On the alleged impossibility of coherence

If coherence is to have justificatory status, as some analytical philosophers think it has, it must be truth-conducive, if perhaps only under certain specific conditions. This paper is a critical discussion of some recent arguments that seek to show that under no reasonable conditions can coherence be truth-conducive. More specifically, it considers Bovens and Hartmann’s and Olsson’s “impossibility results,” which attempt to show that coherence cannot possibly be a truth-conducive property. We point to various ways in which the advocates of a coherence theory of justification may attempt to divert the threat of these results.     

Sexual Morality: Is Consent Enough?

The liberal view that valid consent is sufficient for a sex act to be morally legitimate is challenged by three major philosophies of sex: the Catholic view of sex as ordained for procreation and properly confined to marriage, the romantic view of sex as bound up with love, and the radical feminist analysis of sex in our society as part and parcel of the domination of women by men. I take a critical look at all three, focusing on Mary Geach's recent statement of the procreation view, Roger Scruton's theory of sexual desire as naturally evolving into intimacy and love, and several radical feminist discussions of sex in sexist society which argue that the notion of consent is unhelpful and, indeed, irrelevant. I argue that none of these lines of argument is convincing, and that consent remains the touchstone of morally permissible sex – although, dmittedly, it may not be very helpful in discussing ideals of human sexuality.     

Suicide Attempts in Major Depressed Patients with Personality Disorder

Suicide attempters who met criteria for borderline personality disorder (BPD) comorbid with major depressive disorder (MDD) were compared to both suicide attempters suffering from MDD alone and to attempters with comorbid MDD and other personality disorders (PD). Participants were 239 (158 patients with comorbid PD and 81 patients with MDD without comorbidity) inpatients consecutively admitted after a suicide attempt made in the last 24 hours. Suicide attempters with comorbid MDD and BPD had more frequent previous suicide attempts and were more likely to have a history of aggressive behaviors and alcohol and drug use disorders compared with patients suffering from MDD without Axis II comorbidity.     

Application of chaos theory to a model biological system: Evidence of self-organization in the intrinsic cardiac nervous system

The neural organization that determines the specific beat-to-beat pattern of cardiac behavior is expected to be demonstrated in the independent regulation of the RR intervals (chronotropy) and the corresponding QT subintervals (inotropy), as the former defines the rate of contraction and the latter has a linear negative correlation with the peak pressure inside the contracting ventricular muscles. The neurons of the isolated cardiac nervous system, many of which are located in the fat-pads of the heart, exhibit the same types of mechanical and chemical receptors and the same types of cholinergic and noradrenergic effectors as those found in the neural superstructure. In the surgically isolated and perfused rabbit heart we studied the responses of the QT and RR intervals evoked by block of coronary blood flow. We found that if we separated each RR cycle into QT and RR-QT components, then the dynamics of variation for each subinterval series often had the same fractional number of degrees of freedom (i.e., chaotic dimensions), a finding which suggests they are both regulated by the same underlying system. The ischemia/anoxia evoked transient dimensional increases and separations between the two subinterval series that, after the temporary divergence, reconverged to having the same lower value. The dimensional fluctuations occurred repeatedly and preceded or coincided with alterations in the magnitude and sign of the slope of QT vs RR-QT. We interpret the dimensional fluctuations of the two subinterval series as correlates of adaptation-dependent self-organization and reorganization in the underlying intrinsic cardiac nervous system during accumulating ischemia/anoxia. Such attempts at functional reorganization in this simple neurocardiac system may explain the transient dimensional changes in the RR intervals that precedes by 24 hrs the occurrences of fatal ventricular fibrillation in high-risk cardiac patients.     

Hintikka’s Independence-Friendly Logic Meets Nelson’s Realizability

Inspired by Hintikka’s ideas on constructivism, we are going to ‘effectivize’ the game-theoretic semantics (abbreviated GTS) for independence-friendly first-order logic (IF-FOL), but in a somewhat different way than he did in the monograph ‘The Principles of Mathematics Revisited’. First we show that Nelson’s realizability interpretation—which extends the famous Kleene’s realizability interpretation by adding ‘strong negation’—restricted to the implication-free first-order formulas can be viewed as an effective version of GTS for FOL. Then we propose a realizability interpretation for IF-FOL, inspired by the so-called ‘trump semantics’ which was discovered by Hodges, and show that this trump realizability interpretation can be viewed as an effective version of GTS for IF-FOL. Finally we prove that the trump realizability interpretation for IF-FOL appropriately generalises Nelson’s restricted realizability interpretation for the implication-free first-order formulas.     

Accuracy and performance of the state-based Φ and liveliness measures of information integration

A number of people have suggested that there is a link between information integration and consciousness, and a number of algorithms for calculating information integration have been put forward. The most recent of these is Balduzzi and Tononi’s state-based Φ algorithm, which has factorial dependencies that severely limit the number of neurons that can be analyzed. To address this issue an alternative state-based measure known as liveliness has been developed, which uses the causal relationships between neurons to identify the areas of maximum information integration. This paper outlines the state-based Φ and liveliness algorithms and sets out a number of test networks that were used to compare their accuracy and performance. The results show that liveliness is a reasonable approximation to state-based Φ for some network topologies, and it has a much more scalable performance than state-based Φ.     

Manual assisted cognitive treatment for deliberate self-harm in borderline personality disorder patients

This study examines the efficacy of a short-term individual therapy, Manual Assisted Cognitive Treatment (MACT), which was developed to treat parasuicidal (suicidal or self-harming) patients. In this trial, MACT was modified to focus on deliberate self-harm (DSH) in patients with borderline personality disorder (BPD). Thirty BPD patients who were engaged in DSH while in ongoing treatments, i.e., treatment-as-usual (TAU), were randomly assigned to receive MACT (N = 15) or not. DSH and level of suicide ideation were assessed at the baseline, at completion of the MACT intervention, and six months later. Results indicated that MACT was associated with significantly less frequent DSH upon completion of the intervention and with significantly decreased DSH frequency and severity at the six months follow-up. Moreover, MACT's contribution to reducing DSH frequency and severity was greater than the contribution by the amount of concurrent treatments. In contrast, MACT did not affect the level of suicide ideation and time-to-repeat of DSH. In conclusion, MACT seems to be a promising intervention for DSH in patients with BPD. More definitive studies are needed.     

The Anti-realist Argument for Underdetermination

Typically, anti-realists argue for the underdetermination of theory by the data (UD) on the basis of the claim that each theory has empirically equivalent rivals (EE). Leplin has recently sought to show that, whatever the truth-value of this latter claim, it cannot play any positive role in an argument for underdetermination. I argue that Leplin's attempt fails.