癌蛋白促凋亡现象引发的思考

肿瘤生物学中一个矛盾现象是:曾经被认为促进肿瘤生长增殖的癌蛋白,现在发现它可以引起肿瘤细胞自杀。自杀行为由癌蛋白促凋亡介导完成,MYC是其中的典型代表,癌蛋白的这种行为可能对肿瘤的发生发展具有重大意义,目前通过诱导肿瘤细胞凋亡治疗癌症是否完全合理,有待临床实践的进一步验证,今后的抗癌治疗应该辩证合理地看待肿瘤细胞凋亡。     

双语跨语言的句法启动

本文介绍了跨语言句法启动的图片描述法、补句法和句子回忆法三种研究方法;总结了跨语言句法启动研究关注的主要问题,包括：词序的一致性对跨语言句法启动的影响、词汇因素在跨语言句法启动中的作用、语言内和语言间句法启动的比较以及跨语言句法启动产生的机制等。同时也指出,在双语词序一致性,第二语言的熟练程度,双语语言学特性的差异性是否或者如何影响跨语言的句法启动等方面仍需进一步的研究     

Body image and body change strategies among adolescent males and females from Fiji, Tonga and Australia

The current study was designed to investigate the body image and body change strategies of adolescents from Fiji, Tonga and Australia. Participants were 628 Fijians, 463 Indo-Fijians, 598 Tongans and 535 European Australians. Adolescents completed measures of height, weight, body dissatisfaction, strategies to lose weight, increase weight and increase muscles. The results demonstrated that overweight adolescents were more dissatisfied with their bodies than those who were normal weight. Overweight Fijians and Tongans were more satisfied with their body than Indo-Fijian or Australian adolescents. Tongans, followed by Fijians and Indo-Fijians, were more likely to engage in strategies to lose weight, increase weight and increase muscles. These results are consistent with the focus in Fiji and Tonga on the value of the large body ideal, but may also reflect the recent focus on the attainment of a healthy body size.     

The Social Production of Altruism: Motivations for Caring Action in a Low-Income Urban Community

Contemporary social science paints a bleak picture of inner-city relational life. Indeed, the relationships of low-income, urban-residing Americans are represented as rife with distress, violence and family disruption. At present, no body of social scientific work systematically examines the factors that promote loving or selfless interactions among low-income, inner-city American individuals, families and communities. In an effort to fill that gap, this ethnographic study examined the motivations for altruism among a sample of adults (n = 40) who reside in an economically distressed housing community (i.e., housing project) in New York City. Content analyses of interviews indicated that participants attributed altruism to an interplay between 14 motives that were then ordered into four overarching categories of motives: (1) needs-centered motives, (2) norm-based motives deriving from religious/spiritual ideology, relationships and personal factors, (3) abstract motives (e.g., humanism), and (4) sociopolitical factors. The implications of these findings are discussed.     

语言产生中词频效应老化的神经基础与时间进程

词频效应指语言产生中人们对高频词汇的加工比低频词汇更快更准确的一种现象,它可能发生在语言产生中的不同阶段。对青年人和老年人词频效应的不同特点和加工机制进行比较,可以考察语言产生的认知老化机制。通过语言产生理论可对词频效应的老化进行预测,提出词频效应在个体发展和老化阶段的相对稳定性,分析老化导致词频效应相关的神经基础和加工时间进程的改变。未来研究可进一步分离词频效应与习得年龄效应对语言产生老化的影响,并扩展至神经退行性疾病患者中。     

入学过渡期高中新生大五人格与主观社会地位变化轨迹的关系：基于潜变量增长模型的分析

为了考察入学过渡期高中新生主观社会地位（subjective social status, SSS）的变化轨迹及人格在其中的作用,本研究对546名高一新生进行了历时4个月的4次追踪测试。基于潜变量增长模型的分析结果显示：（1）SSS呈阶段化线性增长,且个体间差异显著;（2）人格中的外倾性、宜人性、责任心和开放性均能显著预测SSS的初始水平;（3）外倾性、宜人性和神经质对SSS的第一阶段变化速度有显著预测作用。结果表明,SSS会在新生入学后1个月内初步形成,且人格与其变化轨迹有关。     

Cognitive plasticity in successful ageing: contributions from a learning potential assessment / Plasticidad cognitiva en el envejecimiento exitoso: aportes desde la evaluación del potencial de aprendizaje

Abstract

Despite numerous studies on the subject of successful ageing, few studies address the issue from a learning potential (LP) perspective. In Latin America there is no empirical background describing LP in successful ageing. In this study, 157 elderly Argentines were categorized into ageing trajectories (successful, normal and pathological ageing) based on objective scores from autonomy level, cognitive performance and mood state scales. Subjects were assessed with classic neuropychological tests, a cognitive reserve scale and an LP test. The results show differences in LP and cognitive reserve according to different ageing trajectories. This study establishes a regional precedent of relevance in the study of LP in elderly people pursuing successful ageing. It also provides evidence of the usefulness of incorporating instances of delayed free recall and recognition in an episodic memory and LP test.     

Effect of achievement motivation on cognitive control adaptations

Previous research addressing motivational effects on cognitive control adaptations primarily manipulated external rewards. In the present study, we examined whether achievement motivation, reflecting intrinsic motivation, modulates cognitive control adaptations. In each of two experiments, students were divided into a high achievement motivation group (HAM; Experiment 1: N?=?36; Experiment 2: N?=?39) and a low achievement motivation group (LAM; Experiment 1: N?=?30; Experiment 2: N?=?39) on the basis of the Achievement Motivation Scale. Cognitive control adaptations were assessed by sequential congruency effects (SCEs) in Flanker tasks. Using a standard Flanker task in Experiment 1 and examining response times, the HAM but not LAM participants showed evidence of cognitive control adaptations. Because SCEs in a standard Flanker task may reflect lower-level, bottom-up processes rather than cognitive control adaptations, we used an adapted version of the Flanker task in Experiment 2 that controlled for the potential influence of such processes. Experiment 2 again revealed evidence of SCEs in the HAM but not LAM participants. These results suggest that cognitive control adaptions may be modulated by achievement motivation. Such potential modulation could be taken into account when evaluating results of previous and future fundamental and applied studies on cognitive control adaptations.     

中国自杀未遂的流行特征及影响因素研究

自杀是一个严重的社会问题和公共卫生问题。但目前尚未完全了解自杀的影响因素以及预防自杀的方法。流行病学研究表明自杀未遂是自杀的重要预测因素,了解自杀未遂的特征以及影响因素将有助于减少自杀行为的发生。本文对自杀未遂的流行特征以及影响因素进行了综述。