A case of hysteria, with a note on biology

Psychoanalysis recently has shown interest in the data of neurobiology. This interest has been fostered by the realization that a model of Cartesian mind-body dualism is inadequate to current observation and knowledge. Despite the theoretical appeal of integrating knowledge from the two fields, there have been few attempts at correlation in specific clinical situations. This paper presents a case of hysteria in which the physical manifestations of hyperprolactinemia, galactorrhea, amenorrhea, and infertility are considered in relation to both the brain regulation of prolactin and to unconscious fantasy, motivation, and conflict. Some of the intriguing possibilities and limitations of research at the frontier of psychoanalysis and neurophysiology are discussed.     

Lack of positive experiences and positive expectancies mediate the relationship between BAS responsiveness and depression

The anhedonic symptoms of depression have been linked to a lack of incentive responsiveness, which is a function of the Behavioral Activation System (BAS). Using structural equation modeling within the context of a cross-sectional design, we found that a lack of positive experiences and positive expectancies mediated the BAS-depression link among an undergraduate sample (N = 171). We tested the specificity of this model across four alternative models substituting negative experiences, negative expectancies, threat sensitivity, and symptoms of anxiety for their theoretical counterparts in the original model. In each case, the alternative model did not fit the data as well as our original model. This pattern of results is consistent with the position that a lack of positive experiences and positive expectancies uniquely mediate the relationship between the BAS and anhedonic symptoms of depression.