帕金森病与重症抑郁障碍两者中的抑郁及睡眠障碍特征对比

由于帕金森病早期常仅存在抑郁、睡眠障碍等非运动症状表现,其与重症抑郁障碍难以鉴别.本研究通过对帕金森病患者及重症抑郁障碍患者行汉密尔顿抑郁量表、匹兹堡睡眠指数及多导睡眠监测评定抑郁及睡眠特征,尝试发现两者之间差异,为早期鉴别及诊断帕金森病提供理论基础.     

基于利益相关者角度分析居民健康档案存在的问题及对策

居民健康档案对政府、卫生机构、居民都具有重要意义.健康档案工作开展时间不长,还存在诸多不足.主要总结其在管理、质量、利用、信息化建设、管理对象等方面存在的不足,从利益相关者角度分析影响因素,并针对政府、基层医疗卫生机构、卫生人员这三方具有较大影响力的利益相关者提出促进健康档案实施建议.     

Self‐esteem trajectories across 25 years and midlife intimate relations

Guided by a life‐span developmental systems approach, this study examined links between self‐esteem assessed over 25 years and adaptive interaction and relationship risk at midlife using data from 341 Canadian adults surveyed (or followed) from ages 18 to 43. Results showed higher self‐esteem at age 18 was associated with more adaptive interactions and lower perceived relationship risk at age 43. A more rapid increase in self‐esteem through the transition to adulthood into midlife (ages 18–43) was also associated with more frequent adaptive interactions and less relationship risk at age 43. These results held after accounting for potential confounding variables. This study is the first to demonstrate self‐esteem trajectories over a quarter century predict midlife intimate relationship functioning.     

THE FIRST ‘DESIGNER BABY’: The Role of Narratives,Cliche´s and Metaphors in the Year 2000 Media Debate

The public do not like, and we do not like the idea of designer babies (Ruth Deech, then Chair of the Human Fertilisation and Embryology Authority, quoted in The Independent, 18 October 2000). We are all on the slippery slope-the question we should be asking is: skis or crampons (Professor John Harris, The Centre for Social Ethics and Policy, University of Manchester, in an interview with Susan Johnson). LINGUISTIC AND CULTURAL GROUNDING OF THE DESIGNER BABY DEBATE In October 2000, news was released of the world’s first ‘designer baby’—Adam Nash who was born on 29 August 2000 in the United States. He was chosen as a donor for his sister Molly, who suffered with Fanconi Anaemia, which is a rare genetic disease. Without a bone marrow transplant, Molly would have died before the age of 10. A suitable donor had not been found, so her parents decided to undergo in vitro fertilization (IVF), and preimplantation genetic diagnosis (PGD) to select an embryo that would not carry the disease-causing gene and would become a brother and a donor for Molly. At the time of his birth, Adam’s cord blood was collected and later transplanted into his sister. Initial reports suggest that the treatment has been successful.     

结果预期对青少年攻击性行为的影响：中介效应与调节效应

采用攻击性问卷、关系攻击行为量表、结果预期量表、移情量表和自我控制能力问卷对720名中学生进行调查,考察了结果预期与青少年攻击性行为的关系,以及自我控制在其中的中介作用和移情在其中的调节作用。结果发现:(1)结果预期与青少年的攻击性行为(外部攻击和关系攻击)存在显著负相关;(2)自我控制在结果预期与青少年攻击性行为之间起着完全中介作用;(3)在结果预期对青少年外部攻击行为的预测中,移情发挥了调节作用。在高移情个体中,结果预期并不预测外部攻击行为,而在低移情个体中,结果预期显著地反向预测外部攻击行为;(4)自我控制在结果预期与青少年外部攻击行为之间的中介作用受到移情的调节,高水平的移情能力可以有效地缓解青少年因低自我控制而导致的高攻击性。     

慢性心力衰竭患者临床管理与评估

尽管近年来在慢性心力衰竭(CHF)的治疗方面取得了较大的进展,但CHF患者仍有较高的住院率及病死率.CHF临床实践指南的发布促进了规范化治疗.为了取得良好的医疗效果,临床医生必须对心力衰竭患者提供一系列复杂的药物治疗及严格的自我控制措施.随着医学的不断发展,出现了包括心脏再同步化起搏、左心室辅助装置或心脏移植等治疗,而这些手段常需要在对患者进行危险性评估的基础上进行.严格遵循指南并使CHF患者出院后的教育与各种支持项目相结合才能够在一定程度上减低患者的再住院率及病死率.