慢性应激对大鼠海马Akt/FKHRL1信号通路活性的影响

探讨慢性应激对大鼠海马Akt/FKHRL1信号通路活性的影响,及其应激源特异性。将24只雄性SD大鼠随机分为心理应激组、束缚应激组和正常对照组（n=8）。用Western-blotting方法测定28天应激后海马Akt、FKHRL1蛋白含量及其磷酸化水平。结果表明,应激后三组大鼠海马磷酸化Akt、FKHRL1含量差异有统计学意义（p < 0.01;p < 0.001）,束缚应激组低于正常对照组（p < 0.01）。提示慢性应激能导致海马磷酸化Akt、FKHRL1表达水平降低,但其影响程度与应激源特异性有关     

No Benefit of Eye-Closure Rehearsal in a Unimodal Recognition Memory Test for Word Items

Recent studies have suggested that closing the eyes helps memory retrieval in recall tests for audiovisual clips that contain multimodal information. In two experiments, we examined whether eye-closure improves recognition memory performance for word lists presented unimodally (i.e., visually or aurally). In the encoding phase, participants saw or heard a list of unrelated, meaningful word items. After a fixed retention interval of 1 week (Experiment 1, n = 110) and 5 min (Experiment 2, n = 44), the participants were asked to mentally rehearse the items with their eyes open or closed, and then they performed a recognition test. The results revealed no effect of eye-closure rehearsal on recognition performance. We discuss the possible reasons why no eye-closure benefit was found in recognition memory tests for unrelated word items.     

Motion impressions enhanced by converging motion lines

We investigated how motion lines drawn in the background of a running human silhouette affect motion impressions of a runner in a static image. Observers evaluated the strength and direction of motion impression. The results show that parallel lines do not enhance frontoparallel motion impressions, while converging lines do so in an in-depth direction. This is a counter-example to the hypothesis that motion lines in the background represent motion streaks of the background when one visually tracks a moving object.     

A developmental shift from similar to language-specific strategies in verb acquisition: A comparison of English,Spanish, and Japanese

The world’s languages draw on a common set of event components for their verb systems. Yet, these components are differentially distributed across languages. At what age do children begin to use language-specific patterns to narrow possible verb meanings? English-, Japanese-, and Spanish-speaking adults, toddlers, and preschoolers were shown videos of an animated star performing a novel manner along a novel path paired with a language-appropriate nonsense verb. They were then asked to extend that verb to either the same manner or the same path as in training. Across languages, toddlers (2- and 2.5-year-olds) revealed a significant preference for interpreting the verb as a path verb. In preschool (3- and 5-year-olds) and adulthood, the participants displayed language-specific patterns of verb construal. These findings illuminate the way in which verb construal comes to reflect the properties of the input language.     

Random Walker Test: A computerized alternative to the Road-Map Test

The Road-Map Test (RMT) is a popular neurological assessment of left-right orientation, using a simplified road map. Inspired by the RMT, we developed a new computerized navigation test, the Random Walker Test (RWT), for further quantitative assessment of left-right orientation ability. RWT provides verbal or nonverbal instructions for the direction (left, right, or front) in which to proceed, and participants must judge the spatially correct direction. Perspectives rotate by 90° during navigation. Verbal judgments demand verbal-to-spatial mapping of left/right/front and, if necessary, egocentric perspective rotation. Using the RWT, we evaluated the left-right orientation of normal male participants. The RWT reliably recorded the response times and error rates for participant performance and also revealed egocentric perspective rotation as an unreliable mental process with large intra- and interpersonal variability. These results indicate that the RWT may be useful in investigating left-right orientation and/or egocentric perspective rotation in both normal participants and neuropathological patients.     

