肿瘤同步放化疗合理应用的思考

同步放化疗的疗效明显优于单一放化疗和序贯放化疗,但毒副作用的叠加效应可引起严重的并发症,甚至造成死亡.本文从同步放化疗的作用机制和临床实践出发,通过对疗效与毒副作用之间的辩证关系进行具体分析,探讨了如何制定合理的肿瘤治疗决策.     

特质性与情境性成就目标定向对目标调节的影响

将209名初中生被试分为掌握、表现-接近与表现-回避三种特质性成就目标定向,随机分配在掌握定向与表现定向这两种情境性成就目标要求之下,依次阅读一系列10个同质性材料并回答一道位于每段材料之后并与该材料首句信息相关的选择题,根据被试完成每次任务的阅读时间与答题正确率,考察被试的实际目标定向以及目标调节变化过程。结果表明,特质性成就目标定向对学业成绩具有显著的预测作用,但在特定任务情境下,情境性目标要求掩盖了特质性目标的作用,而且,情境性表现目标的被试比情境性掌握目标的被试更快地调节目标以适应实验任务所隐含的实际目标线索。     

Spatial Semantics,Cognition, and Their Interaction: A Comparative Study of Spatial Categorization in English and Korean

This study has two goals. First, we present much‐needed empirical linguistic data and systematic analyses on the spatial semantic systems in English and Korean, two languages that have been extensively compared to date in the debate on spatial language and spatial cognition. We conduct our linguistic investigation comprehensively, encompassing the domains of tight‐ and loose‐fit as well as containment and support relations. The current analysis reveals both cross‐linguistic commonalities and differences: From a common set of spatial features, each language highlights a subset of those features for its principal categorization, and those primary features are importantly different between English and Korean: English speakers categorize events predominantly by containment and support relations (and do so with prepositions), whereas Korean speakers categorize them by tight‐fit and loose‐fit relations (and do so with verbs), with a further distinction of containment and support within the loose‐fit relation. The analysis also shows that the tight‐fit domain is more cross‐linguistically diverse in categorization than is the loose‐fit domain. Second, we test the language data against the nonlinguistic categorization results reported in Choi and Hattrup (2012). The results show a remarkable degree of convergence between the patterns predicted from the current linguistic analysis and those found in C&H's nonlinguistic study and thus provide empirical and strong evidence for an influence of language on nonlinguistic spatial cognition. At the same time, the study reveals areas where the two systems closely interact with each other as well as those where one is independent from the other. Taking both parts of the study together, we identify the specific roles that language and spatial perception/cognition play in spatial categorization.     

反馈相关负波：一种抑郁症的生物标记物

反馈相关负波(feedback-related negativity, FRN)是一种反映个体奖赏敏感性的脑电成分; 而抑郁症患者的特征之一是奖赏敏感性的减弱。大量横向研究发现了重度抑郁症患者(major depressive disorder, MDD)及有患抑郁症风险群体的FRN异常; 另外, 纵向研究发现FRN的异常能够预测青春期抑郁发作及抑郁症状发展, 压力、睡眠等因素在其中起调节作用。这提示FRN可能在对抑郁症的诊断及分型、抑郁高危群体的筛查及干预等方面具有潜在价值。目前关于FRN的心理功能依然存在一些争议, 在未来的研究中应该进一步明确FRN的功能和测量方法, 并探明抑郁症的异质性和共病对FRN的作用, 也应关注老年人群体中FRN与抑郁症的关系。     

天道、心性与现象学之道学转向——评张祥龙《儒家哲学史讲演录》中的心学论述

本文关注的是现象学运动在面对中国哲学传统时所发生的"道学转向"。张祥龙教授在新著《儒家哲学史讲演录》中,将这一转向推进到一个新阶段。本文试图在阐述张祥龙思想转变、新著贡献的基础上,讨论此书为当前中国哲学的创发带来的新契机。首先,祥龙教授思想的突转尤其体现在不再以海德格尔哲学为支配性的思想基源,而是将重心转向儒家传统,呈显为糅合唯识学的后现象学哲学,进而将现象学的道学转向带到心性、伦理阶段。其次,这一"心性-天道之路"结晶在《儒家哲学史讲演录》中的心学论述中。张祥龙在"时机化"学说的照应下,既会通儒佛,又指点出儒佛分际。其心学有三大贡献:道术上对"儒瑜伽"的总结;道学上对"赤子之心""孝悌慈"的阐发;道统上对罗近溪正统地位的发现与肯定。然而,在张祥龙道路所抵达的地方,仍可进一步追问比伦理转向更本源的道学转向的可能。伦理转向的真正完成需首先解悟"道体"。     

The Effects of Extrinsic Motivation on Scientific and Artistic Creativity among Middle School Students

The present study tested the effects of extrinsic motivation on scientific and artistic creativity among Chinese middle school students. In Study 1, a between-groups design was applied to examine the effects of expected rewards on scientific and artistic creativity among 123 students, and in Study 2 the same design was applied to examine the effects of expected evaluation from different raters on scientific and artistic creativity among 120 students. We also considered the effects of grade and gender in both studies. The results of Study 1 indicated that expected material reward had significant negative effects on scientific creativity for 7th graders, while expected social reward had significant positive effects on scientific creativity for 8th graders, and both expected material and social rewards had significant positive effects on artistic creativity. The results of Study 2 indicated that expected evaluation from teachers and classmates had significant negative effects on scientific creativity and significant positive effects on artistic creativity. These results suggest that there is no one-size-fits-all answer to the effects of extrinsic motivation and creativity, Factors such as culture, type of extrinsic motivation, grade, and domains of creativity must be fully considered when cultivating adolescents’ creativity.     

社会逆境感知对大学生攻击行为的影响:反刍思维与领悟社会支持的作用

为探讨社会逆境感知对大学生攻击行为的影响机制,选取577名大学生为被试,采用社会逆境感知问卷、大学生攻击行为量表、反刍思维量表及领悟社会支持量表进行测试。结果表明：（1）社会逆境感知对大学生攻击行为有显著的正向影响,并间接地通过反刍思维对大学生攻击行为产生作用;（2）领悟社会支持在社会逆境感知对大学生反刍思维的影响中起显著的调节作用,具体而言,在低领悟社会支持水平下,社会逆境感知对大学生反刍思维的预测作用更强,而在高领悟社会支持水平下,社会逆境感知对大学生反刍思维的预测作用不显著。     

改造自然界与人的道德责任——论对世界存在和人存在的重新开启

长期以来,人们总是将改造自然界的实践活动理解为满足人的生存需要的手段,在马克思以前从来没有人将改造自然界的实践活动视为一种先行开启世界存在和人存在的本体论的目的性活动。正是对改造自然界实践活动的这一重大误读,导致了现代性的实践活动给自然界带来巨大破坏和对人的存在的严重扭曲。因此,正本清源,还改造自然界实践活动的本来面目,成为摆在理论工作者面前一项迫在眉睫的任务。改造自然界的实践活动是创造世界和创造人的本体,它的先行存在地位决定了它才真正是人们对自然环境负道德责任的形而上学根据,正是通过它才开启出世界的存在和人的存在,因而它才有资格成为道德责任的关怀对象。改造自然界实践活动的先在性,决定了人们怎样进行改造自然界的实践活动,就有怎样的世界存在和怎样的人性。道德上负责任地进行改造自然界的实践活动,意味着人要负责任地创造世界、负责任地创造人的存在。对改造自然界的实践活动负道德责任,就是对自然世界负道德责任、对人本身负道德责任。