Ethical challenges in the COVID-19 research context: a toolkit for supporting analysis and resolution

ABSTRACTCOVID-19 is compromising all aspects of society, with devastating impacts on health, political, social, economic and educational spheres. A premium is being placed on scientific research as the source of possible solutions, with a situational imperative to carry out investigations at an accelerated rate. There is a major challenge not to neglect ethical standards, in a context where doing so may mean the difference between life and death. In this paper we offer a rubric for considering the ethical challenges in COVID-19 related research, in the form of an ethics toolkit for global research developed at the University of Edinburgh in collaboration with more than 200 global researchers from around the world. This toolkit provides a framework to support confrontation of ethical conflicts through the integrated and iterative analysis of Place, People, Principles and Precedents, throughout the research journey. Two case analyses are offered to exemplify the utility of the toolkit as a flexible and dynamic tool to promote ethical research in the context of COVID-19.     

Negative Intrusive Thoughts and dissociation as Risk Factors for Self‐Harm

Relationships between self‐harm and vulnerability factors were studied in a general population of 432 participants, of whom 30% reported some experience of self‐harm. This group scored higher on dissociation and childhood trauma, had lower self‐worth, and reported more negative intrusive thoughts. Among the non‐harming group, 10% scored similarly to the self‐harmers on the dissociation and self‐worth scales, and engaged in potentially maladaptive behaviors that are not defined as indicating clinical self‐harm, but experienced fewer negative intrusive thoughts. This group may be at risk of future self‐harm if they begin to experience negative intrusive thoughts. If negative intrusive thoughts are playing a causal role, then therapeutic approaches tackling them may help those who are currently self‐harming.     

Inferring Sublexical Correspondences from Sight Vocabulary: Evidence from 6- and 7-year-olds

We report an experiment designed to investigate 6-to-7-year-old children's ability to acquire knowledge of sublexical correspondences between print and sound from their reading experience. A computer database containing the printed word vocabulary of children taking part in the experiment was compiled and used to devise stimuli controlled for grapheme-phoneme correspondence (GPC) frequency and rime neighbourhood consistency according to the children's reading experience. Knowledge of GPC rules and rime units was compared by asking children to read aloud three types of nonword varying in regularity of GPC and consistency of rime pronunciation. Results supported the view that children can acquire knowledge of both GPC rules and rime units from their reading experience. GPC rule strength affects the likelihood of a GPC response; rime consistency affects the likelihood of a rime response.     

Short report: Is spatial information encoded automatically in memory?

A dual-task paradigm was used to test Hasher and Zacks' (1979) hypothesis that spatial memory is automatic. Subjects saw two sets of 16 words each, the words being presented singly in random corners of a monitor screen. They were asked to remember the words and the corner in which each word was shown. In addition, subjects were given a concurrent task to perform. This task was either “easy” (counting aloud by ones) or “difficult” (counting aloud by sevens). Attention was focused either on the memory task or on the counting task. Word recognition was better when subjects carried out the easier competing counting task and when subjects concentrated mainly upon remembering the words and their positions. Contingent spatial memory was unaffected by either manipulation, supporting the hypothesis that spatial memory is automatic.     

Pascal’s Wager: a Reason to Hesitate

Philosophia - One version of Pascal’s Wager says we should commit to, or cultivate belief in, whatever religion we think is most likely to bring us eternal joy. I pose a reductio for this...     

Analytic flexibility in laboratory aggression paradigms: Relations with personality traits vary (slightly) by operationalization of aggression

Competitive reaction time tasks (CRTTs) have been used widely in social science research, but recent criticism has been directed at the flexible quantification strategies used with this methodology. A recent review suggests that over 150 different quantification strategies have been used in this literature, and there is evidence to suggest that different operationalizations can affect the results and interpretations of experiments using CRTTs. In the current investigation, we reanalyze data from four existing samples from two different sites (total N = 600) to examine how the relations between a range of personality traits and aggression vary based on how aggression is operationalized. Our results suggest that there is a modest degree of heterogeneity in effect size and direction for these relations, and that effect size and direction were most consistent for traits more generally related to lab aggression (e.g., psychopathy, low Five-Factor Model agreeableness). In addition, profile matching analyses suggest that different operationalizations yield empirical correlates that are quite similar to one another, even when quantifying absolute rather than relative similarity. These results were consistent across site, methodology, and type of sample, suggesting that these issues are likely generalizable across most labs using CRTTs. We conclude with suggestions for future directions, particularly emphasizing the need for adequately-powered samples, and for researchers to preregister a plan for how CRTT data will be analyzed.     

Preschool‐aged children's understanding of gratitude: Relations with emotion and mental state knowledge

Developmental precursors to children's early understanding of gratitude were examined. A diverse group of 263 children was tested for emotion and mental state knowledge at ages 3 and 4, and their understanding of gratitude was measured at age 5. Children varied widely in their understanding of gratitude, but most understood some aspects of gratitude‐eliciting situations. A model‐building path analysis approach was used to examine longitudinal relations among early emotion and mental state knowledge and later understanding of gratitude. Children with a better early understanding of emotions and mental states understand more about gratitude. Mental state knowledge at age 4 mediated the relation between emotion knowledge at age 3 and gratitude understanding at age 5. The current study contributes to the scant literature on the early emergence of children's understanding of gratitude.