Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear

Recent studies using lesion, infusion, and unit-recording techniques suggest that the infralimbic (IL) subregion of medial prefrontal cortex (mPFC) is necessary for the inhibition of conditioned fear following extinction. Brief microstimulation of IL paired with conditioned tones, designed to mimic neuronal tone responses, reduces the expression of conditioned fear to the tone. In the present study we used microstimulation to investigate the role of additional mPFC subregions: the prelimbic (PL), dorsal anterior cingulate (ACd), and medial precentral (PrCm) cortices in the expression and extinction of conditioned fear. These are tone-responsive areas that have been implicated in both acquisition and extinction of conditioned fear. In contrast to IL, microstimulation of PL increased the expression of conditioned fear and prevented extinction. Microstimulation of ACd and PrCm had no effect. Under low-footshock conditions (to avoid ceiling levels of freezing), microstimulation of PL and IL had opposite effects, respectively increasing and decreasing freezing to the conditioned tone. We suggest that PL excites amygdala output and IL inhibits amygdala output, providing a mechanism for bidirectional modulation of fear expression.     

Contextual basis of maternal perceptions of infant temperament

To elucidate the differential saliency of infant emotions to mothers across interactive contexts, the authors examined the moderating role of observed infant affect during interactions with mother in the relation between maternal and laboratory-based ratings of infant temperament. Fifty-nine developmentally healthy 9-month-old infants were judged for degree of infant positive, infant negative, and mother-infant mutually positive affect during the course of object-focused and routine home-based activities with mother. Mothers completed the Infant Behavior Questionnaire (M. K. Rothbart, 1981), and infants underwent the Laboratory Temperament Assessment Battery (H. H. Goldsmith & M. K. Rothbart, 1999). Results revealed that maternal and observer ratings of infant negativity converged when infants manifested high degrees of negative affect during routine home-based activities. Maternal and observer ratings of infant positivity converged when infants experienced low mutually positive affect during play. These findings support the hypothesis that maternal perceptions are based on mothers' experiences with their infants but that the salience of infant temperamental characteristics to mothers varies across emotion and interactive context.     

Between ignorance and truth: Partition dependence and learning in judgment under uncertainty

In 3 studies, participants viewed sequences of multiattribute objects (e.g., colored shapes) appearing with varying frequencies and judged the likelihood of the attributes of those objects. Judged probabilities reflected a compromise between (a) the frequency with which each attribute appeared and (b) the ignorance prior probability cued by the number of distinct values that the focal attribute could take on. Thus, judged probabilities were partition dependent, varying with the number of events into which the state space was subjectively divided. This bias was diminished among participants more confident in what they learned, was strong and insensitive to level of confidence when ignorance priors were especially salient, and required ignorance priors to be salient only when probabilities were elicited (not during encoding).     

Psychiatric hospitalization after deliberate self-poisoning

The decision for psychiatric hospitalization after deliberate self-poisoning (DSP) is not well understood. This study, a longitudinal cohort study of 3,148 consecutive DSP patients found 920 (29.2%) subjects were referred for psychiatric hospitalization, 576 (18.3%) on involuntary basis. A logistic regression analysis showed increased risk for: age 25 or older, homelessness, unemployment, previous self-harm, psychiatric inpatient treatment within 12 months, earlier psychiatric inpatient treatment, suicidal ideation or plan, mood or psychotic disorders, and lower clinician experience; and lower risk for being married/defacto, and after hours presentation. Recommendation for psychiatric hospitalization was based on complex decision making. These findings have implications for clinical practice guidelines, service costs, and service organization.     

Ordinary variations in maternal caregiving influence human infants' stress reactivity

ABSTRACT— We sought to extend earlier work by examining whether there are ordinary variations in human maternal caregiving behavior (MCB) that are related to stress reactivity in infants. We observed 185 mother-infant dyads and used standard coding systems to identify variations in caregiving behavior. We then created two extreme groups and found that infants receiving low-quality MCB showed more fearfulness, less positive joint attention, and greater right frontal electroencephalographic asymmetry than infants receiving high-quality MCB. Group differences in stress reactivity were not a result of measured infant temperament. However, infants receiving low-quality MCB manifested significantly more negative affect during caregiving activities than did infants receiving high-quality MCB. The results suggest that ordinary variations in MCB may influence the expression of neural systems involved in stress reactivity in human infants.     

