A rule-based expert system for music perception

We describe an expert system written in Pascal to simulate part of Lerdahl and Jackendoff’s (1983) theory of music perception. This program, a production system based on a Hearsay II architecture (Nii, 1986), illustrates a number of techniques, including program modularity, complex data structures, and simulated parallelism using operating system concepts.     

A distance-based variety of nonlinear multivariate data analysis, including weights for objects and variables

In the distance approach to nonlinear multivariate data analysis the focus is on the optimal representation of the relationships between the objects in the analysis. In this paper two methods are presented for including weights in distance-based nonlinear multivariate data analysis. In the first method, weights are assigned to the objects while the second method is concerned with differential weighting of groups of variables. When each analysis variable defines a group the latter method becomes a variable weighting method. For objects the weights are assumed to be given; for groups of variables they may be given, or estimated. These weighting schemes can also be combined and have several important applications. For example, they make it possible to perform efficient analyses of large data sets, to use the distance-based variety of nonlinear multivariate data analysis as an addition to loglinear analysis of multiway contingency tables, and to do stability studies of the solutions by applying the bootstrap on the objects or the variables in the analysis. These and other applications are discussed, and an efficient algorithm is proposed to minimize the corresponding loss function.This study is funded by The Netherlands Organization for Scientific Research (NWO) by grant nr. 030-56403 for the PIONEER project Subject Oriented Multivariate Analysis to the third author.     

Impaired Learning and Motor Behavior in Heterozygous Pafah1b1 (Lis1) Mutant Mice

Heterozygous mutation or deletion of Pafah1b1 (LIS1) in humans is associated with syndromes with type 1 lissencephaly, a severe brain developmental disorder resulting from abnormal neuronal migration. We have created Lis1 heterozygous mutant mice by gene targeting. Heterozygous mutant mice are viable and fertile, but display global organizational brain defects as a result of impaired neuronal migration. To assess the functional impact of the mutation, Lis1 heterozygous mice and their wild-type littermates were evaluated on a wide variety of behavioral tests. Lis1 mutant mice displayed abnormal hindpaw clutching responses and were impaired on a rotarod test. Lis1 heterozygous mice were also impaired in the spatial learning version of the Morris water task. Impaired motor behavior and spatial learning and memory in Lis1 mutant mice indicates that impaired neuronal migration can have functional effects on complex behavioral responses. The behavioral findings also support the use of the Lis1 mutant mice as a model from human type 1 lissencephaly.     

The relationship of marital status,spouse’s career status,and gender to salary level

The relationship of marital status, spouse’s career status, and gender to salary was examined from five different theoretical perspectives for a sample of managers and professionals in one large organization. Results showed that married individuals whose spouses did not have careers earned more than anyone except those who were divorced, controlling for age, education, type of position, job location, organizational tenure, and job tenure. Results also showed that individuals who had never been married earned the least, women earned less than men, and men with children at home earned more than men with no children at home. These findings are discussed in terms of the different theoretical perspectives, within a changing social content.     

Differential effects of massage and heelstick procedures on transcutaneous oxygen tension in preterm neonates

The present study investigated the differential effects of heelsticks and tactile-kinesthetic massage on transcutaneous oxygen tension (TcPO₂) in preterm infants. The sample was comprised of 37 stabilized preterm neonates from the Neonatal Intensive Care Unit. During the heelstick procedure, TcPO₂ significantly declined an average of 14 mmHg. When compared to the tactile-kinesthetic massage, TcPO₂ levels during the heelstick (M = 39.8) were significantly lower than during the stimulation (M = 72.8). Mean TcPO₂ levels remained clinically safe during the four massage sessions evaluated. The TcPO₂ levels during kinesthetic stimulation were somewhat more varied, and movement and pressurization of the TcPO₂ electrode were investigated as possible artifactual explanations for this phenomenon. Overall, the findings indicate that social forms of touch such as tactile-kinesthetic massage do not appear to have a medically compromising effect on TcPO₂ in the preterm neonate. These findings are evaluated in relation to the “minimal touch” policy, and implications for future handling of the stabilized preterm neonate are discussed.     

On the mean and variance of the tetrachoric correlation coefficient

Estimates of the mean and standard deviation of the tetrachoric correlation are compared with their expected values in several 2 × 2 tables. Significant bias in the mean is found when the minimum cell frequency is less than 5. Three formulas for the standard deviation are compared and guidelines given for their use.This research was performed when the first author was on leave at the University of California at Los Angeles and was supported in part by NIH Special Research Resources Grant RR-3. The second author was also supported by NIH Fellowship 5 F22 GM00328-02.