Psychological Health and Attitude Toward Christianity Among Protestant and Catholic Sixth-Form Pupils in Northern Ireland

Northern Ireland remains both one of the more religiously active and also one of the most religiously divided countries in Europe. In this context 1,093 sixth-form pupils attending Protestant schools and 1,266 sixth-form pupils attending Catholic schools (aged between 16 and 19 years) completed the abbreviated Eysenck Personality Questionnaire Revised (EPQR-A), as a measure of psychological health, alongside the Francis Scale of Attitude toward Christainity (FSAC). The findings demonstrated that a positive attitude toward Christianity was associated with neither higher nor lower neuroticism scores, but was associated in both religious communities with lower psychoticism scores. There is no evidence, therefore, to associate a positive view of Christianity with poorer levels of psychological health among adolescents in Northern Ireland, and some evidence to associate a positive view of Christianity with better levels of psychological health.     

Glucocorticoids are required for extinction of predator stress-induced hyperarousal

Background

The role of glucocorticoids in extinction of traumatic memories has not been fully characterized despite its potential as a therapeutic target for acquired posttraumatic stress disorder (PTSD). The predator stress paradigm allows us to determine whether glucocorticoids mediate the extinction of both context-dependent and context-independent fear memories.

Methods

Male C57BL/6J mice were exposed to a predator (cat) then repeatedly exposed to the predator stress context in the absence of the cat. Context-dependent (associative) fear memory was assessed as suppression of activity during re-exposure to the predator stress context without the cat (extinction trials). Context-independent fear (non-associative) was assessed seven days after extinction trials using measures of hyperarousal and anxiety-like behaviours in environments unlike the predator stress context. To assess the role of glucocorticoids, mice were injected with metyrapone (50 mg/kg) 90 min prior to extinction trials in predator stressed mice and context-dependent and context-independent fear memories were assessed. Finally, metyrapone-treated predator stressed mice were injected with corticosterone (5 or 10 mg/kg) immediately following extinction trials and context-dependent and context-independent fear memories were assessed.

Results

Repeated re-exposure to the predator stress context without the cat present extinguished context-dependent fear memory, and also reduced hyperarousal, a generalized, chronic PTSD-like symptom. We show that extinction of context-independent predator stress-induced hyperarousal is dependent on endogenous glucocorticoids during the extinction trials. Furthermore, the inhibition of extinction by metyrapone on startle amplitude was reduced by exogenous administration of corticosterone following extinction trials. Overall, these data implicate glucocorticoids in the extinction of hyperarousal, a core symptom of PTSD.     

Traveling economically through memory space: Characterizing output order in memory for serial order

How do people report the contents of short-term memory when information about order must be retained but items can be retrieved in any order? We report an experiment using an unconstrained reconstruction task in which people can report list items in any order but must place them in their correct serial positions. We found (1) a tendency to report recent items first in immediate but not in delayed reconstruction, (2) a tendency to recall temporally isolated items first, (3) a preference for forward recall order, and (4) a preference for output orders that minimize the length of the path that must be traversed through memory space during retrieval. The results constrain most current models of short-term memory in which retrieval is ballistic and is assumed to run to completion autonomously once initiated.     

Beyond verisimilitude: A linguistically invariant basis for scientific progress

This paper proposes a solution to David Miller's Minnesotan-Arizonan demonstration of the language dependence of truthlikeness (Miller 1974), along with Miller's first-order demonstration of the same (Miller 1978). It is assumed, with Peter Urbach, that the implication of these demonstrations is that the very notion of truthlikeness is intrinsically language dependent and thus non-objective. As such, truthlikeness cannot supply a basis for an objective account of scientific progress. I argue that, while Miller is correct in arguing that the number of true atomic sentences of a false theory is language dependent, the number of known sentences (under certain straightforward assumptions) is conserved by translation; degree of knowledge, unlike truthlikeness, is thus a linguistically invariant notion. It is concluded that the objectivity of scientific progress must be grounded on the fact (noted in Cohen 1980) that knowledge, not mere truth, is the aim of science.For criticism and comments I am indebted to Noretta Koertge, David Miller, and an anonymous Synthese referee.     

The Parents Matter! Program: Building a Successful Investigator-Community Partnership

We examine the issues involved in creating and maintaining a successful collaboration between university-based researchers and community members when designing and implementing the Parents Matter! Program (PMP). The roles of focus groups, community advisory boards, and community liaisons are highlighted. PMP provides an illustration of the ongoing process of collaboration between investigators and community members and the benefits and challenges of such a partnership.