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821.
Innovations in clinical genetics have increased diagnosis, treatment and prognosis of inherited genetic conditions (IGCs). This has led to an increased number of families seeking genetic testing and / or genetic counselling and increased the clinical load for genetic counsellors (GCs). Keeping pace with biomedical discoveries, interventions are required to support families to understand, communicate and cope with their Inherited Genetic Condition. The Socio-Psychological Research in Genomics (SPRinG) collaborative have developed a new intervention, based on multi-family discussion groups (MFDGs), to support families affected by IGCs and train GCs in its delivery. A potential challenge to implementing the intervention was whether GCs were willing and able to undergo the training to deliver the MFDG. In analysing three multi-perspective interviews with GCs, this paper evaluates the training received. Findings suggests that MFDGs are a potential valuable resource in supporting families to communicate genetic risk information and can enhance family function and emotional well-being. Furthermore, we demonstrate that it is feasible to train GCs in the delivery of the intervention and that it has the potential to be integrated into clinical practice. Its longer term implementation into routine clinical practice however relies on changes in both organisation of clinical genetics services and genetic counsellors’ professional development.  相似文献   
822.
Australian Aboriginal and Torres Strait Islanders are overrepresented in both the prevalence and incidence of the hepatitis C (HCV). HCV knowledge has been associated with a range of positive health behaviours. HCV knowledge has previously been investigated as a single construct; however examining different knowledge domains (i.e. transmission, risk of complications, testing and treatment) separately may be beneficial. This study investigated whether having greater HCV knowledge in different domains is associated with self-reported positive health behaviours. 203 Aboriginal people living with HCV completed a survey assessing HCV knowledge, testing and care, lifestyle changes since diagnosis and treatment intent. Respondents’ knowledge was relatively high. Greater knowledge of risk of health complications was associated with undertaking more positive lifestyle changes since diagnosis. Respondents testing and treatment knowledge was significantly associated with incarceration, lifestyle changes since diagnosis and future treatment intentions. This study illustrates the importance of ensuring that knowledge is high across different HCV domains to optimise a range of positive health behaviours of Aboriginal people living with HCV. Future health promotion campaigns targeted at Aboriginal people living with HCV could benefit from broadening their focus from prevention to other domains such as testing and treatment.  相似文献   
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AI is unable to make eye‐movements and has a deficit of reflexive attention. Here, we demonstrate that despite these deficits AI exhibits inhibition of return (IOR) for peripherally cued objects and locations. These data suggest that an intact oculomotor system is not required for the generation of either object‐based or location‐based IOR and are consistent with the view that the early, facilitatory effects of peripheral cues and late IOR effects are mediated by different mechanisms.  相似文献   
826.
This study examined the effects of organizational values on employee attachment. Factor analytic results across two studies indicated that organizational values cluster into interdependent and independent factors. In Study 2, organizational values data were collected from supervisors, and identity and attachment data were collected from subordinates. As predicted, relationships involving interdependent and dependent values were contingent on employee identity. Specifically, interdependent organizational values predicted turnover cognition and organizational commitment for employees who reported strong collective identities. Independent organizational values, on the other hand, predicted the commitment of employees with strong individual identities. Implications of these results and directions for future research are discussed.  相似文献   
827.
Historically, the brainstem has been neglected as a part of the brain involved in language processing. We review recent evidence of language-dependent effects in pitch processing based on comparisons of native vs. nonnative speakers of a tonal language from electrophysiological recordings in the auditory brainstem. We argue that there is enhancing of linguistically-relevant pitch dimensions or features well before the auditory signal reaches the cerebral cortex. We propose that long-term experience with a tone language sharpens the tuning characteristics of neurons along the pitch axis with enhanced sensitivity to linguistically-relevant, rapidly changing sections of pitch contours. Though not specific to a speech context, experience-dependent brainstem mechanisms for pitch representation are clearly sensitive to particular aspects of pitch contours that native speakers of a tone language have been exposed to. Such experience-dependent effects on lower-level sensory processing are compatible with more integrated, hierarchically organized pathways to language and the brain.  相似文献   
828.
To assess domain specificity of experience-dependent pitch representation we evaluated the mismatch negativity (MMN) and discrimination judgments of English musicians, English nonmusicians, and native Chinese for pitch contours presented in a nonspeech context using a passive oddball paradigm. Stimuli consisted of homologues of Mandarin high rising (T2) and high level (T1) tones, and a linear rising ramp (T2L). One condition involved a between-category contrast (T1/T2), the other, a within-category contrast (T2L/T2). Irrespective of condition, musicians and Chinese showed larger MMN responses than nonmusicians; Chinese larger than musicians. Chinese, however, were less accurate than nonnatives in overt discrimination of T2L and T2. Taken together, these findings suggest that experience-dependent effects to pitch contours are domain-general and not driven by linguistic categories. Yet specific differences in long-term experience in pitch processing between domains (music vs. language) may lead to gradations in cortical plasticity to pitch contours.  相似文献   
829.
Revised Reinforcement Sensitivity Theory (r-RST) is a neurobiological theory of personality which has many differences compared to the original version. This highlights the need for measurement scales to reflect the revised theory. Study 1 uses exploratory and confirmatory factor analysis to develop and test new scales (the ‘Jackson-5’) which are shown to be internally reliable, have scale inter-relationships matching theory, and to have desirable construct validity properties. Study 2 compares r-RST with original RST in the prediction of delinquency and psychopathy in students. Results suggest the new scales capture the main properties of r-RST and indicate that r-RST provides a substantially different explanation of the personality basis of dysfunctional behavior compared to original RST.  相似文献   
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