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61.
Neurophysiological experiments with monkeys have demonstrated that working memory (WM) is associated with persistent neural
activity in multiple brain regions, such as the prefrontal cortex (PFC), the parietal cortex, and posterior unimodal association
areas. WM maintenance is believed to require the coordination of these brain regions, which do not function in isolation but,
rather, interact to maintain visual percepts that are no longer present in the environment. However, single-unit physiology
studies and traditional univariate analyses of functional brain imaging data cannot evaluate interactions between distant
brain regions, and so evidence of regional integration during WM maintenance is largely indirect. In this study, we utilized
a recently developed multivariate analysis method that allows us to explore functional connectivity between brain regions
during the distinct stages of a delayed face recognition task. To characterize the neural network mediating the on-line maintenance
of faces, the fusiform face area (FFA) was defined as a seed and was then used to generate whole-brain correlation maps. A
random effects analysis of the correlation data revealed a network of brain regions exhibiting significant correlations with
the FFA seed during the WM delay period. This maintenance network included the dorsolateral and ventrolateral PFC, the premotor
cortex, the intraparietal sulcus, the caudate nucleus, the thalamus, the hippocampus, and occipitotemporal regions. These
findings support the notion that the coordinated functional interaction between nodes of a widely distributed network underlies
the active maintenance of a perceptual representation. 相似文献
62.
Corcoran P Reilly M Salim A Brennan A Keeley HS Perry IJ 《Suicide & life-threatening behavior》2004,34(4):429-438
Using Irish suicide data for the period 1990-1998, the independent effects of month and day adjusting for age, gender, and calendar year effects and distinguishing between holiday and working Mondays were assessed. The male suicide rate was significantly higher on working Mondays (+31%) and Saturdays (+14%), and during April, June, and August (+17%), after adjustment for the other variables. In contrast, female suicide rates were higher only in August (+35%) and exhibited no day effect. Teenage men had a greater elevation of risk on Saturdays, Sundays, and both working and holiday Mondays than any other group. The study findings should be taken into account in the planning of specialized health care services and helplines for suicidal people. Furthermore, the findings provide support for Gabennesch's (1988) broken promise theory and the relationship between dysfunctions of the serotonergic system and suicidal behavior. 相似文献
63.
Although there is increasing support for the hypothesis that negative cognitive styles contribute vulnerability to depression, it remains unclear how best to conceptualize the heterogeneity in cognitive vulnerability to depression. Specifically, does this heterogeneity reflect quantitative or qualitative differences among individuals? The goal of this study was to address this question by examining whether the underlying structure of cognitive vulnerability to depression is best conceptualized as dimensional or categorical. Taxometric analyses provided consistent support for the dimensional nature of negative cognitive styles. It appears, therefore, that cognitive vulnerability to depression is best conceptualized as a dimensional construct, present to a greater or lesser extent in all individuals. Despite this, the strength of the relationship between negative cognitive styles and depressive symptoms does appear to vary as a function of where along the cognitive style continuum one falls. 相似文献
64.
Differential effects of emotional arousal in short- and long-term memory in healthy adults 总被引:4,自引:0,他引:4
Quevedo J Sant'Anna MK Madruga M Lovato I de-Paris F Kapczinski F Izquierdo I Cahill L 《Neurobiology of learning and memory》2003,79(2):132-135
Recent studies demonstrated important differences between short- and long-term memory mechanisms. Besides, the emotional component has a crucial role in memory formation. This study was carried out to answer whether there is a differential influence of emotional arousal in short- and long-term memory in healthy adults. Thirty-one healthy volunteers were divided into two major groups. In the first group long-term memory (LTM) was evaluated, with the testing session one week after training. The second group was tested 1h after training, where short-term memory (STM) was evaluated. Each group was divided in to two subgroups. One half of the volunteers was exposed to an emotionally neutral story, and the other half of each group was exposed to a closely matched but more emotionally arousing story. The testing session consisted of a questionary containing 80 questions of multiple choices. The results were evaluated through percentage of correct answers. Results showed that correct answers were increased, in LTM measures, in the subjects that were given the emotional version of the test. In STM measures, no differences were found between the emotional and neutral version. However, the presentation of emotional story caused an emotional reaction in both groups. The lack of effect of emotional arousal in STM suggests that amygdala is not related to STM mechanisms. Further studies using different approaches are needed to elucidate if STM processes are influenced by emotional arousal. 相似文献
65.
Anna?SzékelyEmail author Simonetta?D’Amico Antonella?Devescovi Kara?Federmeier Dan?Herron Gowri?Iyer Thomas?Jacobsen Elizabeth?Bates 《Behavior research methods》2003,35(4):621-633
Factors affecting word retrieval were compared in a timed picture-naming paradigm for 520 drawings of objects. In prior timed
and untimed studies by Snodgrass and Vanderwart (1980) and Snodgrass and Yuditsky (1996), concerns were raised that participants
could not reliably name large numbers of items in a single session. We show that reliable results are obtained in a single
session for 520 items and validate our method against previous findings by Snodgrass and colleagues for overlapping items.
For these items, comparable levels of name agreement and latency are obtained, and we replicate effects of length, frequency,
both objective and subjective age of acquisition, and visual complexity on reaction time (RT) and name agreement measures.
Name agreement is unaffected by order of presentation, although there is a gradual increase in RTs across the session, requiring
use of multiple random orders. Current extensions of our method include cross-linguistic, bilingual, developmental, and neuropsychological
studies and comparisons of action naming and object naming. 相似文献
66.
