The Impact of Angelina Jolie (AJ)’s Story on Genetic Referral and Testing at an Academic Cancer Centre in Canada

In May 2013, Angelina Jolie revealed to the media that she had undergone preventive double mastectomy after testing positive for a BRCA1 gene mutation. Media coverage has been extensive, but it is not clear how such a personal story affected the public and cancer genetics clinics. We conducted a retrospective review using data from the clinical database of the Familial Cancer Program at our centre. The impact of Ms. Jolie’s story on genetic counseling referrals and the appropriateness of such referrals were assessed and reported. The number of women referred for genetic counseling increased by 90 % after 6 months and remained high one year after AJ’s story with an increase of 88 % from baseline. The number of women who qualified for genetic testing increased by 105 % after 6 months; this increase persisted but was somewhat lower after one year with an increase of 68 % from baseline. Furthermore the number of BRCA1/2 carriers identified increased by 110 % after 6 months and by 42 % after one year.The effect of Mrs. Jolie’s story persisted one year after its release; however in the latter half of the year, the hereditary cancer risk of referred women was significantly lower than initially observed. The next challenge for our health care system will not only be to meet the increased demand for cancer genetic services in our region, but also to ensure that referrals and hence use of genetic counseling resources are appropriate.     

A novel,short and easy-to-perform method to evaluate newborns’ social olfactory preferences

Animal Cognition - Humans’ early olfactory perception has been studied mainly within the framework of mother–offspring interactions and only a few studies have focused on...     

Psychological essentialism and the differential attribution of uniquely human emotions to ingroups and outgroups

According to the psychological essentialism perspective, people tend to explain differences between groups by attributing them different essences. Given a pervasive ethnocentrism, this tendency implies that the human essence will be restricted to the ingroup whereas outgroups will receive a lesser degree of humanity. Therefore, it is argued that people attribute more uniquely human characteristics to the ingroup than to the outgroup. The present article focuses on secondary emotions that constitute such characteristics. Study 1 showed that members of high‐ and low‐status groups attribute more positive secondary emotions to the ingroup than to the outgroup. Study 2 verified that the differential attribution extended also to negative secondary emotions. No exemplars of emotions were provided in Study 3. Instead, participants had to estimate the means of two distributions of numbers that supposedly represented characteristics of the ingroup and of the outgroup. The results of this third experiment illustrated the reluctance to attribute secondary emotions to the outgroup. The findings are discussed from the perspective of psychological essentialism. Copyright © 2001 John Wiley & Sons, Ltd.     

Dichotic perception and laterality in neonates

Groups of 4-day-old neonates were tested for dichotic discrimination and ear differences with the High-Amplitude-Sucking procedure. In the first experiment, dichotic speech discrimination was attested by comparison with a control group. Furthermore, among those subjects who showed a substantial recovery of sucking response at least after one of the two syllable changes, it was observed that significantly more subjects manifested a stronger reaction to a right-ear change than to a left-ear change. In the second experiment, 4-day-old neonates were tested on syllable and music timbre discrimination. The significant Stimulus Type x Ear interaction observed suggests perceptual asymmetries indicative of very precocious brain specialization.     

Premorbid behavioral and psychosocial adjustment of children with traumatic brain injury

The premorbid adjustment of 85 six- to sixteen-year-old children with traumatic brain injury was assessed by means of standardized rating forms that were completed by the children's parents and teachers. Parents and teachers were in moderate agreement when rating children's premorbid functioning. Less than 11% of the children appeared to have premorbid disturbances. Premorbid adjustment did not appear to be clearly related to injury severity or to type of injury. It is concluded that premorbid behavioral and psychosocial factors are not strongly related to the incidence of traumatic brain injury in a sample of children with predominantly relatively severe injuries.The author gratefully acknowledges the assistance of Amy Herrema, Kevin Hogeterp, and Mary Jeanne Lynch in the data collection process.     

Associative learning in baboons (Papio papio) and humans (Homo sapiens): species differences in learned attention to visual features

We examined attention shifting in baboons and humans during the learning of visual categories. Within a conditional matching-to-sample task, participants of the two species sequentially learned two two-feature categories which shared a common feature. Results showed that humans encoded both features of the initially learned category, but predominantly only the distinctive feature of the subsequently learned category. Although baboons initially encoded both features of the first category, they ultimately retained only the distinctive features of each category. Empirical data from the two species were analyzed with the 1996 ADIT connectionist model of Kruschke. ADIT fits the baboon data when the attentional shift rate is zero, and the human data when the attentional shift rate is not zero. These empirical and modeling results suggest species differences in learned attention to visual features. Received: 30 May 1998 / Accepted after revision: 13 September 1998     

Critical issues in Muslim‐Christian relations: Theoretical,practical, dialogical,scholarly

In treating some critical issues in Muslim‐Christian relations at present and in the near future I would like to say something on the basis of what may be qualified as ‘critical realism’ on the one hand and ‘constructive partnership’ on the other. My purpose here is to identify some issues with which we have to cope when we want to improve relations between Muslims and Christians for times to come.     

SOCIAL CONFORMITY AND PSYCHOLOGICAL DIFFERENTIATION12

This study examined the role of socialization experiences in the development of psychological differentiation. In each of three countries (Holland, Italy, Mexico) two villages were selected as presenting a contrasting picture with regard to degree of emphasis on conformity to family, religious and political authority. It was hypothesized that within the pair of villages in each country children from the village which stressed social conformity would tend to be more field dependent and show other signs of less developed differentiation than children from the village in which social conformity was less emphasized. In each of the six villages approximately 100 children (boys and girls, aged 9–11 and 13–15) were studied. Differentiation was assessed by a battery of tests of field-dependence-independence and the figure-drawing test. In every comparison of mean test scores between pairs of villages, in each of the three countries, children from the village in which social conformity was stressed obtained scores reflecting less differentiated functioning. Village differences were significant for every measure of differentiation in all three countries. Addition alanalyses of the data from the tests of differentiation and other tests used yielded results essentially consistent with findings from previous studies.