The vasopressin (VP)/oxytocin (OT)-related peptides constitute a large superfamily found in a wide range of both vertebrate and invertebrate species. While intensive literature reports that these neuropeptides influence behavior, especially learning and memory, in numerous species from diverse vertebrate groups, their roles in behavioral regulation have never been studied in invertebrates. Here, we investigated the role of two VP/OT superfamily peptides, octopressin (OP) and cephalotocin (CT), on long-term memory (LTM) formation of a passive avoidance task in a cephalopod mollusc, the cuttlefish, Sepia officinalis. Subadult cuttlefish were intravenously injected, in a dose range of 3–60 μg/kg, 1 h after the training phase (consolidation design); retention performance was tested 24 h post-training. We found that administration of OP at low dose (3 μg/kg) enhanced LTM, whereas a dose of 60 μg/kg attenuated it. No effect of OP on LTM was observed for the 15 μg/kg dose. Conversely, an enhancement of retention performance was observed at all doses of CT tested. This study is the first to demonstrate the behavioral effects of VP/OT superfamily peptides in an invertebrate species. The valuable role of VP/OT-like peptides on memory processes offers new evolutionary perspectives on peptidergic transmission and neuromodulation. 相似文献
ObjectiveThis study explored the paths between dimensions of self-efficacy and job search strategies. An examination of social cognitive career theory and career adaptability enabled us to consider several paths between dimensions of self-efficacy and job search strategies, as well as among self-efficacy dimensions.MethodScales measuring these concepts were administered to a sample of 120 jobseekers.ResultsStructural analyses allowed us to confirm expected paths. Barrier coping efficacy is significantly related to career decision self-efficacy. Career decision self-efficacy and job search self-efficacy are related to exploratory strategy and to job search strategy.ConclusionResults are discussed with reference to the literature and in terms of practical implications. They highlight the need to implement interventions in order to increase barrier coping efficacy and career decision self-efficacy. 相似文献
This paper suggests that one single thread characterizes the developments of French phenomenology that occurred after 1990 in the wake of Merleau-Ponty's and Levinas's major contributions. Janicaud in 1991 had already identified one global trend in French phenomenology and believed it was possible to unite the thoughts of Levinas, Henry, Marion and Chrétien under the common banner of “theological phenomenology.” However, his analysis seems to fail to account for deeper-seated affinities that exist between French phenomenologists such as Marion, Lacoste, Chrétien, Richir, Depraz, Romano – and Benoist for part of his work. This is the reason why, although the present paper does agree with Janicaud's idea that the French authors who define themselves as phenomenologists share some common ground, it defines this common trend quite differently, i.e., as a form of epistemological realism that ultimately manifests itself as a radical empiricism.
Consequently, the present study will state and defend three hypotheses: (1) contemporary French phenomenology professes a form of realism of experience, which is the true rallying point (space of exchange) of otherwise differing elaborations; (2) this type of epistemological empiricism, by virtue of its radicality, implies a problem that threatens to drive phenomenology towards its own dissolution, because as it precipitates in fine the dilution of philosophical discourse into a multitude of other discourses; (3) this variant of empiricism shows that, within its strictly defined viewpoint, there is scarcely any difference between French phenomenology and a certain part of French analytical philosophy. All three hypotheses lead to the same conclusion: the determination of the defining aspect of contemporary French phenomenology entails, beyond the apparent, misleading, and futile quarrel of paradigms, to bring to light a common space for contemporary French philosophy, which, from both perspectives, can be conveyed by the single term “to show.” It is, in fact, the elevation of “to show” to the detriment of “to demonstrate” that seems to ensnare thinkers within an impasse. 相似文献
