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61.
Paradoxically, the practical necessity of love seems to combine the personal character of psychological necessity with the inescapable and authoritative quality of moral necessity. Traditionally, philosophers have avoided this paradox by treating love as an amalgam of impersonal evaluative judgments and affective responses. On my account, love participates in a different form of practical necessity, one characterized by a non‐moral yet normative type of expectation. This expectation is best understood as a kind of second‐personal address that does not support derivative third‐personal demands. It is revealed when we react with hurt feelings instead of resentment upon its disappointment.  相似文献   
62.
This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on the following key issues:
  1. § 1.
    Providing information about research integrity
     
  2. § 2.
    Providing education, training and mentoring
     
  3. § 3.
    Strengthening a research integrity culture
     
  4. § 4.
    Facilitating open dialogue
     
  5. § 5.
    Wise incentive management
     
  6. § 6.
    Implementing quality assurance procedures
     
  7. § 7.
    Improving the work environment and work satisfaction
     
  8. § 8.
    Increasing transparency of misconduct cases
     
  9. § 9.
    Opening up research
     
  10. § 10.
    Implementing safe and effective whistle-blowing channels
     
  11. § 11.
    Protecting the alleged perpetrators
     
  12. § 12.
    Establishing a research integrity committee and appointing an ombudsperson
     
