Neurochemical knowledge in electroconvulsive therapy (ECT)

The paper is concerned with an attempt to generalize and categorize current hypotheses on the biochemical basis of ECT. The hypotheses are critically evaluated with respect to the relevance of their experimental fundamentals. Thus, certain hypotheses are valid only in a qualified sense. Particular interest is focussed on those conceptions which try to correlate ECT-induced changes in synaptic receptor sensitivities (up-/down-regulation) with super- resp. subsensitivity hypotheses of psychoses. In this connection, noradrenergic and opioid systems on the one hand, and the axis hypothalamus-hypophysis on the other hand seem to play a dominant role.     

Diagnostic value of myelography as an expanded clinical study method

The paper investigates 54 myelograms and their influence on diagnostic thinking efficacy, on patient management efficacy, and on ultimate outcome efficacy, using statistical methods. Conventional myelography contributes to diagnostic thinking efficacy having a LLR- value of approximately 0.9. With an accuracy value of 0.95 it can be regarded as a reliable method of diagnosis. It alters diagnostic thinking efficacy in no less than 83% (94%) of the cases and patients management efficacy in 89%. Thus, by definition, myelography may be said to affect the state of health of the myelographed patients in 94.4%.     

Principles of computer-assisted classification in psychiatry

The use of computer based diagnostic decision and artificial intelligence are discussed in relation to the problems of validity and reliability of psychiatric diagnoses. The authors suggest a definition of a computer aided classificator as an existent decision system for an automatically analysis of findings.     

A view of aggression in phobic states

This article attempts to apply a theory of aggression as motivation to overcome obstacles to the understanding of phobic states and their formation. The role of aggression in the genesis of phobic conditions is discussed, and the traditional analytic view of aggression as instinctual drive is contrasted with a motivational approach. The motivational view offers the advantage of a clearer understanding of the stimulus contexts, representational connections, and both real and imaginary object connections that are lacking in the more traditional understanding of aggression as a biological drive.     

Psychopathology of progressive paralysis. Remarks on some personal cases

Four of our own cases that presented a clinical picture of dementia are discussed. A study of the relative literature has failed to reveal any "swing" in the pattern of the clinical condition: Just as it did ninety years age, paralytic dementia accounts today for well over 60% of all cases, those clinical pictures erroneously regarded as "typical" "classic", accounting for a mere 10%-15% of cases. The need for routine lues serology is pointed out.     

Psychometric detection of depressive mood conditions

An investigation into the diagnostic value of psychometric methods for the diagnosis of depressive states involved five psychometric questionnaires, one concentration test procedure, and one problem-solving approach to register cognitive processes. The data obtained for 80 depressive patients of varied aetiology were compared with those of sample of 80 neurotics without depressive aberration. Even univariate comparisons revealed statistically significant differences between the two samples. Multivariate methods (factor analysis, discriminative analysis) yielded more differentiated information. The "Scale for depression depth measurements" was found to be of particular diagnostic relevance; it was standardized for the time being.     

Personality and social resources in immediate and continued stress resistance among women

In this study we investigated the immediate and continued impact on women of a major stressful event, the outcome of pregnancy, and the mitigating effect of self-esteem and intimacy with their spouse on their reactions. Few other studies have investigated initial reactions to crisis events. Ninety-nine Israeli women who experienced either normal delivery or pregnancy complications were interviewed at the time of the event and 3 months later. High self-esteem was found to limit feelings of depression at both times. Intimacy with spouse limited depression at the event, but not at follow-up. High self-esteem was seen as always being exploitable by women who possessed it, whereas the benefit of intimacy with spouse was seen as being dependent on situational demands and environmental constraints. Cross-cultural implications were presented.