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171.
Campaigns against reckless driving often mention the risk of dying. Research on terror management theory indicates that death claims may backfire and foster reckless driving. Here, we studied such mortality salience effects in a motorcyclist sample. Two moderating variables, particularly interesting regarding the sample of motorcyclists, were considered: group riding (vs. riding alone) and driving‐related self‐esteem. Motorcyclists were exposed to a campaign, either highlighting mortality or not. Orthogonally, cyclists were primed with riding in a group (vs. riding alone). Driving‐related self‐esteem was assessed via a questionnaire. We predicted that reminders of riding in a group would buffer against ironic mortality effects. Supporting this hypothesis, mortality salience effects interacted with the group prime. The results indicate that death appeals are likely to backfire with cyclists riding alone rather than cyclists riding in a group, especially if motorcycling is relevant to the self.  相似文献   
172.
This study builds on previous help‐seeking research in the United States by examining the role of counseling stigma in Turkey. Undergraduate students in Turkey (N = 520) completed self‐report measures of attitudes and intentions to seek counseling and 3 forms of help‐seeking stigma. Results indicated that perceptions of public and social network stigma each uniquely contributed to the experience of self‐stigma, which, in turn, influenced attitudes toward seeking counseling and then help‐seeking intentions.  相似文献   
173.
How long does it take to form a durable representation in visual working memory? Several theorists have proposed that this consolidation process is very slow. Here, we measured the time course of consolidation. Observers performed a change-detection task for colored squares, and shortly after the presentation of the first array, pattern masks were presented at the locations of each of the colored squares to disrupt representations that had not yet been consolidated. Performance on the memory task was impaired when the delay between the colored squares and the masks was short, and this effect became larger when the number of colored squares was increased. The rate of consolidation was approximately 50 ms per item, which is considerably faster than previous proposals.  相似文献   
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175.
In this study we tested 4-, 9-, 12-, and 18-month-old C57BL/6 mice in the 250-msec delay eyeblink classical conditioning procedure to study age-related changes in a form of associative learning. The short life expectancy of mice, complete knowledge about the mouse genome, and the availability of transgenic and knock-out mouse models of age-related impairments make the mouse an excellent species for expanding knowledge on the neurobiologically and behaviorally well-characterized eyeblink classical conditioning paradigm. Based on previous research with delay eyeblink conditioning in rabbits and humans, we predicted that mice would be impaired on this cerebellar-dependent associative learning task in middle-age, at ~9 months. To fully examine age differences in behavior in mice, we used a battery of additional behavioral measures with which to compare young and older mice. These behaviors included the acoustic startle response, prepulse inhibition, rotorod, and the Morris water maze. Mice began to show impairment in cerebellar-dependent tasks such as rotorod and eyeblink conditioning at 9 to 12 months of age. Performance in hippocampally dependent tasks was not impaired in any group, including 18-month-old mice. These results in mice support results in other species, indicating that cerebellar-dependent tasks show age-related deficits earlier in adulthood than do hippocampally dependent tasks.  相似文献   
176.
Mammalian memory is commonly "explained" in terms of long-term potentiation (LTP) of excitatory synapses. However, depotentiation of inhibitory pathways (disinhibition) is also a known phenomenon in the brain. Artificial neural networks which are offered as partial models of the cerebrum traditionally encode memory by the potentiation of excitatory "synapses" in a manner which is thought of as analogous to LTP. Analysis shows that such models have seriously limited storage capacities. The models also depend on mechanisms which do not appear to be biologically plausible. This paper demonstrates that these difficulties are avoided by encoding memory by means of disinhibition rather than LTP. The resulting models are simple and plausible, though unconventional.  相似文献   
177.
Cancer genetics professionals face a new opportunity and challenge in adapting to the availability of cancer genetic testing panels, now available as a result of Next Generation Sequencing (NGS) technology. While cancer panels have been available for over a year, we believe that there is not yet enough data to create practice guidelines. Despite this, a year of experience allows us to provide our opinion on points to consider as cancer genetic counselors incorporate this testing technology into genetic counseling practice models. NGS technology offers the ability to potentially diagnose hereditary cancer syndromes more efficiently by testing many genes at once for a fraction of what it would cost to test each gene individually. However, there are limitations and additional risks to consider with these tests. Obtaining informed consent for concurrent testing of multiple genes requires that genetics professionals modify their discussions with patients regarding the potential cancer risks and the associated implications to medical management. We propose dividing the genes on each panel into categories that vary by degree of cancer risk (e.g. penetrance of the syndrome) and availability of management guidelines, with the aim to improve patient understanding of the range of information that can come from this testing. The increased risk for identifying variants of uncertain significance (VUS) when testing many genes at once must be discussed with patients. Pretest genetic counseling must also include the possibility to receive unexpected results as well as the potential to receive a result in the absence of related medical management guidelines. It is also important to consider whether a single gene test remains the best testing option for some patients. As panels expand, it is important that documentation reflects exactly which genes have been analyzed for each patient. While this technology holds the promise of more efficient diagnosis for many of our patients, it also comes with new challenges that we must recognize and address.  相似文献   
178.
Ignoring gender socialization while counseling transgender clients neglects a significant aspect of the transgender experience. To address this, the authors review the literature on gender role conflict (GRC) theory as it pertains to the transgender experience of biological males whose authentic self is female. They explore the main types of distress experienced by transgender individuals, detail the therapeutic process using a GRC theory perspective, specify how GRC applies to transgender individuals, and suggest ways to work with this population.  相似文献   
179.
A full understanding of the development of the brain’s functional network architecture requires not only an understanding of developmental changes in neural processing in individual brain regions but also an understanding of changes in inter-regional interactions. Resting state functional connectivity MRI (rs-fcMRI) is increasingly being used to study functional interactions between brain regions in both adults and children. We briefly review methods used to study functional interactions and networks with rs-fcMRI and how these methods have been used to define developmental changes in network functional connectivity. The developmental rs-fcMRI studies to date have found two general properties. First, regional interactions change from being predominately anatomically local in children to interactions spanning longer cortical distances in young adults. Second, this developmental change in functional connectivity occurs, in general, via mechanisms of segregation of local regions and integration of distant regions into disparate subnetworks.  相似文献   
180.
Science and Engineering Ethics - Academia-intelligence agency collaborations are on the rise for a variety of reasons. These can take many forms, one of which is in the classroom, using students to...  相似文献   
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