Psychological factors and depressive symptoms in ischemic heart disease.

The aim of this study was to determine whether learned helplessness, cognitive distortions, self-efficacy, and dispositional optimism assessed at Time 1 (T1; questionnaires mailed at 1 month postdischarge) would predict depressive symptoms at Time 2 (T2; questionnaires mailed at 1-year follow-up) in a sample of 86 patients hospitalized with ischemic heart disease. Multiple regression results indicated that optimism and cognitive distortions at T1 were significantly associated with T1 depressive symptoms after controlling for confounding variables. When the T1 psychological factors were analyzed with T2 depressive symptoms, only optimism continued to predict depressive symptoms after controlling for confounds and T1 depressive symptoms. The global expectancies that optimism assessed appeared to be more stable over time than the statelike beliefs of cognitive distortions and may have accounted for why optimism predicted T2 depressive symptoms.     

Psychometric analysis of the Stunkard-Messick Eating Questionnaire (SMEQ) and Comparison with the dutch Eating Behavior Questionnaire (DEBQ)

The factor structure of the Stunkard-Messick Eating Questionnaire (SMEQ) differs from that of the Dutch Eating Behavior Questionnaire (DEBQ). Using students and members of a weight watchers club, we factor-analyzed responses to the SMEQ and produced a solution which was different from that obtained by Stunkard and Messick, but which had some similarities to the factor structure of the DEBQ. “External” taste items and “internal” hunger items loaded on the same factor, a finding inconsistent with externality theory but consistent with the common sense notion of appetite strength. Although our finding suggests factor instability of the SMEQ, the stability of the DEBQ appears to be the consequence of a restricted range of DEBQ items compared with SMEQ items. Financial support for this research was given by Lilly Industries.     

Induction and activity-dependent reversal of persistent LTP and LTD in lateral perforant path synapses in vivo

The reversibility of long-term potentiation (LTP) and heterosynaptic long-term depression (LTD) lasting weeks was examined in the lateral perforant path of freely moving adult Sprague-Dawley rats. LTP lasting weeks was rapidly reversed within minutes by high-frequency heterosynaptic stimulation of the medial perforant path, in an N-methyl-D-aspartate receptor-dependent manner. LTP reversal also occurred, albeit more slowly and to a lesser extent, when animals were given 1-3 weeks of overnight exposure to an enriched environment (EE). LTD likewise was reversed upon repeated EE exposure. A covert similarity between the degrees of LTP and LTD reversal was revealed when the small potentiation effect of EE treatment by itself on lateral path responses was taken into account. Despite its ability to reverse previously acquired synaptic plasticity, two weeks of EE treatment had no effect on animals' retention of the platform location in a spatial watermaze task, although it did facilitate new learning. These data are in agreement with the hypothesis that hippocampal synapses retain the capacity for rapid synaptic change even when otherwise relatively stable plasticity has previously been induced. Slow reversal of such plasticity did not correlate with a loss of memory retention, possibly because either slow changes permit reorganization of representations such that both old and new information can be accommodated, or else the new information is synaptically represented in orthogonal fashion to the old information.     

Contingency management of exercise by chronic schizophrenics

Research on the control and maintenance of exercise by chronic schizophrenics has been relatively neglected, despite widespread knowledge of the adverse consequences of sedentary living. The present study evaluated the effects of simple contingency-management procedures designed to encourage exercising by two psychotic residents living in a sheltered group home. For both subjects, the ABAB experimental analysis demonstrated the effectiveness of the intervention. Improved levels of exercise were maintained at follow-up and the contingency-management system was implemented as a regular part of the group home's rehabilitation program for all residents.     

Fear of hypoglycemia: relationship to physical and psychological symptoms in patients with insulin-dependent diabetes mellitus.

Among diabetic patients, experience with hypoglycemia ranges from the unpleasant to the life threatening. The aversiveness of these episodes often results in fear. To examine the impact of hypoglycemia on fear, 69 patients with insulin-dependent diabetes mellitus completed the Behavior and Worry subscales of the Hypoglycemia Fear Survey along with measures of psychological symptoms, perceived stress, risk of future hypoglycemic episodes, and glycosylated hemoglobin. Behavior and Worry scores were positively related to psychological symptoms, perceived stress, and previous experiences with hypoglycemia. Fear was unrelated to glycosylated hemoglobin but was significantly higher for patients who had greater variability and lower mean daily blood glucose.     

Shifting goal posts: First and second order access

Snodgrass et al.’s (2009) commentary makes explicit one of the major problems in consciousness research; that there seem to be just as many definitions of basic terms are there are people in the field. Although Snodgrass et al.’s position appears at odds with the views expressed in Irvine (2009), many of their arguments are actually consistent with the proposed views, or else fail to engage with them as a consequence of the shifting goal posts of what basic terms mean.