Conscientiousness predicts disease progression (CD4 number and viral load) in people living with HIV.

OBJECTIVE: Psychosocial factors (e.g., depression, avoidant coping, life stress) have been related to disease progression in HIV. This study examined the relationship between the Big Five Conscientiousness factor and HIV disease progression (CD4 cell and viral load) over 1 year in 119 seropositive participants. The study also examined whether Conscientiousness effects were mediated by adherence, perceived stress, depression, or coping measures. DESIGN: In a 1-year longitudinal design, participants completed the NEO Five-Factor Inventory Conscientiousness scale (P. T. Costa & R. R. McCrae, 1992). Participants also completed psychosocial assessments and underwent blood draws at initial assessments and 1-year follow-up. MAIN OUTCOME MEASURES: Multiple hierarchical regression models were used to predict change in CD4 cell numbers and viral load log 10, controlling for demographic variables, initial disease status, and antiretroviral medications. RESULTS: Conscientiousness predicted significant increases in CD4 number and significant decreases in viral load at 1 year. Conscientiousness was related positively to medication adherence and active coping and negatively to depression and perceived stress. Only perceived stress emerged as a possible mediator. CONCLUSION: The significant relationship between Conscientiousness and medication adherence, distress, and coping suggests that an assessment of Conscientiousness in patients with HIV may help specify or target behavioral interventions to promote optimal disease management.     

Volunteer Work,Religious Commitment,and Resting Pulse Rates

Research indicates that greater involvement in volunteer activities is associated with better health. We aim to contribute to this literature in two ways. First, rather than rely on self-reports of health, measured resting pulse rates serve as the dependent variable. Second, an effort is made to see if religious commitment moderates the relationship between volunteering and resting pulse rates. Data that come from a recent nationwide survey (N = 2265) suggest that volunteer work is associated with lower resting pulse rates. The results also reveal that the relationship between engaging in volunteer work and resting pulse rates improves among study participants who are more deeply committed to religion.     

Verhaltensmedizin bei HIV-Infektion

Zusammenfassung Unsere Studien über asymptomatische, mit dem "human immunodeficiency virus" (HIV) infizierte homosexuelle Männer zeigen, dass kognitiv-behaviorales Stressmanagement (CBSM) ein geeignetes Mittel ist, die durch die Mitteilung eines positiven HIV-Befundes verursachte psychische Belastung zu reduzieren und zugleich einige immunologische Parameter zu modifizieren. Aus neueren Studien über HIV-infizierte Männer mit Prä-Aids-Symptomatik geht hervor, dass CBSM beitragen kann: a) Dysphorie, Angst und Stresssymptome zu lindern; b) Kortisol und Noradrenalin zu reduzieren und die Testosteronwerte zu erhöhen; c) die Zahl der Antikörper gegen einige Herpes-Viren zu reduzieren und zugleich die Zahl der T-zytotoxischen/Suppressorzellen (CD8) und der naiven T-Helfer- (CD4-) Lymphozyten aufrechtzuerhalten. Vorläufige Daten unserer neuesten Studien weisen darauf hin, dass mit CBSM die Viruslast bei Männern, die hoch aktive antiretrovirale Therapie erhalten, reduziert werden kann.Aus dem Englischen übersetzt von Dipl.-Psych. Erika Nemény, Berlin und Prof. Dr. Ulrike Ehlert, Zürich     

The Protective Role of the Family and Social Support Network in a Sample of HIV-Positive African American Women: Results of a Pilot Study

This study examined the role of family functioning and social support in protecting HIV-positive African American women from the adverse psychological consequences associated with deterioration in their CD4 cell count. Participants were 38 African American HIV-positive women who had recently given birth. Results demonstrated that changes in CD4 cell counts were inversely predictive of psychological distress and were moderated by family functioning and social support satisfaction. Women with good family functioning were less affected by changes in their CD4 cell counts, and women with poor family functioning were more emotionally responsive to changes in CD4 cell count. Unexpectedly, women from families where conflicts tended to be clearly laid out and discussed were also more responsive to both changes in CD4 cell counts. Interventions are recommended that increase a client's social support satisfaction, foster an adaptive level of connectedness to family, and enhance the family's range of conflict resolution styles.     

Concerns about breast cancer and relations to psychosocial well-being in a multiethnic sample of early-stage patients.

Much work on psychosocial sequelae of breast cancer has been guided by the assumption that body image and partner reaction issues are focal. In a tri-ethnic sample of 223 women treated for early-stage breast cancer within the prior year, the authors assessed a wider range of concerns and relations to well-being. Strongest concerns were recurrence, pain, death, harm from adjuvant treatment, and bills. Body-image concerns were moderate; concern about rejection was minimal. Younger women had stronger sexual and partner-related concerns than older women. Hispanic women had many stronger concerns and more disruption than other women. Life and pain concerns and sexuality concerns contributed uniquely to predicting emotional and psychosexual disruption; life and pain concerns and rejection concerns contributed to predicting social disruption. In sum, adaptation to breast cancer is a process bearing on several aspects of the patient's life space.     

Social Support Mediates Loneliness and Human Herpesvirus Type 6 (HHV-6) Antibody Titers

The current study investigated the impact of a severe environmental stressor and the role that declining social integration played in mediating its effect on loneliness and immune status. Increased loneliness and decreased social support in the months following the stressor (storm) were significantly associated with increased HHV-6 antibody liters, reflecting poorer control over the virus. Poorer social integration mediated the relationship between loneliness and HHV-6, even after controlling for nonspecific polyclonal B-cell activation, disease status (CD3+CD4+ cell counts), living arrangements, acute social losses (bereavement), and potential disruptions in social-support resources. These findings suggest that specific elements of social support may explain the oft-noted negative effects of loneliness on the immune system, and generalized to a medically vulnerable population.     

God-mediated control beliefs and the Epstein-Barr virus: Is more God-mediated control always better?

Research on the locus of control construct conveys the impression that more control is always better. However, some studies suggest that very high levels of control are associated with negative outcomes. The purpose of this study was to see if this is true of religiously oriented feelings of control (i.e., God-mediated control). The outcome was antibody titers to the Epstein-Barr virus (EBV). The findings suggest that very high God-mediated control is associated with higher EBV values. However, this finding was only observed among young adults (age 18–40), but not among middle-aged (age 41–64), or older adults (aged 65 and older).     

Exploring religious and/or spiritual identities: part 1 – assessing relationships with health

ABSTRACT

There is considerable debate about the distinction between being religious and being spiritual. It is time to move beyond this issue to an examination of the health-related implications of being religious and/or spiritual. Three health outcomes are used in this study: self-rated health, depressive symptoms, and alcohol use. The data are from a large nationwide random probability survey of adults of all ages who reside in the United States (N?=?2,876–2,883). Four self-identified categories of religiousness/spirituality are examined: religious and spiritual, spiritual only, not religious/not spiritual, and religious only. Tests are performed to see if membership in each category offsets the noxious effects of lifetime trauma on the health-related outcomes. A clear pattern emerges from the data. Lifetime trauma is associated with less favourable health ratings, more symptoms of depression, and greater alcohol consumption. However, these relationships are substantially stronger among people who say they are religious only.