The medical research council’s approach to allegations of scientific misconduct

The UK’s Medical Research Council (MRC) introduced a specific policy and procedure for inquiring into allegations of scientific misconduct in December 1997; previously cases had been considered under normal disciplinary procedures. The policy formally covers staff employed in MRC units, but those in receipt of MRC grants in universities and elsewhere are expected to operate under similar policies. The MRC’s approach is stepwise: preliminary action; assessment to establish prima facie evidence of misconduct; formal investigation; sanctions; and appeal. Strict time limits apply at all stages. The procedure will be evaluated after two years. The indications so far are that the procedure is robust, and its clarity and transparency have been an asset to all parties. The MRC is also convinced that it is equally important to achieve a working culture that fosters integrity. Thus education and training in good research practices are fundamental to the prevention of research misconduct. This paper was presented at a symposium, Scientific Misconduct: An International Perspective, organized by The Medical University of Warsaw, 16 November, 1998.     

Induced mood change and dysfunctional attitudes in remitted bipolar I affective disorder

This study investigated the possibility that, in remitted bipolar I affective disorder, dysfunctional attitudes are mood-state dependent. Participants were 120 individuals with remitted bipolar I disorder, remitted unipolar depression, or no history of affective disorder. The Dysfunctional Attitudes Scale (DAS; Weissman, 1979) was completed before and after positive or negative mood challenge. Following mood increase, the bipolar group changed significantly less in DAS total score than did the other 2 groups, and in goal-striving and achievement attitudes relative to the unipolar group. These findings did not provide clear support for the mood-state dependency theory in bipolar disorder, arguing instead for the presence in bipolar I disorder of dysfunctional cognitions that show characteristic resilience in the face of minor positive mood increase.     

Meditations on Aggression,Loss, Discovery,and Influence in Psychoanalysis

Psychoanalysis requires acts of creative destruction. At the same time that analysts create new ways of being for themselves and each other, old ways are consequently destroyed. Just as parents envision futures for their children, analysts envision futures for their patients, reflecting a desire or effort to change them. Awareness of the destruction inherent in facilitating growth can enrich an analyst's work, but anxiety about being destructive, and being destroyed, can stifle it. This paper presents an analyst's reflections on creative and destructive aspects of psychoanalysis. Autobiographical and clinical data are presented to illuminate this theme.     

The Sortal Dependence of Demonstrative Reference

Abstract: ‘Sortalism about demonstrative reference’ is the view that the capacity to refer to things demonstratively rests on the capacity to classify them according to their kinds. This paper argues for one form of sortalism. Section 1 distinguishes two sortalist views. Section 2 argues that one of them is false. Section 3 argues that the other is true. Section 4 uses the argument from Section 3 to develop a new response to the objection to sortalism from examples where we seem to succeed in referring even though we get sortal classification wrong, or do not attempt to classify at all.     

System-Level Change in Cultural and Linguistic Competence (CLC): How Changes in CLC are Related to Service Experience Outcomes in Systems of Care

As US demographic trends shift toward more diversity, it becomes increasingly necessary to address differential needs of diverse groups of youth in mental health service systems. Cultural and linguistic competence (CLC) is essential to providing the most appropriate mental health services to youth and their families. The successful implementation of CLC often begins at the system level. Though various factors may affect change and system-level factors set the tone for broad acceptance of CLC within systems, there is limited empirical evidence linking culturally competent practices to outcomes. The purpose of the present study was to examine system-level CLC changes over time within systems of care and their associations with service experiences among youth and their families. Participants were 4,512 youth and their families enrolled in the national evaluation of the Children’s Mental Health Initiative (CMHI). Results suggest that implementation of CLC at the system level improves over time in funded systems of care. Further, variation exists in specific system-level components of CLC. In addition, the changes in CLC at the system level are related to family/caregiver participation in treatment. Implications for supporting positive changes in CLC among systems of care communities, and specific strategies for community psychologists, are discussed.     

How does episodic memory develop in adolescence?

Key areas of the episodic memory (EM) network demonstrate changing structure and volume during adolescence. EM is multifaceted and yet studies of EM thus far have largely examined single components, used different methods and have unsurprisingly yielded inconsistent results. The Treasure Hunt task is a single paradigm that allows parallel investigation of memory content, associative structure, and the impact of different retrieval support. Combining the cognitive and neurobiological accounts, we hypothesized that some elements of EM performance may decline in late adolescence owing to considerable restructuring of the hippocampus at this time. Using the Treasure Hunt task, we examined EM performance in 80 participants aged 10–17 yr. Results demonstrated a cubic trajectory with youngest and oldest participants performing worst. This was emphasized in associative memory, which aligns well with existing literature indicating hippocampal restructuring in later adolescence. It is proposed that memory development may follow a nonlinear path as children approach adulthood, but that future work is required to confirm and extend the trends demonstrated in this study.

Episodic memory (EM) describes the ability to encode, store, and retrieve representations of previously experienced episodes and their temporal-spatial context (Tulving 1972). EM development continues well into the third decade of life (Ruggiero et al. 2016); however, its developmental trajectory after the preschool years remains controversial, with some studies suggesting linear improvements (Ofen et al. 2007) and others no improvement (Picard et al. 2012) or a nonlinear pattern (Tulving 1985; Keresztes et al. 2017). While there has been some debate as to the “defining features” of EM (Cheke and Clayton 2013, 2015) most theorists agree that it is not a unitary ability, instead reflecting the combination of a number of contributing features. Given that many of these studies used different methods for testing EM, and that different tests may emphasize different features (Cheke and Clayton 2013, 2015), it is likely that empirical differences reflect the fact that different features of memory may develop differently during later childhood and adolescence (Picard et al. 2012).The importance of understanding the developmental trajectory of EM in adolescence is highlighted in the close association between EM and other cognitive processes. EM is thought to support decision-making, particularly in the incorporation of memories into task- and goal-relevant responses (Murty et al. 2016); thus, immaturity of EM may influence the high levels of risk taking observed in adolescence. Adolescence also represents a period of vulnerability to the development of mental illness (Kessler et al. 2007). Evidence that deficits in EM have been linked to a number of mental health disorders such as depression (Goodwin 1997) and anxiety (Airaksinen et al. 2005) raises the possibility that individual differences in memory development during this period may influence this vulnerability. Finally, adolescence is a demanding time academically: During these school years, large quantities of knowledge must be acquired to be successful in exams, which have long-term impacts on individuals’ academic and professional future. It is therefore important to understand factors that may contribute to individual differences and challenges in learning and memory during this period.Memory development in adolescence has attracted considerable research attention in recent years, with the majority of work conducted on developmental trajectories of brain areas within the memory network. EM relies on a distributed network of brain areas, including the medial temporal and superior parietal lobes and the prefrontal cortex (PFC) (Simons and Spiers 2003). Each area within the network, as well as the network itself, shows protracted maturation across adolescence.