Selfhood and Self-government in Women’s Religious Writings of the Early Modern Period

ABSTRACT

Some scholars have identified a puzzle in the writings of Mary Astell (1666–1731), a deeply religious feminist thinker of the early modern period. On the one hand, Astell strongly urges her fellow women to preserve their independence of judgement from men; yet, on the other, she insists upon those same women maintaining a submissive deference to the Anglican church. These two positions appear to be incompatible. In this paper, I propose a historical-contextualist solution to the puzzle: I argue that the seeming inconsistency can be dispelled through a close examination of (i) the concepts of selfhood and self-government in Anglican women’s devotional texts of the period, and of (ii) the role that these concepts play in Astell’s feminist arguments.     

Women and men in conversation: a consideration of therapists' interruptions in therapeutic discourse

Studies of day-to-day conversation have shown that interrupting can be used as a gendered means of determining both conversational topic and speaker. This paper explores the nature of interruptions in therapeutic conversations in this light. Drawing upon two recent studies of therapists' interruptions, the author offers some preliminary ideas for consideration by therapists, clinical supervisors and researchers.     

Hyperactivity and Learning Deficits in Transgenic Mice Bearing a Human Mutant Thyroid Hormone β1 Receptor Gene

Resistance to thyroid hormone (RTH) is a human syndrome mapped to the thyroid receptor β (TRβ) gene on chromosome 3, representing a mutation of the ligandbinding domain of the TRβ gene. The syndrome is characterized by reduced tissue responsiveness to thyroid hormone and elevated serum levels of thyroid hormones. A common behavioral phenotype associated with RTH is attention deficit hyperactivity disorder (ADHD). To test the hypothesis that RTH produces attention deficits and/or hyperactivity, transgenic mice expressing a mutant TRβ gene were generated. The present experiment tested RTH transgenic mice from the PV kindred on behavioral tasks relevant to the primary features of ADHD: hyperactivity, sustained attention (vigilance), learning, and impulsivity. Male transgenic mice showed elevated locomotor activity in an open field compared to male wild-type littermate controls. Both male and female transgenic mice exhibited impaired learning of an autoshaping task, compared to wild-type controls. On a vigilance task in an operant chamber, there were no differences between transgenics and controls on the proportion of hits, response latency, or duration of stimulus tolerated. On an operant go/no-go task measuring sustained attention and impulsivity, there were no differences between controls and transgenics. These results indicate that transgenic mice bearing a mutant human TRβ gene demonstrate several behavioral characteristics of ADHD and may serve a valuable heuristic role in elucidating possible candidate genes in converging pathways for other causes of ADHD.     

Nietzsche and decadence: The revaluation of morality

The creation of moralities is necessary for the enhancement of the species, yet, the assigning of values is a sign of decadence. According to Nietzsche, this is the problem of decadence with which human beings (in particular philosophers) must contend: they must place a value on life, but placing a value on life (even on one's individual life) is problematic because it involves fracturing the whole of life into pieces. The primary objective in this paper is to address Nietzsche's own battle with the problem of decadence as it applies to individuals. I will argue that in this battle, Nietzsche carried out a revaluation of decadence and transformed himself into a strong decadent. In calling himself a strong decadent, Nietzsche not only admitted to his own decadence, but also provided himself as an example for how other strong types might contend with the problem of decadence.