Modelling ecologists have entered ecology labs. They need large quantities of data to improve their models and are eager to collaborate with field naturalists. This modifies existing relationships between these two groups of natural scientists who have different ways of knowing. We observed how a new border zone was being opened up between modelling ecologists and field naturalists working in a National Botanical Conservatory in France. After an arduous start, due to the initial reluctance of the field naturalists, the modelling ecologists and the field naturalists performed several activities together: they transformed existing data, produced new data, interpreted all these data, articulated research questions and hypotheses. They also created a hybrid database, mixing data from different sources, and they co-authored papers. This clearly changed the professional status of the field naturalists, who felt they were finally treated as genuine research partners. Yet, the modelling ecologists and the field naturalists remained as two distinct groups, with their specific practices, aims, skills and identities. Although collaboration was considered a clear success from both sides, there were some lingering tensions. The field naturalists were still somewhat wary of being downgraded to the status of mere data providers. They were therefore determined to see to it that their work and way of knowing would receive due recognition in the long run. 相似文献
Monoamine oxidase A (MAO A) degrades serotonin, dopamine and noradrenaline, factors critically involved in the regulation of aggression. Different kinds of aggression were investigated in Tg8, a transgenic mouse strain lacking a functional MAO A gene. MAO A-deficient mice differ from wild-type C3H/HeJ (C3H) in terms of showing higher territorial, predatory and isolation-induced aggression. Tg8 demonstrated shorter latencies to cricket killing and to the first attack after 6 weeks isolation than C3H mice. In the resident-intruder paradigm, MAO A-lacking mice were more aggressive than C3H when tested as intruders. In contrast to C3H, attack in Tg8 mice did not depend on different aggressiveness of intruders of BALB/c, A/Sn and C3H strains. Tg8 mice displayed no increase in aggression but demonstrated reduced social investigation towards anesthetized, as well as towards juvenile BALB/c males. Thus, MAO A deficiency in Tg8 mice is accompanied by increased expression of different kinds of aggression, as well as by disruption of normal pattern of social interaction. 相似文献
We examined liking for happy- and sad-sounding music as a function of exposure, which varied both in quantity (number of exposures) and in quality (focused or incidental listening). Liking ratings were higher for happy than for sad music after focused listening, but similar after incidental listening. In the incidental condition, liking ratings increased linearly as a function of exposure. In the focused condition, liking ratings were an inverted U-shaped function of exposure, with initial increases in liking (after 2 exposures) followed by decreases (after 8 or 32 exposures). The results documented that: (1) sad music is liked as much as happy music in some instances; (2) frequency of exposure causes both familiarity (positive) and over-familiarity (negative) effects; and (3) effects of exposure on liking differ for focused and incidental listening. 相似文献
AbstractThis meta-analytic review evaluates 35 parenting programs to analyze their effectiveness at reducing young children’s externalizing behavior (EB). It looks at whether behavioral or cognitive orientation, informant or duration of these programs moderate their effect on such young children. It confirms that parenting interventions are effective at decreasing young children’s EB but no moderation effect was found for specific orientation or duration, only for the informant. This illustrates the current difficulty in comparing programs on the basis of their theoretical background, which prevents the understanding of which are the most efficient parenting variables and change processes to manipulate. 相似文献
Habituation – the most basic form of learning – is used to evaluate central nervous system (CNS) maturation and to detect abnormalities in fetal brain development. In the current study, habituation, stimulus specificity and dishabituation of auditory evoked responses were measured in fetuses and newborns using fetal magnetoencephalography (fMEG). An auditory habituation paradigm consisting of 100 trains of five 500 Hz tones, one 750 Hz tone (dishabituator) and two more 500 Hz tones, respectively, were presented to 41 fetuses (gestational age 30–39 weeks) and 22 newborns or babies (age 6–89 days). A response decrement between the first and fifth tones (habituation), an increment between the fifth tone and the dishabituator (stimulus specificity) and an increment between the fifth (last tone before the dishabituator) and seventh tones (first tone after the dishabituator) (dishabituation) were expected. Fetuses showed weak responses to the first tone. However, a significant response decrement between the second and fifth tones (habituation) and a significant increment between the fifth tone and the dishabituator (stimulus specificity) were found. No significant difference was found for dishabituation nor was a developmental trend found at the group level. From the neonatal data, significant values for stimulus specificity were found. Sensory fatigue or adaptation was ruled out as a reason for the response decrement due to the strong reactions to the dishabituator. Taken together, the current study used fMEG to directly show fetal habituation and provides evidence of fetal learning in the last trimester of pregnancy. 相似文献