Neurophilosophical perspectives of neuroimaging in forensic psychiatry—giving way to a paradigm shift?

Forensic psychiatry is concerned with the relationship between psychiatric abnormalities and legal violations and crimes. Due to the lack of available biological criteria, evaluation and therapy in forensic psychiatry have so far been restricted to psychosocial and mental criteria of offenders' personalities. Recent advances in neurosciences allow a closer approach to the neural correlates of personality, moral judgments and decision-making. We propose to discuss the introduction of biological criteria in the field of forensic psychiatry and to establish rules as to what extent such biological criteria will be a better and more reliable choice in judging mentally ill criminals by using all available information that can be obtained by biological means. Psychosocial and subjective criteria in forensic evaluation will be more and more accomplished by biopsychosocial and objective criteria. The responsibility of having committed a criminal act will no longer be exclusively defined by judging free and voluntary decision-making, but rather by brain-behavior relationships. What is often referred to as psychosocially determined mental processes thus could be complemented by estimating the degree of biopsychosocially determined neural processes. We conclude that such a process could contribute to a paradigm shift in forensic psychiatry, which will have profound implications for offenders, forensic psychologists and psychiatrists, the law and society in general.     

No protective effects of education during normal cognitive aging: results from the 6-year follow-up of the Maastricht Aging Study

Recent large-scale longitudinal aging studies question earlier claims that higher education protects against cognitive decline in older age. In the present study, the authors addressed this issue by determining whether educational level had an attenuating effect on the rate of cognitive change assessed with a broad range of neuropsychological tests in a community sample of 872 healthy individuals aged 49 to 81 years at baseline. The participants were followed for 6 years and were tested 3 times (at baseline and at 3 and 6 years after baseline). Results of linear mixed-model analyses showed that education had no significant effect on cognitive change over time. These results are discussed in terms of the age range of the sample, definition and range of education, cognitive measures used, length of the study and number of consecutive assessments, and confounding effect of health. The findings question the extent of the presumed protective effects of higher education on cognitive decline during normal aging.     

Aspects of Code-Specific Memory Development

We investigated the development of code specific representations of different kinds of information in long term memory. Forty second graders, 40 sixth graders and 40 adults learned the associations between 12 pictures and one position each in a 4 × 3 grid of squares, 12 pictures and 1 of 12 monosyllabic words each or 12 pictures and 1 of 12 faces. After a 3 min distractor task, a picture was presented in the retrieval phase, and the associated position, word or face had to be selected. Performance in the verbal condition improved as a function of age, while performance in the spatial condition turned out to be independent of age, and the performance in the facial condition showed a difference between both child groups and the adults. The results revealed a developmental difference of code specific representation of different kinds of information.     

An Examination of the Substance Abuse Subtle Screening Inventory‐3 Correctional Scale in a College Student Population

In this study, the authors examined the Substance Abuse Subtle Screening Inventory‐3 Correctional scale's sensitivity and specificity at detecting college students' illegal behaviors. Sensitivity was strong, but specificity was weak. Implications for counseling and suggestions for future research are included.     

Methylphenidate amplifies long-term plasticity in the hippocampus via noradrenergic mechanisms

Methylphenidate treatment is used for Attention Deficit Hyperactivity Disorder and can improve learning and memory. Previously, improvements were considered a by-product of increased attention; however, we hypothesize that methylphenidate directly alters mechanisms underlying learning and memory, and therefore examined its effects on hippocampal long-term potentiation and long-term depression. Methylphenidate enhanced both mechanisms in the absence of presynaptic changes and in a noradrenalin beta-receptor-dependent manner. These findings can explain both the improved learning and memory and decreased learning selectivity found with methylphenidate treatment and constitute the first demonstration of direct actions of methylphenidate on mechanisms implicated in cognition.     