Learning disabilities and performance on the Pennsylvania System of School Assessment

The No Child Left Behind Act mandates all students in schools receiving Title I funds show proficiency in reading by 2014. This stricture applies to students with diagnosed learning disabilities as well as to students without learning disabilities. Multiple regression analyses on data for seniors attending a Grade 9-12 predominately white, comprehensive vocational-technical school indicated that, when absenteeism, socioeconomic status, and sex were held constant, the 26 students with diagnosed learning disabilities scored 246.7 points lower on the Pennsylvania System of School Assessment Reading subtest (n = 107) and 214.4 points lower on the Pennsylvania System of School Assessment Mathematics subtest (n = 106) than students not so diagnosed, and the 27 students diagnosed with learning disabilities scored 126.3 points lower on the Writing subtest (n= 114) than students not so diagnosed.     

Building Bridges Across Differences to Meet Social Action Goals: Being and Creating Allies Among People of Color

Although challenges of anti-racist work are most commonly framed in relation to White people and People of Color, there are significant challenges involved in creating allies across minority racial groups. This article describes our experiences within a community organization aimed at training anti-racist culturally sensitive K-12 educators. As Asian American and Native American facilitators within a group of facilitators of color who were predominantly Black, we describe our experiences of relative marginalization and our (mostly failed) attempts to create change within the organization to be more inclusive of the perspectives, experiences, and needs of non-Black people/students of color. We contextualize these experienced conflicts in relation to race hierarchies, the “divide and conquer strategy” and the maintenance of White privilege. We offer reflections for how racial minorities engaged in anti-racist education could be better allies and how organizations might better foster environments that contribute to the creation of these alliances.

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Deconstructing therapy outcome measurement with Rasch analysis of a measure of general clinical distress: the Symptom Checklist-90-Revised

Rasch analysis was used to illustrate the usefulness of item-level analyses for evaluating a common therapy outcome measure of general clinical distress, the Symptom Checklist-90-Revised (SCL-90-R; Derogatis, 1994). Using complementary therapy research samples, the instrument's 5-point rating scale was found to exceed clients' ability to make reliable discriminations and could be improved by collapsing it into a 3-point version (combining scale points 1 with 2 and 3 with 4). This revision, in addition to removing 3 misfitting items, increased person separation from 4.90 to 5.07 and item separation from 7.76 to 8.52 (resulting in alphas of .96 and .99, respectively). Some SCL-90-R subscales had low internal consistency reliabilities; SCL-90-R items can be used to define one factor of general clinical distress that is generally stable across both samples, with two small residual factors.     

Effect of bandwidth knowledge of results on the learning of a grip force control task

An experiment was conducted to investigate the persistence of the effect of "bandwidth knowledge of results (KR)" manipulated during the learning phase of performing a manual force-control task. The experiment consisted of two phases, an acquisition phase with the goal of maintaining 60% maximum force in 30 trials, and a second phase with the objective of maintaining 40% of maximum force in 20 further trials. There were four bandwidths of KR: when performance error exceeded 5, 10, or 15% of the target, and a control group (0% bandwidth). Analysis showed that 5, 10, and 15% bandwidth led to better performance than 0% bandwidth KR at the beginning of the second phase and persisted during the extended trials.     

Separation of Religion and State and Secularism in Theory and in Practice

Abstract

This study examines whether states follow the religion policies they declare in their constitutions. It identifies four types of policies which officially seek to limit religion's role in government: absolute separation of religion and state (SRAS); neutral political concern; exclusion of ideals; and secularism–laicism. I determine whether states follow these policies using the religion and state (RAS) dataset and compare this to constitutional declarations that the state is secular and declarations of separation of religion and state. The results show that a majority of states which make both types of declaration do not follow these policies based on any of the four standards used in this study. However, the presence and wording of these clauses are correlated with state religion policy.