Ann R. Bradlow Reiko Akahane-Yamada David B. Pisoni Yoh’ichi Tohkura 《Attention, perception & psychophysics》1999,61(5):977-985
Previous work from our laboratories has shown that monolingual Japanese adults who were given intensive high-variability perceptual training improved in both perception and production of English /r/-/l/ minimal pairs. In this study, we extended those findings by investigating the long-term retention of learning in both perception and production of this difficult non-native contrast. Results showed that 3 months after completion of the perceptual training procedure, the Japanese trainees maintained their improved levels of performance on the perceptual identification task. Furthermore, perceptual evaluations by native American English listeners of the Japanese trainees’ pretest, posttest, and 3-month follow-up speech productions showed that the trainees retained their long-term improvements in the general quality, identifiability, and overall intelligibility of their English /r/-/l/ word productions. Taken together, the results provide further support for the efficacy of high-variability laboratory speech sound training procedures, and suggest an optimistic outlook for the application of such procedures for a wide range of “special populations.” nt]mis|This work was supported by NIDCD Training Grant DC-00012 and by NIDCD Research Grant DC-00111 to Indiana University. 相似文献
67.
Memory for previously learned figural sequences and item-to-item covariations within figural sequences was examined under explicit and implicit instructional conditions in three age groups: young adults (17-23 years); middle-aged adults (35-45 years); and older adults (55-65 years). In Phase 1 of the experiment, the acquisition phase, half the subjects in each age group learned sequences of three to eight items in which the item-to-item changes conformed to an artificial grammar, and the other half of the subjects in each age group learned strings in which the item-to-item changes were nongrammatical. In Phase 2, the implicit/explicit test phase, subjects made forced-choice judgments about parts of the strings that they learned in Phase 1, under either explicit or implicit instructions. Analyses of Phase 2 data revealed that subjects in both instructional conditions used item-to-item covariations in making decisions about grammatical strings. However, use of previously learned covariations as well as the number of correct judgments about previously learned strings was greater in the explicit condition than in the implicit condition. An age-related deficit was found for explicit recognition of grammar-following sequences. 相似文献
68.
Despite menstruation being a physiological phenomenon in women’s life, social research has highlighted that there are still many taboos, also conveyed by advertising, which prevent an open discourse on the topic and can have negative impacts on women’s well-being. The present study examined the influence of the exposure to existing TV advertisements for sanitary napkins depicting menstruation as a taboo on self-objectification in women from Italy (n = 160) and Sweden (n = 159). To do so, we also investigated the moderating role of menstrual knowledge in this relationship. Our findings showed that in the Italian sample, exposure to the taboo TV commercial led to more self-objectification especially for participants with lower knowledge of menstruation. These effects did not occur for their Swedish counterparts, showing no differences in self-objectification when women were exposed to the taboo advertisement. The present results are discussed in light of cultural differences in sexual and menstrual education between the two countries. Theoretical and practical implications are drawn. 相似文献
69.
Counselor Education Students’ Perceptions of Wellness and Mental Health in African American Men: The Effects of Colorism
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Tiffany R. Hairston John M. Laux Caroline O’Hara Christopher P. Roseman Shanda Gore 《Journal of multicultural counseling and development》2018,46(3):171-185
Colorism is discrimination based on skin tone. Skin color influences clinicians’ diagnostic impressions. The degree to which colorism influences counseling students’ clinical decision making is unknown. This study examined colorism's effect on counselor education master's students’ (N = 154) clinical decisions. Analysis of covariance failed to produce statistically significant results when comparing students’ evaluations of a male African American's mental health and wellness, when controlling for presentation management, across 4 skin tones. Counselors should include colorism in diversity training. El colorismo es la discriminación basada en el tono de la piel. El tono de la piel influye en las impresiones diagnósticas de los profesionales clínicos. Se desconoce hasta qué punto el colorismo influye en las decisiones clínicas de los estudiantes de consejería. Este estudio examinó el efecto del colorismo en las decisiones clínicas de estudiantes de maestría en educación de consejeros (N = 154). El análisis de la covarianza no produjo resultados estadísticamente significativos al comparar las evaluaciones de los estudiantes sobre la salud mental y el bienestar de un cliente afroamericano varón, controlando la gestión de la presentación de 4 tonos de piel diferentes. Los consejeros deberían incluir el colorismo en la capacitación de diversidad. 相似文献
70.
Jessica L. Waxler Kelsey E. O’Brien Linda M. Delahanty James B. Meigs Jose C. Florez Elyse R. Park Barbara R. Pober Richard W. Grant 《Journal of genetic counseling》2012,21(5):684-691
Advances in genetic epidemiology have increased understanding of common, polygenic preventable diseases such as type 2 diabetes. As genetic risk testing based on this knowledge moves into clinical practice, we propose that genetic counselors will need to expand their roles and adapt traditional counseling techniques for this new patient set. In this paper, we present a genetic counseling intervention developed for a clinical trial [Genetic Counseling/Lifestyle Change for Diabetes Prevention, ClinicalTrials.gov identifier: NCT01034319] designed to motivate behavioral changes for diabetes prevention. Seventy-two phenotypically high-risk participants received counseling that included their diabetes genetic risk score, general education about diabetes risk factors, and encouragement to participate in a diabetes prevention program. Using two validated genetic counseling scales, participants reported favorable perceived control and satisfaction with the counseling session. Our intervention represents one model for applying traditional genetic counseling principles to risk testing for polygenetic, preventable diseases, such as type 2 diabetes. 相似文献