Stress modulation of cognitive and affective processes

This review summarizes the major discussion points of a symposium on stress modulation of cognitive and affective processes, which was held during the 2010 workshop on the neurobiology of stress (Boulder, CO, USA). The four discussants addressed a number of specific cognitive and affective factors that are modulated by exposure to acute or repeated stress. Dr David Morilak discussed the effects of various repeated stress situations on cognitive flexibility, as assessed with a rodent model of attentional set-shifting task, and how performance on slightly different aspects of this test is modulated by different prefrontal regions through monoaminergic neurotransmission. Dr Serge Campeau summarized the findings of several studies exploring a number of factors and brain regions that regulate habituation of various autonomic and neuroendocrine responses to repeated audiogenic stress exposures. Dr Kerry Ressler discussed a body of work exploring the modulation and extinction of fear memories in rodents and humans, especially focusing on the role of key neurotransmitter systems including excitatory amino acids and brain-derived neurotrophic factor. Dr Israel Liberzon presented recent results on human decision-making processes in response to exogenous glucocorticoid hormone administration. Overall, these discussions are casting a wider framework on the cognitive/affective processes that are distinctly regulated by the experience of stress and some of the brain regions and neurotransmitter systems associated with these effects.     

Brain-imaging studies of posttraumatic stress disorder

Brain-imaging studies of posttraumatic stress disorder (PTSD) have rapidly increased in recent years. Structural studies have identified potential smaller volumes of the hippocampus of traumatized and/or PTSD subjects. Functional activation studies have implicated hyperactive or altered functioning of brain regions, such as the amygdala and the insula, and a failure to engage emotional regulatory structures, such as the medial prefrontal and anterior cingulate cortex. Recent neurochemical investigations have suggested that neuromodulatory systems (eg, gamma-aminobutyric acid, micro-opioid) may underlie these aberrant brain activation patterns. This article reviews the literature on structural, functional, and neurochemical brain-imaging studies of PTSD.     

Sex-role imitation in children: Effects of sex of child,sex of model,and sex-role appropriateness of modeled behavior

The qualifying influence of the sex-role appropriateness of observed behavior on children's same-sex imitation was investigated. In each of two studies employing a 2×2×2 design, girls and boys observed a live male or female model display appropriate (to the child's sex) or inappropriate behavior. Results that were consistent in both studies indicated an interaction between sex of child and appropriateness. Boys imitated less when exposed to the inappropriate than to the appropriate sequence. An interaction between sex of child and sex of observer was obtained on only one measure in Experiment I (girls responded more quickly to a female than to a male model). In this study, girls also displayed greater opposite-sex imitation than boys; in Experiment II, there were no differences between boys and girls in either same- or opposite-sex imitation. The results are discussed with regard to the same-sex hypothesis and the differential impact of sex-role factors on boys and girls.The authors wish to thank the children, parents, and staff of Forest Park Elementary School for their participation and cooperation in the conduct of this study. Special thanks are extended to Mr. Paul H. Daby, Principal. The contribution of the undergraduate models and experimenters is also acknowledged.     

A Plea For Plurealism

In contrast to monistic realism (as represented by Peirce) and pluralistic irrealism (as represented by Goodman) I argue for what I call plurealism, a view which is both pluralistic and realist, recognizing different worlds that are not only independent of one another, but also independent of us.     

Effect of inversion on the recognition of external and internal facial features

The purpose of the present study was to find out whether inversion affects recognition of external and internal facial features. 24 participants matched, under two experimental conditions (pair and multiple-choice matchings), upright target faces with three categories of facial test stimuli: full faces, external features and internal features, which were presented in either upright or inverted orientations. Data analysis showed that matching of facial stimuli was faster, more accurate and more consistent under upright than under inverted orientations for all stimulus categories; mostly for full faces, and least for internal features. As a rule, there were no speed-accuracy trade-offs. Implications of the data for accounts of the inversion effect in face recognition in terms of a shift from configurational to componential processing were discussed.     

Use of a structured investigative protocol enhances young children's responses to free-recall prompts in the course of forensic interviews

One hundred alleged victims of child sexual abuse (ages 4-12 years; M = 8.1 years) were interviewed by police investigators about their alleged experiences. Half of the children were interviewed using the National Institute of Child Health and Human Development's structured interview protocol, whereas the other children--matched with respect to their age, relationship with the alleged perpetrator, and seriousness of the alleged offenses--were interviewed using standard interview practices. Protocol-guided interviews elicited more information using open-ended prompts and less information using option-posing and suggestive questions than did standard interviews; there were no age differences in the amount of information provided in response to open-ended invitations. In 89% of the protocol interviews, children made their preliminary allegations in response to open-ended prompts, compared with 36% in the standard interviews.     

Styles of problem solving in suicidal individuals

This study compared qualitative aspects of problem solving among suicide attempters, suicide ideators, and nonsuicidal patients. The subjects completed a suicidal intent scale and a problem-solving task involving three dilemmas. Problem solving was analyzed along eight qualitative categories: versatility of the various solutions, reliance on self versus others, activity versus passivity, confrontation versus avoidance, relevance of the solution to the problem, positive versus negative affect, reference to the future, and extremity of the solution. The statistical analysis yielded differences among the three groups. In general, the solutions of suicidal patients showed less versatility, more avoidance, less relevance, more negative affect, and less reference to the future than the solutions of the nonsuicidal patients. The suicide attempters and nonsuicidal patients offered more active solutions than did the suicide ideators. Our findings emphasize the importance of general coping styles, as well as energetic/motivational aspects and affective aspects of the problem-solving process. Some applications to therapy are discussed.