Heterogeneity in verbal memory: a marker of preclinical Alzheimer's disease?

Demonstrations of memory changes in those at risk for Alzheimer's disease by the presence of the APOE e4 allele have been inconsistent to date. The present study went beyond traditional analyses of central tendency (i.e., group differences on mean test scores) and also conducted distribution analyses to search for subtle cognitive differences in subgroups of normal-functioning elderly persons with the APOE e4 genotype. The results of the study revealed that (a) the e4 and non-e4 groups failed to differ in terms of their mean scores on tests of memory and verbal skills; and (b) relative to the non-e4 group, the e4 subjects had significantly greater heterogeneity of variance on the memory measures but not on fundamental verbal skills. Logistic regression analyses indicated that the discrepancy in scores on the memory measures was a significant predictor of genotype group membership (82% correct classification rate). Implications of these findings for the detection of a preclinical phase of AD are discussed.     

Impulsivity Moderates Promotive Environmental Influences on Adolescent Delinquency: A Comparison Across Family, School, and Neighborhood Contexts

The present study examined moderating effects of impulsivity on the relationships between promotive factors from family (family warmth, parental knowledge), school (school connectedness), and neighborhood (neighborhood cohesion) contexts with delinquency using data collected from N?=?2,978 sixth to eighth graders from 16 schools surrounding a major city in the Midwestern United States. More than half of the respondents were non-Caucasian (M _age ?=?12.48; 41.0 % male). Multilevel modeling analyses were conducted to take into account the clustering of the participants within schools. Impulsivity was positively associated with adolescent delinquency. Additionally, family warmth, parental knowledge, and school connectedness, but not neighborhood cohesion, were independently and inversely related to adolescent delinquency. Finally, impulsivity moderated relationships between family warmth and parental knowledge with delinquency but not relationships between school attachment and neighborhood cohesion with delinquency. Specifically, the negative relationship between family warmth and delinquency was significant for adolescents with high levels of, but not for those with below-average levels of, impulsivity. In addition, parental knowledge had a stronger association with decreased levels of delinquency for adolescents reporting higher levels of impulsivity. The moderating effects of impulsivity did not differ for males and females or for minority and non-minority participants. Findings indicate that impulsivity may have greater impact on adolescents’ susceptibility to positive family influences than on their susceptibility to promotive factors from school or neighborhood contexts. Implications for future research and practice are discussed.     

Offender interviewing in custodial settings: Understanding validity,value and veracity issues

The purpose of this scoping literature review was to identify trends regarding validity, value and veracity issues when conducting (qualitative) interviews with offenders in custodial settings. We selected for review works from electronic databases in SAGE, Springer, and Taylor and Francis by using e-journals, Google Scholar and the behavioural science database, PsycINFO. The inclusion criteria for our studies were based on whether sources addressed offender interviewing as a wellspring of information, but excluded those that focused solely on the acquisition of clinical information (at the expense of focusing on validity, value and veracity issues). We utilised the content analysis approach to identify themes/ patterns in the research findings. Key findings suggest that offenders with impression management motivations deceive and manipulate in their research interview presentations. When gathering data from inmates in custodial care settings, best practice includes cross-checking offender interview data against other sources of evidence and taking into account the context in which they are serving their sentences.     

Introduction

Phenomenology and the Cognitive Sciences -     

Cost–benefit estimates for early intensive behavioral intervention for young children with autism—general model and single state case

Clinical research and public policy reviews that have emerged in the past several years now make it possible to estimate the cost–benefits of early intervention for infants, toddlers, and preschoolers with autism or pervasive development disorder—not otherwise specified (PDD—NOS). Research indicates that with early, intensive intervention based on the principles of applied behavior analysis, substantial numbers of children with autism or PDD—NOS can attain intellectual, academic, communication, social, and daily living skills within the normal range. Representative costs from Pennsylvania, including costs for educational and adult developmental disability services, are applied in a cost–benefit model, assuming average participation in early intensive behavioral intervention (EIBI) for three years between the age of 2 years and school entry. The model applied assumes a range of EIBI effects, with some children ultimately participating in regular education without supports, some in special education, and some in intensive special education. At varying rates of effectiveness and in constant dollars, this model estimates that cost savings range from $187,000 to $203,000 per child for ages 3–22 years, and from $656,000 to $1,082,000 per child for ages 3–55 years. Differences in initial costs of $33,000 and $50,000 per year for EIBI have a modest impact on cost–benefit balance, but are greatly outweighed by estimated savings. The analysis indicates that significant cost-aversion or cost-avoidance may be possible with EIBI. © 1998 John Wiley & Sons, Ltd.     

THE EXPERIENCE OF HOME AND THE SPACE OF CITIZENSHIP

I argue that, although we are inherently intersubjective beings, we are not first or most originally “public” beings. Rather, to become a public being, that is, a citizen—in other words, to act as an independent and self‐controlled agent in a community of similarly independent and self‐controlled agents and, specifically, to do so in a shared space in the public arena—is something that we can successfully do only by emerging from our familiar, personal territories—our homes. Finding support in texts from philosophy, psychology, and the social sciences, I construe the claim that citizenship is a developed stance as a spatial issue. I conclude that a state (or, for that matter, a philosophy) that takes the human being to begin as an isolated individual agent fails to recognize the essential spatial relationships on which we depend—namely, those arising through our way of being‐at‐home in the world; and, as a result, such a stance not only misconstrues the parameters on which citizenship is itself possible but also risks developing a social situation that encourages behaviors we see in the agoraphobic—namely, the behaviors of alienated and fundamentally homeless human beings.     

Teaching Students to Interpret Religious Poetry (and to Expand their Avenues of Thinking)

Abstract. Teaching religion and theology requires interpretation of the vast corpus of religious poetry that is found in every religious tradition, but students are generally ill‐equipped to interpret this material. Therefore teachers would do well to teach the students how to interpret religious poetry. This article discusses some of the challenges of teaching this material to students and discusses techniques and exercises that have been found useful in teaching students how to navigate the terrain of religious poetry.