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1.
Developing mice were growth-retarded by underfeeding of their mothers during lactation. Control mothers were well nourished throughout. All offspring were fed ad libitum from weaning till their behaviour was tested in adulthood. The undernourished mice had weight deficits at weaning of 49% compared with controls. Nevertheless, they showed partial catch-up growth thereafter, in that their absolute weight deficits decreased between weaning and adulthood. Social behaviour observations were made on pairs of mice of the same treatment group. Previously undernourished mice were slower to start attacking one another, spent more time near or in contact with one another and did less tail-rattling than their controls. 相似文献
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Benjamin Smart 《Theoretical medicine and bioethics》2014,35(4):251-269
Identifying the necessary and sufficient conditions for individuating and classifying diseases is a matter of great importance in the fields of law, ethics, epidemiology, and of course, medicine. In this paper, I first propose a means of achieving this goal, ensuring that no two distinct disease-types could correctly be ascribed to the same disease-token. I then posit a metaphysical ontology of diseases—that is, I give an account of what a disease is. This is essential to providing the most effective means of interfering with disease processes. Following existing work in the philosophy of medicine and epidemiology (primarily Christopher Boorse; Caroline Whitbeck; Alexander Broadbent), philosophy of biology (Joseph LaPorte; D.L. Hull), conditional analyses of causation (J.L. Mackie; David Lewis), and recent literature on dispositional essentialism (Stephen Mumford and Rani Anjum; Alexander Bird), I endorse a dispositional conception of disease. Following discussion of various conceptions of disease-identity, their relations to the clinical and pathological effects of the diseases in question, and how diseases are treated, I conclude (i) that diseases should be individuated by their causes, and (ii) that diseases are causal processes best seen as simultaneously acting sequences of mutually manifesting dispositions. 相似文献
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A limiting factor in the use of virtual environments to examine perception and action is that it is dependent on the quality of the interaction. A virtual reality game (first-person viewpoint with moderate difficulty) was used to investigate the link between control and postural regulation. Postural regulation was examined using a motion capture system, and the differences that emerged as a result of the participant being a passive observer versus an active participant were evaluated using a fractal procedure: dispersion analysis. A significant interaction was found between control and health, namely, participants' postural behavior tended to be less uniform when they were sick and when they were in control of the environment. These results lead the authors to suggest that successful interaction with novel environments depends on the ability to find and consistently use appropriate control strategies. 相似文献
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Dennis E. Reidy Lauren F. Wilson Colleen A. Sloan Amy M. Cohn Laura M. Smart Amos Zeichner 《Personality and individual differences》2013
Psychopathy is associated with emotional dysfunction that impedes the experience of emotions such as fear and sadness and has been purported to facilitate violent behavior. However, findings relative to the association between psychopathy and anger have not been reliably substantiated. Theorists have proposed that psychopathy predisposes one to experience greater frustration and anger, whereas other experts have suggested that there is no convincing evidence for this assertion. In the present study, we tested the relationship between psychopathy subfactors and anger subsequent to conflict or non-conflict interactions. Sixty-eight collegiate-men completed the Self-Report Psychopathy Scale and read vignettes depicting either a conflict or non-conflict scenario and were asked to imagine themselves in the situation. Following presentation of the vignettes, participants completed a lexical-decision-task assessing affective states. Results indicated that the psychopathy subfactors demonstrated strong differential associations, where Factor 1 showed negative and Factor 2 showed positive association with anger activation in response to interpersonal conflict. Findings are discussed in terms of the importance of anger as a facilitator of violence in some psychopathic individuals. 相似文献
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Laura Smart Richman Laura D. Kubzansky Joanna Maselko Leland K. Ackerson Mark Bauer 《Psychology & health》2013,28(8):919-932
Past measurement of vitality has included both emotional and physical components. Since aspects of physical vitality such as fatigue can be indicative of physical illness, the usefulness of existing measures of vitality to predict health is limited. This research was designed to examine the psychometric properties of a new Mental Vitality Scale and to test its associations with measures of cardiovascular health over the course of 2 years. The measure of mental vitality was administered in a two-part study using three different samples. In part 1, the reliability and validity of the scale was assessed with a student and a clinic sample. In part 2, medical data on mental and physical health were abstracted over a two-year period from 1041 patient records from a multi-specialty medical practice, and mental vitality assessed through a mailed questionnaire. The findings indicate that the Mental Vitality Scale is a valid and reliable questionnaire for measuring this construct. Mental vitality was also associated with reduced odds of several cardiovascular outcomes and prospective analyses suggest that mental vitality may serve a protective function in the development of cardiovascular disease. The results lend support for the importance of mental vitality as a construct that may be relevant for considering resilience in relation to cardiovascular disease. 相似文献
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John C Smart 《Journal of Vocational Behavior》1975,6(3):337-347
This paper examined differences in the degree to which fifteen specific sources of job satisfaction were related to and predictive of the overall satisfaction of department chairmen in the six model environments proposed by Holland (1973). The fifteen specific sources of job satisfaction were regressed on overall satisfaction, separately for chairmen in each environment, through the use of incremental stepwise multiple regression procedures. The results indicated that the overall satisfaction of chairmen in these six environments was differentially related to unique weightings and combinations of the fifteen predictor variables. It was concluded that environments, composed of essentially similar groups of people in different organizations, serve as job satisfaction reinforcer systems in a manner similar to organizations as illustrated by Dawis. 相似文献
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Archbishop Wulfstan of York (d. 1023) stands as one of the most powerful churchmen of his age. His sermons, law-codes, and political tracts are carefully crafted pieces of rhetorical power, albeit often prone to exergasia, anaphora, and epiphora. They are excellent examples of the quality and power of episcopal prose in the eleventh century, and the very real concerns facing the Anglo-Saxon realm. Beyond the enduring appeal and colourful flavour of his writings, it is possible to see a very determined effort to demand from the lay population a large number of payments for the service of the Church. Whilst this may appear a rather narrow-minded focus, certainly in a time of war and invasion, it will be argued here that for Wulfstan they offered a vehicle by which disaster could be averted, society could be aligned along proper Christian lines, and the nation itself could be saved. 相似文献