Comparative clinicogenetic study of schizophrenic psychoses

The author diagnoses 350 carefully selected schizophrenic subjects, their parents and their siblings during parallel studies using three different clinical classification systems and analyzes the results by multiple threshold analysis and the multifactorial inheritance model. The results suggest that, of the three classifications the author studied, Leonhard's and Sneshnewski's system yield relatively homogeneous subgroups; this indicates the future significance of these nosological systems for the planning of biopsychiatric research.     

Stress as a state of anticipatory vigilance

The pituitary-adrenocortical system is activated in stressful situations, and the adrenocortical hormones have been implicated by Selye in the diseases of stress. Evidence indicates that the adrenocortical hormones peak during the period of anticipation of stressful events, not during actual confrontation with them. The circadian cortisol rhythm shows peaks before waking, not during active periods of the day, and cortisol does not appear to be required during physical activity. The role of these hormones appears to be to suppress ongoing physiological activity in order to increase vigilance and to get the organism ready to take action before the impact of dangers.     

Lay conceptions of personality: Eliciting tiers of a scientific conception of personality

Two studies are reported which examine the availability of scientific propositions of personality in lay conceptions of personality. It is argued from a social constructivist perspective that models of personality must derive from and refer to lay conceptions of persons. Eysenck's trait-type model of introversion-extraversion, containing specific propositions about phenotypic and genotypic differences between extraverts and introverts, was utilized as the scientific model of personality and its availability in lay conceptions of personality was examined in two studies. In the first study, subjects were presented with a genotypic characterization of either an introvert or an extravert target person and asked to infer corresponding phenotypic differences. In the second study, the inference process was reversed with subjects being asked to infer genotypic characteristics of introverts versus extraverts on the basis of phenotypic target person desecrations of the two types. Results from both studies show a high degree of accuracy in subjects' inferences, suggesting that laypersons have well-formed conceptions about personality containing ‘higher-order’ psychogenetic propositions corresponding to Eysenck's trait-type model. The implications of the findings for theory construction are discussed.     

The word frequency effect in lexical decision: Finding a frequency-based component

Subjects making lexical decisions are reliably faster in responding to high-frequency words than to low-frequency words. This is known as the word frequency effect. We wished to demonstrate that some portion of this effect was due to frequency differences between words rather than to other dimensions correlated with word frequency. Three groups of subjects (10 engineers, 10 nurses, and I0 law students) made lexical decisions about 720 items, half words and half nonwords, from six different categories (engineering, medical, low-frequency nontechnical, medium-frequency nontechnical, and two groups of high-frequency nontechnical). Results of two analyses of variance revealed a crossover interaction such that engineers were faster in responding to engineering words than to medical words, whereas nurses were faster in responding to medical words than to engineering words. The engineering and medical words were equally long and equally infrequent by standard word counts. We take this as support for a frequency-based component in the word frequency effect. The practical implications of this research for estimating the readability of technical text are discussed.     

Social structure features in three inbred strains of mice, C57Bl/6J, Balb/cj, and NIH: a comparative study

Some features of social living were investigated in three inbred strains of mice: C57Bl/6j, Balb/cj, and NIH. Five social behaviors--Aggression, Submission, Allogrooming, Social Rest and Rest Alone, as well as Wheel Running Activity--were recorded 2 h daily for a week, in 26 groups of seven male mice living in an enriched environment. Dominants and subordinates among strains shared some behavioral characteristics, but strain contributions upon social structure were also detected. Similarities among strains included the appearance of a single dominant mouse per group rated as the most aggressive, besides from being the animal presented with most Submissions. Allogrooming was more frequent among subordinates than among dominants and subordinates. Differences among strains were that agonistic behavior among subordinates was higher in the Balb/cj and NIH groups than in the C57Bl/6j mice. NIH mice were recorded in Rest Alone more often than mice from the other strains. C57Bl/6j dominants showed higher rates of Wheel Running Activity than subordinates.     

Affect, personality, and facial expressive characteristics of older people

This study explored the relationship between emotion-based personality traits and expressive patterns in older subjects. Specifically, the study sought to demonstrate (a) that individuals have emotion expression biases, as revealed by structural and dynamic properties of the face, and (b) that there is a link between facial characteristics (as indexed by the judgments of trained and naive raters) and personality traits. An encoding/decoding paradigm was used; 30 adult, naive judges rated five emotion-pose photographs for each of 14 older subjects who had also completed a personality trait measure. Results indicated that individuals vary in their ability to accurately encode emotion states and that these patterns are linked to personality traits in an affect-specific way. The results are discussed within the framework of Darwinian theory and Plutchik's model of personality.     

On structural equation modeling with data that are not missing completely at random

A general latent variable model is given which includes the specification of a missing data mechanism. This framework allows for an elucidating discussion of existing general multivariate theory bearing on maximum likelihood estimation with missing data. Here, missing completely at random is not a prerequisite for unbiased estimation in large samples, as when using the traditional listwise or pairwise present data approaches. The theory is connected with old and new results in the area of selection and factorial invariance. It is pointed out that in many applications, maximum likelihood estimation with missing data may be carried out by existing structural equation modeling software, such as LISREL and LISCOMP. Several sets of artifical data are generated within the general model framework. The proposed estimator is compared to the two traditional ones and found superior.The research of the first author was supported by grant No. SES-8312583 from the National Science Foundation and by a Spencer Foundation grant. We wish to thank Chuen-Rong Chan for drawing the path diagram.     

A CROSS-CULTURAL STUDY OF PSYCHOLOGICAL DIFFERENTIATION

A cross-cultural study of psychological differentiation of Canadian and Pakistani high school students was undertaken to examine the nature of psychological differentiation in relation to differences in age/grade, gender, and academic programs. The study involved 707 Canadian students from grades 6, 8, 10, and 12; and 349 Pakistani students from grades 8, 9, 10, and 12. The Group Embedded Figures Test was employed as a measure of the field-dependence-independence cognitive style. Analyses of data included two-way and three-way analyses of variance to determine the effects of grade, gender, and academic program upon GEFT scores. Differences in psychological differentiation between high school students in the two cultures were discussed in terms of Berry's eco-cultural model.     

Some problems of genetic counseling in schizophrenic psychoses

The authors sum up the most important basic principles of diagnostics and genetics of the schizophrenic psychoses from the viewpoint of genetic counseling for the practising psychiatrist and medical geneticist. Regarding genetic counselling strategy, in addition to nosological considerations, they stress the importance of socio-cultural and social psychological factors and of the emotional atmosphere in the family, which should all be taken into account together. Because of the special situation of schizophrenic (and in general, psychiatric) patients and their families, they regard it as advisable to set up a separate psychiatric genetic counselling service.