Birth Weight and Childhood Psychopathology in the ABCD Cohort: Association is Strongest for Attention Problems and is Moderated by Sex

Research on Child and Adolescent Psychopathology - Many studies have shown low birth weight is associated with psychopathology later in life, particularly attention-deficit/hyperactivity disorder...     

瓜蒌皮与前列地尔预处理对心肌缺血再灌注的影响

探讨瓜蒌皮和前列地尔预处理对心肌缺血再灌注的作用机制.通过建立SD大鼠心肌缺血再灌注的模型,采用Tunel法检测组织样本细胞凋亡和免疫组化法检测bax,bcl-2,caspase-3的蛋白表达情况进行研究.结果显示,瓜蒌皮和前列地尔半剂量联合组的凋亡细胞数、Bax和caspase-3的蛋白表达量较其他各实验组均明显降低,Bcl-2的表达量升高,且有统计学意义(P＜0.05);瓜蒌皮单用药组也表现为凋亡细胞数、Bax和caspase-3的表达量降低,Bcl-2的表达量升高,但程度不如两组联合用药组.实验可以证明细胞凋亡发生在心肌缺血/再灌注损伤中,瓜蒌皮可对心肌缺血/再灌注起保护作用,并且与前列地尔联合后更有利于对心肌细胞的保护作用.     

Key Accounts and Team Selling: A Review,Framework, and Research Agenda

As sales organizations increase their reliance on sales teams, they must learn how organizational and interpersonal relationships influence sales teams, how sales teams play a learning role for organizations, and what makes sales teams effective. Presenting a model of interrelationships among members of the selling firm and between the selling and buying firms, we identify five key team selling relationships between (1) members of the same team, (2) members of different teams within the firm, (3) the selling team and the buying center, (4) the selling team and other groups in the selling firm, and (5) the selling team and the firm’s strategy. This model leads to a conceptual framework highlighting relationship drivers, factors, and outcomes instrumental to team selling success. After presenting propositions for future research, theoretical and methodological suggestions are included to facilitate research in this area. We conclude with perspectives on the future of research and practice in key accounts and team selling.     

Variation in Social Facilitation of Eating Behavior in Puppies

Observations of the play behavior of same-sex, same-age dyads of preschool children were made during 10-minute play sessions. Each of the 48 children participated both with a familiar peer and with an unfamiliar peer. The hypothesis that both boys and girls would show more interaction with familiar peers than unfamiliar peers was supported for younger girls and older boys. Younger boys seemed little influenced by the familiarity of their play companion, while older girls showed more social interaction with unfamiliar peers. Results were compared with studies that used projective techniques, and it was suggested that the effects of peer familiarity may appear earlier in actual behavior than through these techniques.     

Action mechanisms for social cognition: behavioral and neural correlates of developing Theory of Mind

Many psychological theories posit foundational links between two fundamental constructs: (1) our ability to produce, perceive, and represent action; and (2) our ability to understand the meaning and motivation behind the action (i.e. Theory of Mind; ToM). This position is contentious, however, and long‐standing competing theories of social‐cognitive development debate roles for basic action‐processing in ToM. Developmental research is key to investigating these hypotheses, but whether individual differences in neural and behavioral measures of motor action relate to social‐cognitive development is unknown. We examined 3‐ to 5‐year‐old children's (N = 26) EEG mu‐desynchronization during production of object‐directed action, and explored associations between mu‐desynchronization and children's behavioral motor skills, behavioral action‐representation abilities, and behavioral ToM. For children with high (but not low) mu‐desynchronization, motor skill related to action‐representation abilities, and action‐representation mediated relations between motor skill and ToM. Results demonstrate novel foundational links between action‐processing and ToM, suggesting that basic motor action may be a key mechanism for social‐cognitive development, thus shedding light on the origins and emergence of higher social cognition.     

A Seat at the Table: Using Social Media as a Platform to Resolve Microaggressions Against Transgender Persons

Transgender, gender variant, and/or gender nonconforming persons are marginalized and pathologized in society and communities. The advent and widespread use of social media introduce an entirely new avenue of expression where cyber bullying and verbal assaults are common. Yet, social media also has the capacity to reach more people in more places, thus presenting a potentially powerful platform for advocacy. Grounded in digital critical participatory action research, the authors present a multimedia advocacy project that highlights advocacy strategies in which counselors can utilize social media to raise awareness, promote inclusion, and resolve microaggressions toward transgender persons.     

An fMRI investigation of a novel analogue to the Trail-Making Test

The Trail-Making Test (TMT) is a widely used neuropsychological measure that assesses visuomotor abilities and cognitive flexibility. For the TMT-A condition participants are required to locate and connect numbers (i.e. 1-2-3…) while in the TMT-B condition participants perform the set-shifting task of locating and connecting numbers and letters (i.e. 1-A-2-B…). The TMT-B condition has shown impairments in many clinical populations, particularly schizophrenia patients, but the neurobiological underpinning of the task can be difficult to discern given pragmatic obstacles in adapting the task for neuroimaging. In a behavioural testing experiment we demonstrated a close correspondence between performance on the standard TMT and a novel, computer programmed adaptation of the TMT (pcTMT). The pcTMT was designed for functional magnetic resonance imaging (fMRI) administration and neuroimaging data for this task were obtained in. A whole brain analysis revealed significantly greater activation during the pcTMT-B relative to the pcTMT-A in right inferior/middle frontal cortices, right precentral gyrus, left angular gyrus/left middle temporal gyrus. These results identify the regions that most likely underlie cognitive flexibility during the TMT and are candidate regions underlying the impairment of groups with poor set-shifting abilities.     

Maternal gatekeeping, coparenting quality, and fathering behavior in families with infants

The present study examined the role of maternal gatekeeping behavior in relation to fathers' relative involvement and competence in child care in 97 families with infant children. Parents' beliefs about fathers' roles were assessed prior to their infant's birth. Parents' perceptions of maternal gatekeeping behavior (encouragement and criticism) and coparenting relationship quality were assessed at 3.5 months postpartum. The authors assessed fathers' relative involvement and competence in child care using a combination of parent report and observational measures. Results suggest that even after accounting for parents' beliefs about the paternal role and the overall quality of the coparenting relationship, greater maternal encouragement was associated with higher parent-reported relative father involvement. Moreover, maternal encouragement mediated the association between coparenting quality and reported relative father involvement. With respect to fathers' observed behavior, fathers' beliefs and parents' perceptions of coparenting relationship quality were relevant only when mothers engaged in low levels of criticism and high levels of encouragement, respectively. These findings are consistent with the notion that mothers may shape father involvement through their roles as "gatekeepers."     

环境基因组计划(EGP)对预防医学发展的影响

1998年美国正式启动环境基因组计划,该计划旨在探讨环境－基因的交互作用,寻找对环境因素损伤的易感基因及环境反应基因的多态性在疾病病因和发病过程中的作用,因而该计划的实施将对预防医学的发展产生重要的影响。