Biphasic ERK1/2 activation in both the hippocampus and amygdala may reveal a system consolidation of contextual fear memory

There is accumulating evidences to suggest that memory consolidation in some conditions involves two waves of neuronal plastic change. Using two fear conditioning procedures in male C57BL/6J mice, we have recently shown that consolidation of the foreground contextual fear memory required two waves of ERK1/2 activation in hippocampal CA1, while consolidation of cue conditioning was only associated with the early phase of activation. The present experiment further showed that this bi-phasic pattern of ERK1/2 activation was not restricted to hippocampal CA1, but could also be observed in other fear memory-related brain areas. The unpaired conditioning procedure (context in foreground) induced two waves of ERK1/2 activation in hippocampal CA1 and CA3, as well as in the LA and BLA nuclei of the amygdala. In contrast, the paired conditioning procedure (context in background) led to a transient early phase only in hippocampal CA1 and LA. In addition, ERK1/2 phosphorylation in the hippocampus was found to correlate with that in the amygdala nuclei specifically after the unpaired procedure. Taken together, our data suggest that the observed biphasic pattern of neuronal plastic events may reflect the interplay between hippocampal and amygdala activity-dependent plasticity critical for the system consolidation of contextual fear memory.     

Problematic Internet use: clinical implications

Impulse-control disorders have received relatively little attention from the mental health community. An increasing awareness of the prevalence and impact of these disorders is emerging. Among impulse-control disorders, problematic Internet use has been considered and examined. Prevalence estimate studies indicate that problematic Internet use is experienced across geographic locations by many individuals of diverse backgrounds. This review examines problematic Internet use from epidemiological and clinical perspectives. Clinicians should be familiar with the extent of problematic Internet use and the data regarding the efficacies and tolerabilities of available treatments.     

Functional neuroimaging of autobiographical memory

Functional neuroimaging studies of autobiographical memory have grown dramatically in recent years. These studies are important because they can investigate the neural correlates of processes that are difficult to study using laboratory stimuli, including: (i) complex constructive processes, (ii) recollective qualities of emotion and vividness, and (iii) remote memory retrieval. Constructing autobiographical memories involves search, monitoring and self-referential processes that are associated with activity in separable prefrontal regions. The contributions of emotion and vividness have been linked to the amygdala and visual cortex respectively. Finally, there is evidence that recent and remote autobiographical memories might activate the hippocampus equally, which has implications for memory-consolidation theories. The rapid development of innovative methods for eliciting personal memories in the scanner provides the opportunity to delve into the functional neuroanatomy of our personal past.     

Adaptation to sensory-motor temporal misalignment: instrumental or perceptual learning?

Sensory-motor delays vary over the course of development and under different environmental conditions. Previous research has shown that humans can compensate for the resulting temporal misalignment while performing sensory-motor tasks (e.g., Cunningham, Billock, & Tsou, 2001a), but remains silent on the question of whether perceptual learning-similar to that involved in adaptation to spatial misalignment (e.g., Redding & Wallace, 1993) and in adaptation to purely intersensory misalignment (e.g., Fujisaki, Shimojo, Kashino, & Nishida, 2004)-is also involved in this adaptive response. Following an attempted replication of Cunningham et al.'s (2001a) study in a preliminary experiment, we present in this paper two experiments that demonstrate that after-effects of adaptation to temporal misalignment do not spontaneously decay. The literature on adaptation to spatial misalignment suggests that, while instrumental learning spontaneously decays in the absence of reinforcement, perceptual learning persists. Therefore our results are consistent with adaptation being effected through perceptual learning.     

Same-Sex and Other-Sex Peer Reports: Unique Contributors to Understanding Children’s School Adjustment

The present study proposed to understand how same-sex and other-sex peer nominations relate differently to teacher reports of children’s behaviors and measures of children’s friendships. Students provided peer nominations, mutual friend data, and social network data. Teachers rated students’ antisocial behavior and social competence. As expected, other-sex peer social preference scores predicted teacher ratings of antisocial behavior, while same-sex peer social preference scores predicted data on friendships and social groups. Unexpectedly, both same and other sex peer nominations predicted children’s teacher-rated social competence. Findings suggest that other-sex peers offer a unique perspective on children’s social behavior that is neither superfluous nor unimportant to understanding children’s psychosocial adjustment.     

Person-organization fit: Testing socialization and attraction-selection-attrition hypotheses

Using the socialization and attraction-selection-attrition (ASA) frameworks, this study examined the relation between employees’ work values and their organization’s values (person-organization fit). With a two year time interval, 140 respondents participated in a longitudinal study. After entry, socialization served to enhance homogeneity. The work values underwent small changes and the perception of fit with the organization grew. Despite high retention rates results confirmed the attrition effect. Results indicated that the lower the perceived match between own and organizational values at entry, the more likely it was that someone left the organization over time. We concluded that socialization as well as attrition mechanisms were present at the same time.     

Semantic and translation priming from a first language to a second and back: Making sense of the findings

The present study investigated cross-language priming effects with unique noncognate translation pairs. Unbalanced Dutch (first language [L1])-English (second language [L2]) bilinguals performed a lexical decision task in a masked priming paradigm. The results of two experiments showed significant translation priming from L1 to L2 (meisje-GIRL) and from L2 to L1 (girl-MEISJE), using two different stimulus onset asynchronies (SOAs) (250 and 100 msec). Although translation priming from L1 to L2 was significantly stronger than priming from L2 to L1, the latter was significant as well. Two further experiments with the same word targets showed significant cross-language semantic priming in both directions ( jongen [boy]-GIRL; boy-MEISJE [GIRL]) and for both SOAs. These data suggest that L1 and L2 are represented by means of a similar lexico-semantic architecture in which L2 words are also able to rapidly activate semantic information, although to a lesser extent than L1 words are able to. This is consistent with models assuming quantitative rather than qualitative differences between L1 and L2 representations.     

Passion for Driving and Aggressive Driving Behavior: A Look at Their Relationship

The purpose of the present research was to investigate the relationship between passion for driving and aggressive driving behavior in 3 studies. Study 1 examined the association between passion and aggressive driving behavior in a sample of undergraduate students. Results showed that an obsessive passion for driving was associated with aggressive driving behavior, while harmonious passion was not. Study 2 replicated these results with an ecologically valid sample of community‐dwelling drivers. Finally, Study 3 replicated the results obtained in Studies 1 and 2 in a laboratory setting using a driving simulator under controlled frustrating driving situations with judges' assessment of aggressive driving behavior. Study 3 also showed that the emotion of anger mediated the obsessive‐passion/aggressive‐driving‐behavior relationship.     

The role of motor simulation in action perception: a neuropsychological case study

Research on embodied cognition stresses that bodily and motor processes constrain how we perceive others. Regarding action perception the most prominent hypothesis is that observed actions are matched to the observer’s own motor representations. Previous findings demonstrate that the motor laws that constrain one’s performance also constrain one’s perception of others’ actions. The present neuropsychological case study asked whether neurological impairments affect a person’s performance and action perception in the same way. The results showed that patient DS, who suffers from a frontal brain lesion, not only ignored target size when performing movements but also when asked to judge whether others can perform the same movements. In other words DS showed the same violation of Fitts’s law when performing and observing actions. These results further support the assumption of close perception action links and the assumption that these links recruit predictive mechanisms residing in the motor system.