  13. § 13.
    Making explicit the applicable standards for research integrity
     
  相似文献   
63.
Stories about community work in New Zealand and Scotland are presented to describe and reflect on issues central to feminist community psychology. Organizing a lesbian festival, Ingrid Huygens describes feminist processes used to equalize resources across Maori (indigenous) and Pakeha (white) groups. Heather Hamerton presents her experiences as a researcher using collective memory work to reflect on adolescent experiences related to gender, ethnicity, and class. Sharon Cahill chronicles dilemmas and insights from focus groups about anger with women living in public housing in Scotland. Each story chronicles experiences related to oppression and privilege, and describes the author's emotions and reflections. Individually and collectively, the stories illustrate the potential offered by narrative methods and participatory processes for challenging inequalities and encouraging social justice.  相似文献   
64.
In this study, we examine the suitability of a relatively new imaging technique, arterial spin labeled perfusion imaging, for the study of continuous, gradual changes in neural activity. Unlike BOLD imaging, the perfusion signal is stable over long time-scales, allowing for accurate assessment of continuous performance. In addition, perfusion fMRI provides an absolute measure of blood flow so signal changes can be interpreted without reference to a baseline. The task we used was the serial response time task, a sequence learning task. Our results show reliable correlations between performance improvements and decreases in blood flow in premotor cortex and the inferior parietal lobe, supporting the model that learning procedures that increase efficiency of processing will be reflected in lower metabolic needs in tissues that support such processes. More generally, our results show that perfusion fMRI may be applied to the study of mental operations that produce gradual changes in neural activity.  相似文献   
65.
The regulation and function of the calcium-dependent phosphatase calcineurin (CaN, protein phosphatase 2B) in learning and memory remain unclear, although recent work indicates that CaN may play a differential role in training and reversal training. To gain more insight into the involvement of CaN in these two types of learning, hippocampal CaN activity, protein levels, and expression patterns were studied in mice subjected to a reference memory version of the Y-maze task. We show that (1) training but not habituation induces a decrease in cytosolic CaN activity, (2) the recovery of cytosolic CaN activity is reversal training specific and does not reflect normal restoration of basal levels unrelated to subsequent learning, (3) cytosolic protein levels for the catalytic subunit of CaN (CaNA) are decreased at the early phase of training, but not at the early phase of reversal training, (4) CaNA immunoreactivity in the dorsal hippocampus is enhanced in the CA1 and CA3 area (but not in the dentate gyrus [DG] or subiculum [SUB]) only during reversal training. These findings indicate that memory formation is accompanied by reduced CaN activity, whereas adapting to changes in a familiar environment is accompanied by restored CaN activity. Moreover, reversal training selectively affects hippocampal CA3 and CA1 regions, suggesting a specific function of these hippocampal subregions in reversal learning.  相似文献   
66.
Impairment of hippocampal function precedes frontal and parietal cortex impairment in human Alzheimer's disease (AD). Neurotrophins are critical for behavioral performance and neuronal survival in AD. We used complex and radial mazes to assess spatial orientation and learning in wild-type and B6-Tg(ThylAPP)23Sdz (APP23) animals, a transgenic mouse model of AD. We also assessed brain content of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3). Performance was alike in wild-type and APP23 animals in the radial maze. In contrast, performance in the complex maze was better in wild-type than APP23 animals. Contrary to the wild-type, hippocampal BDNF levels decreased on training in APP23 animals. Hippocampal and frontal cortex NGF levels in APP23 animals correlated with the time to solve the complex maze, but correlated inversely with escape time in wild-type animals. NT-3 levels were alike in wild-type and APP23 animals and were unchanged even after training. Both types of mazes depend on hippocampal integrity to some extent. However, according to the cognitive mapping theory of spatial learning, the complex maze because of the increased complexity of the environment most likely depends more strongly on preserved hippocampal function than the radial maze in the working memory configuration applied here. Greater impairment in complex maze performance than in radial maze performance thus resembles the predominant affliction of the loss of hippocampal function in human AD. NGF and BDNF levels on maze learning are different in wild-type and transgenic animals, indicating that biological markers of AD may be altered on challenge even though equilibrium levels are alike.  相似文献   
67.
Boundary extension is the tendency to remember more of a scene than was actually shown. The dominant interpretation of this memory illusion is that it originates from schemata that people construct when viewing a scene. Evidence of boundary extension has been obtained primarily with adult participants who remember neutral pictures. The current study addressed the developmental stability of this phenomenon. Therefore, we investigated whether children aged 10-12 years display boundary extension for neutral pictures. Moreover, we examined emotional scene memory. Eighty-seven children drew pictures from memory after they had seen either neutral or emotional pictures. Both their neutral and emotional drawings revealed boundary extension. Apparently, the schema construction that underlies boundary extension is a robust and ubiquitous process.  相似文献   
68.
Most models of visuospatial attention include the notion that attention is dedicated to a single location in space. However, several researchers have found evidence that under appropriate circumstances, attention may be allocated to noncontiguous locations (e.g., Awh & Pashler, 2000; Bichot, Cave, & Pashler, 1999; Kramer & Hahn, 1995). In the present experiments, the spatial distribution of attention was assessed by a novel method, perceptual latency priming: the latency benefit of an attended visual stimulus, as compared with a nonattended stimulus. Experiment 1 assessed whether observers are able to attend to two nonadjacent regions or a region of variable size. Experiment 2 tested whether, when two distant locations are attended to, the region between them is necessarily also in the focus of attention. Two further experiments controlled for objections against the method used and replicated the main results of the first two experiments. The experiments showed a robust attentional priming effect at two noncontiguous locations of the visual field, simultaneous with little or no priming of the intervening location.  相似文献   
69.
In the present study, attachment-related differences in long-term memory for a highly emotional life event, child sexual abuse (CSA), were investigated. Participants were 102 documented CSA victims whose cases were referred for prosecution approximately 14 years earlier. Consistent with the proposal that avoidant individuals defensively regulate the processing of potentially distressing information (Bowlby, 1980), attachment avoidance was negatively associated with memory for particularly severe CSA incidents. This finding was not mediated by the extent to which participants reported talking about the abuse after it occurred, although post abuse discussion did enhance long-term memory. In addition, accuracy was positively associated with maternal support following the abuse and extent of CSA-related legal involvement. Attachment anxiety was unrelated to memory accuracy, regardless of abuse severity. Implications of the findings for theories of avoidant defensive strategies and emotional memory are discussed.  相似文献   
70.
Does a behavioral and anatomical division exist between spatial and object working memory? In this article, we explore this question by testing human participants in simple visual working memory tasks. We compared a condition in which there was no location change with conditions in which absolute location change and absolute plus relative location change were manipulated. The results showed that object memory was influenced by memory for relative but not for absolute location information. Furthermore, we demonstrated that relative space can be specified by a salient surrounding box or by distractor objects with no touching surfaces. Verbal memory was not influenced by any type of spatial information. Taken together, these results indicate that memory for "where" influences memory for "what." We propose that there is an asymmetry in memory according to which object memory always contains location information.  相似文献   
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