Sound symbolism facilitates early verb learning

Some words are sound-symbolic in that they involve a non-arbitrary relationship between sound and meaning. Here, we report that 25-month-old children are sensitive to cross-linguistically valid sound-symbolic matches in the domain of action and that this sound symbolism facilitates verb learning in young children. We constructed a set of novel sound-symbolic verbs whose sounds were judged to match certain actions better than others, as confirmed by adult Japanese- as well as English speakers, and by 2- and 3-year-old Japanese-speaking children. These sound-symbolic verbs, together with other novel non-sound-symbolic verbs, were used in a verb learning task with 3-year-old Japanese children. In line with the previous literature, 3-year-olds could not generalize the meaning of novel non-sound-symbolic verbs on the basis of the sameness of action. However, 3-year-olds could correctly generalize the meaning of novel sound-symbolic verbs. These results suggest that iconic scaffolding by means of sound symbolism plays an important role in early verb learning.     

Background stripes affect apparent speed of rotation

A gray line that rotated about its own center against a stationary background of vertical stripes appeared to double in perceptual speed as it rotated through the vertical position and thus momentarily aligned with the background. Four factors may contribute to this speed-up: (i) landmarks, in which the tip of the moving vertical line moves horizontally across the maximum number of stationary stripes; (ii) orientation repulsion of the moving line by the vertical stripes, which may distort the line's perceived position and hence its perceived speed; (iii) the orientation of an induced brightness pattern along the line; and (iv) the motion of the induced brightness pattern, which moves physically most rapidly along the line when the line is near vertical. To test these possibilities, an annulus display provided landmarks but no intersections, and this almost abolished the effect. A rotating-slit display provided an oriented, moving pattern that mimicked the induced brightness but had no landmarks, and this increased the effect. We conclude that the motion, but not the orientation, of the intersections [option (iv)] was responsible for the illusion. The fact that this motion along the length of the line affected the perceived speed of the line orthogonal to its own length indicates a failure on the part of the visual system to fully decouple tangential from radial motion.     

GazeParser: an open-source and multiplatform library for low-cost eye tracking and analysis

Eye movement analysis is an effective method for research on visual perception and cognition. However, recordings of eye movements present practical difficulties related to the cost of the recording devices and the programming of device controls for use in experiments. GazeParser is an open-source library for low-cost eye tracking and data analysis; it consists of a video-based eyetracker and libraries for data recording and analysis. The libraries are written in Python and can be used in conjunction with PsychoPy and VisionEgg experimental control libraries. Three eye movement experiments are reported on performance tests of GazeParser. These showed that the means and standard deviations for errors in sampling intervals were less than 1 ms. Spatial accuracy ranged from 0.7° to 1.2°, depending on participant. In gap/overlap tasks and antisaccade tasks, the latency and amplitude of the saccades detected by GazeParser agreed with those detected by a commercial eyetracker. These results showed that the GazeParser demonstrates adequate performance for use in psychological experiments.     

All Giraffes Have Female‐Specific Properties: Influence of Grammatical Gender on Deductive Reasoning About Sex‐Specific Properties in German Speakers

Grammatical gender is independent of biological sex for the majority of animal names (e.g., any giraffe, be it male or female, is grammatically treated as feminine). However, there is apparent semantic motivation for grammatical gender classes, especially in mapping human terms to gender. This research investigated whether this motivation affects deductive inference in native German speakers. We compared German with Japanese speakers (a language without grammatical gender) when making inferences about sex‐specific biological properties. We found that German speakers tended to erroneously draw inferences when the sex in the premise and grammatical gender of the target animal agreed. An over‐generalization of the grammar–semantics mapping was found even when the sex of the target was explicitly indicated. However, these effects occurred only when gender‐marking articles accompanied the nouns. These results suggest that German speakers project sex‐specific biological properties onto gender‐marking articles but not onto conceptual representations of animals per se.     

Inconsistent locomotion inhibits vection

We measured the strength of illusory self-motion perception (vection) with and without locomotion on a treadmill. The results revealed that vection was inhibited by inconsistent locomotion, but facilitated by consistent locomotion.