctly more often than chance. We propose a candidate system for the evolutionary origins of more complex gaze following: ‘gaze priming.’     

Revisiting the changing and stable properties of coping utilization using latent class growth analysis: A longitudinal investigation with soccer referees

ObjectivesThis study examined the longitudinal factor invariance of problem-focused, disengagement-focused, and seeking social support coping to provide an unbiased estimation of the mean-level and differential stability of coping with longitudinal confirmatory factor analyses with mean structure. This study also examined different patterns of longitudinal coping utilization with Latent Class Growth Modeling (LCGM).MethodSoccer referees (N = 227), aged from 15 to 53 years, completed a French version of the Ways of Coping Checklist at three times over an entire season.ResultsThe structure of the coping dimensions could be assumed longitudinally invariant. The mean-level utilization of problem-focused coping did not change significantly over the season despite the presence of test–retest instability. Both disengagement and seeking support coping utilization have significantly decreased over time while displaying moderate test–retest stability. Results of LCGM revealed that, while most referees did not change their utilization of problem-focused coping, two subgroups have respectively increased and decreased their use of problem-focused coping. Two subgroups decreased significantly their use of both disengagement-oriented and seeking support coping whereas one subgroup maintained the same level of utilization.ConclusionsResults indicated that coping utilization displayed both trait-like and state-like properties, differing for distinct subgroups of referees. This research provided further evidence for the need of moving beyond the sole reliance on traditional analyses of change to recast the trait-like versus state-like debate on coping into a more idiosyncratic-nomothetic framework.     

Infant‐holding biases in mothers and affective symptoms during pregnancy and after delivery

Several authors have reported that participants have a leftward bias when holding a newborn or young infant. Our study of mothers met before and after their infant's birth sought to ascertain whether particular combinations of affective symptoms (depression, anxiety) and holding positions (horizontal versus vertical) were related to holding‐side biases. Our results showed that (a) mothers displayed a significant leftward (71%) holding bias, (b) mothers with affective symptoms held their newborn on the right side and more frequently in the vertical position, and (c) hemispheric specialization for perceiving visual emotions had no significant effect on the holding‐side biases of new mothers. These results suggest that maternal affective symptoms have a dominant effect on the determination of holding‐side preferences, when associated with a particular holding position. Copyright © 2008 John Wiley & Sons, Ltd.     

Randomized trial of a meditation-based stress reduction program and cognitive behavior therapy in generalized social anxiety disorder

Mindfulness-based stress reduction (MBSR) has been reported to reduce anxiety in a broad range of clinical populations. However, its efficacy in alleviating core symptoms of specific anxiety disorders is not well established. We conducted a randomized trial to evaluate how well MBSR compared to a first-line psychological intervention for social anxiety disorder (SAD). Fifty-three patients with DSM-IV generalized SAD were randomized to an 8-week course of MBSR or 12 weekly sessions of cognitive-behavioral group therapy (CBGT). Although patients in both treatment groups improved, patients receiving CBGT had significantly lower scores on clinician- and patient-rated measures of social anxiety. Response and remission rates were also significantly greater with CBGT. Both interventions were comparable in improving mood, functionality and quality of life. The results confirm that CBGT is the treatment of choice of generalized SAD and suggest that MBSR may have some benefit in the treatment of generalized SAD.     

An interaction between prosody and statistics in the segmentation of fluent speech

Sensitivity to prosodic cues might be used to constrain lexical search. Indeed, the prosodic organization of speech is such that words are invariably aligned with phrasal prosodic edges, providing a cue to segmentation. In this paper we devise an experimental paradigm that allows us to investigate the interaction between statistical and prosodic cues to extract words from a speech stream. We provide evidence that statistics over the syllables are computed independently of prosody. However, we also show that trisyllabic sequences with high transition probabilities that straddle two prosodic constituents appear not to be recognized. Taken together, our findings suggest that prosody acts as a filter, suppressing possible word-like sequences that span prosodic constituents.     

The contribution of recollection and familiarity to recognition memory performance in chronic pain patients

This study examines the selective impact of chronic pain on memory functioning in a recognition task. Thirty chronic pain patients and 30 healthy control subjects performed a yes-no word recognition test. The contribution of recollection and familiarity to both groups' performance was compared by means of the Remember/Know (R/K) procedure, which distinguishes recognition based on the recollection of the encoding episode (R responses) and recognition accompanied by a feeling of familiarity (K responses). Chronic pain patients showed a decrease in recollection together with an increase in familiarity: indeed, they reported less R and more K responses than control subjects. This pattern of performance was not related to the overall recognition ability. These findings are consistent with the hypothesis of the attentional cost of chronic pain, suggesting a selective impact of chronic pain on the most attention-demanding cognitive processes, such as recollection. This study emphasises the relevance of specific procedures distinguishing the underlying components of memory functioning rather than solely global indicators.     

Psychological essentialism and the differential attribution of uniquely human emotions to ingroups and outgroups

According to the psychological essentialism perspective, people tend to explain differences between groups by attributing them different essences. Given a pervasive ethnocentrism, this tendency implies that the human essence will be restricted to the ingroup whereas outgroups will receive a lesser degree of humanity. Therefore, it is argued that people attribute more uniquely human characteristics to the ingroup than to the outgroup. The present article focuses on secondary emotions that constitute such characteristics. Study 1 showed that members of high‐ and low‐status groups attribute more positive secondary emotions to the ingroup than to the outgroup. Study 2 verified that the differential attribution extended also to negative secondary emotions. No exemplars of emotions were provided in Study 3. Instead, participants had to estimate the means of two distributions of numbers that supposedly represented characteristics of the ingroup and of the outgroup. The results of this third experiment illustrated the reluctance to attribute secondary emotions to the outgroup. The findings are discussed from the perspective of psychological essentialism. Copyright © 2001 John Wiley & Sons, Ltd.