Divine Appetites: Food Miracles,Authority and Religious Identities in the Gujarati Hindu Diaspora

Research of the Gujarati Hindu communities of the United Kingdom and New Zealand has uncovered an extraordinary diversity of belief concerning the miraculous consumption of devotional food offerings by murtis. Devotees of certain traditions have experienced these events first-hand, but many Hindus believe the process is more subtle. Others suggest that such claims are attempts to gain spiritual authority among Hindus in the diaspora, some dismiss them as simply fraudulent. This article examines the appetite of the divine and how it is understood and contested by various Gujarati Hindu traditions in the United Kingdom and in New Zealand. It will assess the significance of food miracles and how they strengthen ideas of religious identity and spiritual validity as well as their role creating a palpable tension between traditions as to who authoritatively represents Hinduism in the diaspora.     

Decision making, impulsivity and time perception

Time is an important dimension when individuals make decisions. Specifically, the time until a beneficial outcome can be received is viewed as a cost and is weighed against the benefits of the outcome. We propose that impulsive individuals experience time differently, that is with a higher cost. Impulsive subjects, therefore, overestimate the duration of time intervals and, as a consequence, discount the value of delayed rewards more strongly than do self-controlled individuals. The literature on time perception and impulsivity, however, is not clear cut and needs a better theoretical foundation. Here, we develop the theoretical background on concepts of time perception, which could lead to an empirically based notion of the association between an altered sense of time and impulsivity.     

<Emphasis Type="Italic">My Way</Emphasis> and Life’s Highway: Replies to Steward,Smilansky, and Perry

I seek to reply to the thoughtful and challenging papers by Helen Steward, Saul Smilansky, and John Perry. Steward argues that agency itself requires access to alternative possibilities; I attempt to motivate my denial of this view. I believe that her view here is no more plausible than the view (which she rejects) that it is unfair to hold someone morally responsible, unless he has genuine access to alternative possibilities. Smilansky contends that compatibilism is morally shallow, and that we can see this from the “ultimate perspective.” In reply, I explore the nature of “zooming” arguments, and I contend that even from a somewhat more detached perspective, important features that distinguish us from mere animals can be discerned (even in a causally deterministic universe). Finally, I seek to address Perry’s defense of classical compatibilism. My main objection to his form of compatbilism is that agents must be construed as having a certain kind of “baggage”—even on his own account.

Lonelier, lazier, and teased: the stigmatizing effect of body size

The authors conducted 2 studies to examine the stigmatization of the female and male body using photographic stimuli of real people. In the first study, 75 female and 55 male undergraduates rated a series of 50 photographs of women ranging in body mass index (BMI) on 3 items: gets teased, lonely, and lazy. Both male and female observers rated bodies on either side of BMI 19-20 kg/m2 higher for the gets teased and lonely items. For the lazy item, there was a clear pattern of greater stigmatization with increasing BMI. In the second study, 40 male and 40 female observers rated a series of photographs of the male body that varied in BMI and waist-to-chest ratio on the same items. Results showed that men and women judged overweight and more tubular men to be lazier, lonelier, and teased. These findings suggest that body size is an important characteristic to consider when examining body stigmatization among men and women. These results also show support for the beautiful-is-good bias.     

Sex differences in left-handedness: a meta-analysis of 144 studies

Human handedness, a marker for language lateralization in the brain, continues to attract great research interest. A widely reported but not universal finding is a greater male tendency toward left-handedness. Here the authors present a meta-analysis of k = 144 studies, totaling N = 1,787,629 participants, the results of which demonstrate that the sex difference is both significant and robust. The overall best estimate for the male to female odds ratio was 1.23 (95% confidence interval = 1.19, 1.27). The widespread observation of this sex difference is consistent with it being related to innate characteristics of sexual differentiation, and its observed magnitude places an important constraint on current theories of handedness. In addition, the size of the sex difference was significantly moderated by the way in which handedness was assessed (by writing hand or by other means), the location of testing, and the year of publication of the study, implicating additional influences on its development.